Granulation
Granulation is the process of forming grains or granules from a powdery or solid substance, producing a granular material. It is applied in several technological processes in the chemical and pharmaceutical industries. Typically, granulation involves agglomeration of fine particles into larger granules, typically of size range between 0.2 and 4.0 mm depending on their subsequent use. Less commonly, it involves shredding or grinding solid material into finer granules or pellets. From powder The granulation process combines one or more powder particles and forms a granule that will allow tableting to be within required limits. It is the process of collecting particles together by creating bonds between them. Bonds are formed by compression or by using a binding agent. Granulation is extensively used in the pharmaceutical industry, for manufacturing of tablets and pellets. This way predictable and repeatable process is possible and granules of consistent quality can be produce ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Tablet (pharmacy)
A tablet (also known as a pill) is a pharmaceutical oral dosage form (''oral solid dosage'', or OSD) or solid unit dosage form. Tablets may be defined as the solid unit dosage form of medication with suitable excipients. It comprises a mixture of active substances and excipients, usually in powder form, that are pressed or compacted into a solid dose. The main advantages of tablets are that they ensure a consistent dose of medicine that is easy to consume. Tablets are prepared either by moulding or by compression. The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive or aid in visual identification of an unknown tablet. A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the release rate ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Granular Material
A granular material is a conglomeration of discrete solid, macroscopic scale, macroscopic particles characterized by a loss of energy whenever the particles interact (the most common example would be friction when granulation, grains collide). The constituents that compose granular material are large enough such that they are not subject to thermal motion fluctuations. Thus, the lower size limit for grains in granular material is about 1 micrometre, μm. On the upper size limit, the physics of granular materials may be applied to ice floes where the individual grains are icebergs and to asteroid belts of the Solar System with individual grains being asteroids. Some examples of granular materials are snow, nut (fruit), nuts, coal, sand, rice, coffee, corn flakes, salt, and ball (bearing), bearing balls. Research into granular materials is thus directly applicable and goes back at least to Charles-Augustin de Coulomb, whose Friction, law of friction was originally stated for granul ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Granularity
Granularity (also called graininess) is the degree to which a material or system is composed of distinguishable pieces, "granules" or "grains" (metaphorically). It can either refer to the extent to which a larger entity is subdivided, or the extent to which groups of smaller indistinguishable entities have joined together to become larger distinguishable entities. Precision and ambiguity Coarse-grained materials or systems have fewer, larger discrete components than fine-grained materials or systems. * A coarse-grained description of a system regards large subcomponents. * A fine-grained description regards smaller components of which the larger ones are composed. The concepts granularity, coarseness, and fineness are relative; and are used when comparing systems or descriptions of systems. An example of increasingly fine granularity: a list of nations in the United Nations, a list of all states/provinces in those nations, a list of all cities in those states, etc. Physics A ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ethanol
Ethanol (also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound with the chemical formula . It is an Alcohol (chemistry), alcohol, with its formula also written as , or EtOH, where Et is the pseudoelement symbol for ethyl group, ethyl. Ethanol is a Volatility (chemistry), volatile, flammable, colorless liquid with a characteristic wine-like odor and pungent taste. As a psychoactive depressant, it is the active ingredient in alcoholic beverages, and the second most consumed drug globally behind caffeine. Ethanol is naturally produced by the fermentation process of sugars by yeasts or via petrochemical processes such as ethylene hydration. Historically it was used as a general anesthetic, and has modern medical applications as an antiseptic, disinfectant, solvent for some medications, and antidote for methanol poisoning and ethylene glycol poisoning. It is used as a chemical solvent and in the Chemical synthesis, synthesis of orga ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Plastic Recycling
Plastic recycling is the processing of plastic waste into other products. Recycling can reduce dependence on landfills, conserve resources and protect the environment from plastic pollution and greenhouse gas emissions. Recycling rates lag behind those of other recoverable materials, such as aluminium, glass and paper. From the start of plastic production through to 2015, the world produced around 6.3 billion tonnes of plastic waste, only 9% of which has been recycled and only ~1% has been recycled more than once. Of the remaining waste, 12% was incinerated and 79% was either sent to landfills or lost to the environment as pollution. Almost all plastic is non- biodegradable and without recycling, spreads across the environment where it causes plastic pollution. For example, as of 2015, approximately 8 million tonnes of waste plastic enters the oceans annually, damaging oceanic ecosystems and forming ocean garbage patches. Almost all recycling is mechanical and involves the m ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Screw Conveyor
