Hemolithin
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Hemolithin
Hemolithin (sometimes confused with the similar space polymer hemoglycin) is a proposed protein containing iron and lithium, of extraterrestrial origin, according to an unpublished preprint. The result has not been published in any peer-reviewed scientific journal. The protein was purportedly found inside two CV3 meteorites, Allende and Acfer-086, by a team of scientists led by Harvard University biochemist Julie McGeoch. The report of the discovery was met with some skepticism and suggestions that the researchers had extrapolated too far from incomplete data. Sources The detected hemolithin protein was reported to have been found inside two CV3 meteorites Allende and Acfer 086. Acfer-086, where the complete molecule was detected rather than fragments (Allende), was discovered in Agemour, Algeria in 1990. Structure According to the researchers' mass spectrometry, hemolithin is largely composed of glycine and hydroxyglycine amino acids. The researchers noted that the pr ...
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Allende Meteorite
The Allende meteorite is the largest carbonaceous chondrite ever found on Earth. The fireball was witnessed at 01:05 on February 8, 1969, falling over the Mexican state of Chihuahua. After it broke up in the atmosphere, an extensive search for pieces was conducted and over 2 tonnes (2.2 tons) were recovered. The availability of large quantities of samples of the scientifically important chondrite class has enabled numerous investigations by many scientists; it is often described as "the best-studied meteorite in history." The Allende meteorite has abundant, large calcium–aluminium-rich inclusions (CAI), which are among the oldest objects formed in the Solar System. Carbonaceous chondrites compose about 4 percent of all meteorites observed to fall from space. Prior to 1969, the carbonaceous chondrite class was known from a small number of uncommon meteorites such as Orgueil, which fell in France in 1864. Meteorites similar to Allende were known, but many were small and poorly ...
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Polymer
A polymer () is a chemical substance, substance or material that consists of very large molecules, or macromolecules, that are constituted by many repeat unit, repeating subunits derived from one or more species of monomers. Due to their broad spectrum of properties, both synthetic and natural polymers play essential and ubiquitous roles in everyday life. Polymers range from familiar synthetic plastics such as polystyrene to natural biopolymers such as DNA and proteins that are fundamental to biological structure and function. Polymers, both natural and synthetic, are created via polymerization of many small molecules, known as monomers. Their consequently large molecular mass, relative to small molecule compound (chemistry), compounds, produces unique physical property, physical properties including toughness, high rubber elasticity, elasticity, viscoelasticity, and a tendency to form Amorphous solid, amorphous and crystallization of polymers, semicrystalline structures rath ...
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Hemoglycin
Hemoglycin (previously termed hemolithin) is a space polymer that is the first polymer of amino acids found in meteorites. Structure Structural work has determined that its 1,494- dalton core unit (glycine18 / hydroxy-glycine4 / Fe2O4) contains iron, but not lithium, leading to the more general term hemoglycin for these molecules. The hemoglycin core contains a total of 22 glycine residues in an anti-parallel beta-sheet chain that is terminated at each end by an iron atom plus two oxygens. Four of these glycine residues are oxidized to hydroxy-glycine with hydroxy groups (−OH) on the alpha carbon. This structure was determined by mass spectrometry of meteoritic solvent extracts and has been confirmed in X-ray scattering by crystals of hemoglycin, and also by optical absorption. Crystals show a 480 nm characteristic absorption that can only exist when hydroxy-glycine residues have R chirality and are C-terminal bonded to iron. History Because hemoglycin has now be ...
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Iron
Iron is a chemical element; it has symbol Fe () and atomic number 26. It is a metal that belongs to the first transition series and group 8 of the periodic table. It is, by mass, the most common element on Earth, forming much of Earth's outer and inner core. It is the fourth most abundant element in the Earth's crust, being mainly deposited by meteorites in its metallic state. Extracting usable metal from iron ores requires kilns or furnaces capable of reaching , about 500 °C (900 °F) higher than that required to smelt copper. Humans started to master that process in Eurasia during the 2nd millennium BC and the use of iron tools and weapons began to displace copper alloys – in some regions, only around 1200 BC. That event is considered the transition from the Bronze Age to the Iron Age. In the modern world, iron alloys, such as steel, stainless steel, cast iron and special steels, are by far the most common industrial metals, due to their mechan ...
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Harvard University
Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyman John Harvard (clergyman), John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of Colonial history of the United States, colonial-era Massachusetts Bay Colony. While never formally affiliated with any Religious denomination, denomination, Harvard trained Congregationalism in the United States, Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston B ...
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Iron Oxide
An iron oxide is a chemical compound composed of iron and oxygen. Several iron oxides are recognized. Often they are non-stoichiometric. Ferric oxyhydroxides are a related class of compounds, perhaps the best known of which is rust. Iron oxides and oxyhydroxides are widespread in nature and play an important role in many geological and biological processes. They are used as iron ores, pigments, catalysts, and in thermite, and occur in hemoglobin. Iron oxides are inexpensive and durable pigments in paints, coatings and colored concretes. Colors commonly available are in the " earthy" end of the yellow/orange/red/brown/black range. When used as a food coloring, it has E number E172. Stoichiometries Iron oxides feature as ferrous ( Fe(II)) or ferric ( Fe(III)) or both. They adopt octahedral or tetrahedral coordination geometry. Only a few oxides are significant at the earth's surface, particularly wüstite, magnetite, and hematite. * Oxides of FeII ** FeO: ir ...
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Molecular Cloud
A molecular cloud—sometimes called a stellar nursery if star formation is occurring within—is a type of interstellar cloud of which the density and size permit absorption nebulae, the formation of molecules (most commonly molecular hydrogen, H2), and the formation of H II regions. This is in contrast to other areas of the interstellar medium that contain predominantly ionized gas. Molecular hydrogen is difficult to detect by infrared and radio observations, so the molecule most often used to determine the presence of H2 is carbon monoxide (CO). The ratio between CO luminosity and H2 mass is thought to be constant, although there are reasons to doubt this assumption in observations of some other galaxies. Within molecular clouds are regions with higher density, where much dust and many gas cores reside, called clumps. These clumps are the beginning of star formation if gravitational forces are sufficient to cause the dust and gas to collapse. Research and discovery The histo ...
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Protoplanetary Disk
A protoplanetary disk is a rotating circumstellar disc of dense gas and dust surrounding a young newly formed star, a T Tauri star, or Herbig Ae/Be star. The protoplanetary disk may not be considered an accretion disk; while the two are similar, an accretion disk is hotter and spins much faster; it is also found on black holes, not stars. This process should not be confused with the accretion process thought to build up the planets themselves. Externally illuminated photo-evaporating protoplanetary disks are called proplyds. Formation Protostars form from molecular clouds consisting primarily of molecular hydrogen. When a portion of a molecular cloud reaches a critical size, mass, or density, it begins to collapse under its own gravity. As this collapsing cloud, called a solar nebula, becomes denser, random gas motions originally present in the cloud average out in favor of the direction of the nebula's net angular momentum. Conservation of angular momentum causes the r ...
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Deuterium
Deuterium (hydrogen-2, symbol H or D, also known as heavy hydrogen) is one of two stable isotopes of hydrogen; the other is protium, or hydrogen-1, H. The deuterium nucleus (deuteron) contains one proton and one neutron, whereas the far more common H has no neutrons. The name ''deuterium'' comes from Greek '' deuteros'', meaning "second". American chemist Harold Urey discovered deuterium in 1931. Urey and others produced samples of heavy water in which the H had been highly concentrated. The discovery of deuterium won Urey a Nobel Prize in 1934. Nearly all deuterium found in nature was synthesized in the Big Bang 13.8 billion years ago, forming the primordial ratio of H to H (~26 deuterium nuclei per 10 hydrogen nuclei). Deuterium is subsequently produced by the slow stellar proton–proton chain, but rapidly destroyed by exothermic fusion reactions. The deuterium–deuterium reaction has the second-lowest energy threshold, and is the most astrophysically acce ...
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Space
Space is a three-dimensional continuum containing positions and directions. In classical physics, physical space is often conceived in three linear dimensions. Modern physicists usually consider it, with time, to be part of a boundless four-dimensional continuum known as '' spacetime''. The concept of space is considered to be of fundamental importance to an understanding of the physical universe. However, disagreement continues between philosophers over whether it is itself an entity, a relationship between entities, or part of a conceptual framework. In the 19th and 20th centuries mathematicians began to examine geometries that are non-Euclidean, in which space is conceived as '' curved'', rather than '' flat'', as in the Euclidean space. According to Albert Einstein's theory of general relativity, space around gravitational fields deviates from Euclidean space. Experimental tests of general relativity have confirmed that non-Euclidean geometries provide a bet ...
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Amino Acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although over 500 amino acids exist in nature, by far the most important are the 22 α-amino acids incorporated into proteins. Only these 22 appear in the genetic code of life. Amino acids can be classified according to the locations of the core structural functional groups ( alpha- , beta- , gamma- amino acids, etc.); other categories relate to polarity, ionization, and side-chain group type ( aliphatic, acyclic, aromatic, polar, etc.). In the form of proteins, amino-acid '' residues'' form the second-largest component (water being the largest) of human muscles and other tissues. Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. It is thought that they played a key role in enabling life on Earth and its emergence. Amino acids are formally named by the IUPAC- IUBMB Joint Commi ...
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Non-proteinogenic Amino Acids
In biochemistry, non-coded or non-proteinogenic amino acids are distinct from the 22 proteinogenic amino acids (21 in eukaryotesplus formylmethionine in eukaryotes with prokaryote organelles like mitochondria), which are naturally encoded in the genome of organisms for the assembly of proteins. However, over 140 non-proteinogenic amino acids occur naturally in proteins and thousands more may occur in nature or be synthesized in the laboratory. Chemically synthesized amino acids can be called unnatural amino acids. Unnatural amino acids can be synthetically prepared from their native analogs via modifications such as amine alkylation, side chain substitution, structural bond extension cyclization, and isosteric replacements within the amino acid backbone. Many non-proteinogenic amino acids are important: * intermediates in biosynthesis, * in post-translational formation of proteins, * in a physiological role (e.g. components of Peptidoglycan, bacterial cell walls, neurotransmitters ...
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