A screw conveyor or auger conveyor is a mechanism that uses a rotating helical screw (simple machine), screw blade, called a "''flighting''", usually within a tube, to move liquid or granular materials. They are used in many bulk handling industries. Screw conveyors in modern industry are often used horizontally or at a slight incline as an efficient way to move semi-solid materials, including food waste, Woodchips, wood chips, aggregates, cereal, cereal grains, animal feed, boiler ash, meat, bone meal, municipal solid waste, and many others. The first type of screw conveyor was the Archimedes' screw, used since ancient times to pump irrigation water. They usually consist of a trough or tube containing either a spiral blade coiled around a shaft, driven at one end and held at the other, or a "''shaftless spiral''", driven at one end and free at the other. The rate of volume transfer is proportional to the rotation rate of the shaft. In industrial control applications, the de ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Die (manufacturing)
A die is a specialized machine tool used in manufacturing industries to cut and/or Forming (metalworking), form material to a desired shape or profile. ''Stamping (metalworking), Stamping dies'' are used with a machine press, press, as opposed to ''Draw plate, drawing dies'' (used in the manufacture of wire) and ''Die casting, casting dies'' (used in Molding (process), molding) which are not. Like molds, dies are generally customized to the item they are used to create. Products made with dies range from simple paper clips to complex pieces used in advanced technology. Continuous production, Continuous-feed laser cutting may displace the analogous die-based process in the automotive industry, among others. Die stamping Blanking and piercing are two Shearing (manufacturing), die cutting operations, and Bending (metalworking), bending is an example of a die forming operation. Die forming Forming operations work by deforming materials like sheet metal or plastic using force (Compre ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Extrusion
Extrusion is a process used to create objects of a fixed cross section (geometry), cross-sectional profile by pushing material through a Die (manufacturing), die of the desired cross-section. Its two main advantages over other manufacturing processes are its ability to create very complex cross-sections; and to work materials that are brittle, because the material encounters only compressive stress, compressive and shear stress, shear stresses. It also creates excellent surface finish and gives considerable freedom of form in the design process. Drawing (manufacturing), Drawing is a similar process, using the tensile strength of the material to pull it through the die. It limits the amount of change that can be performed in one step, so it is limited to simpler shapes, and multiple stages are usually needed. Drawing is the main way to produce wire. Metal Bar stock, bars and tube (fluid conveyance), tubes are also often drawn. Extrusion may be continuous (theoretically producin ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C). However, the agency also enforces other laws, notably Section 361 of the Public Health Service Act as well as associated regulations. Much of this regulatory-enforcement work is ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Batch Production
Batch production is a method of manufacturing in which products are made as specified groups or amounts, within a time frame. A batch can go through a series of steps in a large manufacturing process to make the final desired product. Batch production is used for many types of manufacturing that may need smaller amounts of production at a time to ensure specific quality standards or changes in the process. This is opposed to large mass production Mass production, also known as mass production, series production, series manufacture, or continuous production, is the production of substantial amounts of standardized products in a constant flow, including and especially on assembly lines ... or continuous production methods, where the product or process does not need to be checked or changed as frequently or periodically. Characteristics In the manufacturing batch production process, the machines are in chronological order directly related to the manufacturing process. The ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mill (grinding)
A mill is a device, often a structure, machine or kitchen appliance, that breaks solid materials into smaller pieces by grinding, crushing, or cutting. Such comminution is an important unit operation in many processes. There are many different types of mills and many types of materials processed in them. Historically, mills were powered by hand or by animals (e.g., via a hand crank), working animal (e.g., horse mill), wind ( windmill) or water (watermill). In the modern era, they are usually powered by electricity. The grinding of solid materials occurs through mechanical forces that break up the structure by overcoming the interior bonding forces. After the grinding the state of the solid is changed: the grain size, the grain size disposition and the grain shape. Milling also refers to the process of breaking down, separating, sizing, or classifying aggregate material (e.g. mining ore). For instance rock crushing or grinding to produce uniform aggregate size for construc ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |