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Formulation
Formulation is a term used in various senses in various applications, both the material and the abstract or formal. Its fundamental meaning is the putting together of components in appropriate relationships or structures, according to a formula. Etymologically ''formula'' is the diminutive of the Latin ''forma'', meaning shape. In that sense a ''formulation'' is created according to the standard for the product. Abstract applications Disciplines in which one might use the word ''formulation'' in the abstract sense include logic, mathematics, linguistics, legal theory, and computer science. For details, see the related articles. Material applications In more material senses the concept of ''formulation'' appears in the physical sciences, such as physics, chemistry, and biology. It also is ubiquitous in industry, engineering and medicine, especially pharmaceutics. Pharmacy In pharmacy, a formulation is a mixture or a structure such as a capsule, tablet, or an emulsion ...
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Pharmaceutical Formulation
Pharmaceutical formulation, in pharmaceutics, is the process in which different chemical substances, including the active drug, are combined to produce a final medicinal product. The word ''formulation'' is often used in a way that includes dosage form. Stages and timeline Formulation studies involve developing a preparation of the drug which is both stable and acceptable to the patients. For orally administered drugs, this usually involves incorporating the drug into a tablet or a capsule. It is important to make the distinction that a tablet contains a variety of other potentially inert substances apart from the drug itself, and studies have to be carried out to ensure that the encapsulated drug is compatible with these other substances in a way that does not cause harm, whether direct or indirect. Preformulation involves the characterization of a drug's physical, chemical, and mechanical properties in order to choose what other ingredients ( excipients) should be used in t ...
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Coating
A coating is a covering that is applied to the surface of an object, or substrate. The purpose of applying the coating may be decorative, functional, or both. Coatings may be applied as liquids, gases or solids e.g. powder coatings. Paints and lacquers are coatings that mostly have dual uses, which are protecting the substrate and being decorative, although some artists paints are only for decoration, and the paint on large industrial pipes is for identification (e.g. blue for process water, red for fire-fighting control) in addition to preventing corrosion. Along with corrosion resistance, functional coatings may also be applied to change the surface properties of the substrate, such as adhesion, wettability, or wear resistance.Howarth G.A "Synthesis of a legislation compliant corrosion protection coating system based on urethane, oxazolidine and waterborne epoxy technology" Master of Science Thesis April 1997 Imperial College London In other cases the coating adds a co ...
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Supersaturation
In physical chemistry, supersaturation occurs with a solution (chemistry), solution when the concentration of a solute exceeds the concentration specified by the value of solubility at Solubility equilibrium, equilibrium. Most commonly the term is applied to a solution of a solid in a liquid, but it can also be applied to liquids and gases dissolved in a liquid. A supersaturated solution is in a metastable state; it may return to equilibrium by separation process, separation of the excess of solute from the solution, by dilution of the solution by adding solvent, or by increasing the solubility of the solute in the solvent. History Early studies of the phenomenon were conducted with sodium sulfate, also known as Glauber's Salt because, unusually, the solubility of this salt in water may decrease with increasing temperature. Early studies have been summarised by Tomlinson. It was shown that the crystallization of a supersaturated solution does not simply come from its agitation ...
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Lubricant
A lubricant (sometimes shortened to lube) is a substance that helps to reduce friction between surfaces in mutual contact, which ultimately reduces the heat generated when the surfaces move. It may also have the function of transmitting forces, transporting foreign particles, or heating or cooling the surfaces. The property of reducing friction is known as lubricity. In addition to industrial applications, lubricants are used for many other purposes. Other uses include cooking (oils and fats in use in frying pans and baking to prevent food sticking), to reduce rusting and friction in machinery, through the use of motor oil and Grease (lubricant), grease, bioapplications on humans (e.g., lubricants for Replacement joint, artificial joints), ultrasound examination, medical examination, and sexual intercourse. It is mainly used to reduce friction and to contribute to a better, more efficient functioning of a mechanism. History Lubricants have been in some use for thousands of year ...
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Cleaning Agent
Cleaning agents or hard-surface cleaners are substances (usually liquids, powders, sprays, or granules) used to remove dirt, including dust, stains, foul odors, and clutter on surfaces. Purposes of cleaning agents include health, beauty, removing offensive odors, and avoiding the spread of dirt and contaminants to oneself and others. Some cleaning agents can kill bacteria (e.g. door handle bacteria, as well as bacteria on worktops and other metallic surfaces) and clean at the same time. Others, called degreasers, contain organic solvents to help dissolve oils and fats. Chemical agents Acidic Acidic cleaning agents are mainly used for removal of deposits like fouling, scaling. The active ingredients are normally strong mineral acids and Chelation, chelants. Often, surfactants and corrosion inhibitors are added to the acid. Hydrochloric acid is a common mineral acid typically used for concrete. Vinegar can also be used to clean hard surfaces and remove calcium deposits. Sulphuric ...
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Tablet (pharmacy)
A tablet (also known as a pill) is a pharmaceutical oral dosage form (''oral solid dosage'', or OSD) or solid unit dosage form. Tablets may be defined as the solid unit dosage form of medication with suitable excipients. It comprises a mixture of active substances and excipients, usually in powder form, that are pressed or compacted into a solid dose. The main advantages of tablets are that they ensure a consistent dose of medicine that is easy to consume. Tablets are prepared either by moulding or by compression. The excipients can include diluents, binders or granulating agents, glidants (flow aids) and lubricants to ensure efficient tabletting; disintegrants to promote tablet break-up in the digestive tract; sweeteners or flavours to enhance taste; and pigments to make the tablets visually attractive or aid in visual identification of an unknown tablet. A polymer coating is often applied to make the tablet smoother and easier to swallow, to control the release rate ...
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Food
Food is any substance consumed by an organism for Nutrient, nutritional support. Food is usually of plant, animal, or Fungus, fungal origin and contains essential nutrients such as carbohydrates, fats, protein (nutrient), proteins, vitamins, or Mineral (nutrient), minerals. The substance is Ingestion, ingested by an organism and assimilated by the organism's Cell (biology), cells to provide energy, maintain life, or stimulate growth. Different species of animals have different List of feeding behaviours, feeding behaviours that satisfy the needs of their metabolisms and have evolved to fill a specific ecological niche within specific geographical contexts. Omnivore, Omnivorous humans are highly adaptable and have adapted to obtaining food in many different ecosystems. Humans generally use cooking to prepare food for consumption. The majority of the food energy required is supplied by the industrial food industry, which produces food through Intensive farming, intensive agricu ...
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Alloy
An alloy is a mixture of chemical elements of which in most cases at least one is a metal, metallic element, although it is also sometimes used for mixtures of elements; herein only metallic alloys are described. Metallic alloys often have properties that differ from those of the pure elements from which they are made. The vast majority of metals used for commercial purposes are alloyed to improve their properties or behavior, such as increased strength, hardness or corrosion resistance. Metals may also be alloyed to reduce their overall cost, for instance alloys of gold and Copper(II) sulfate, copper. A typical example of an alloy is SAE 304 stainless steel, 304 grade stainless steel which is commonly used for kitchen utensils, pans, knives and forks. Sometime also known as 18/8, it as an alloy consisting broadly of 74% iron, 18% chromium and 8% nickel. The chromium and nickel alloying elements add strength and hardness to the majority iron element, but their main function is ...
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Cosmetics
Cosmetics are substances that are intended for application to the body for cleansing, beautifying, promoting attractiveness, or altering appearance. They are mixtures of chemical compounds derived from either Natural product, natural sources or created synthetically. Cosmetics have various purposes, including personal care, personal and skin care. They can also be used to conceal blemishes and enhance natural features (such as the eyebrows and eyelashes). Makeup can also add colour to a person's face, enhance a person's features or change the appearance of the face entirely to resemble a different person, creature, or object. People have used cosmetics for thousands of years for skin care and appearance enhancement. Visible cosmetics for both women and men have gone in and out of fashion over the centuries. Some early forms of cosmetics contained harmful ingredients such as lead that caused serious health problems and sometimes resulted in death. Modern commercial cosmetic ...
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Drug
A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. Consumption of drugs can be via insufflation (medicine), inhalation, drug injection, injection, smoking, ingestion, absorption (skin), absorption via a dermal patch, patch on the skin, suppository, or sublingual administration, dissolution under the tongue. In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect. A pharmaceutical drug, also called a medication or medicine, is a chemical substance used to pharmacotherapy, treat, cure, preventive healthcare, prevent, or medical diagnosis, diagnose a disease or to promote well-being. Traditionally drugs were obtained through extraction from medicinal plants, but more recently also by organic synthesis. Pharmaceutical drugs may be used for a limited duration, or on a re ...
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Emulsion
An emulsion is a mixture of two or more liquids that are normally Miscibility, immiscible (unmixable or unblendable) owing to liquid-liquid phase separation. Emulsions are part of a more general class of two-phase systems of matter called colloids. Although the terms ''colloid'' and ''emulsion'' are sometimes used interchangeably, ''emulsion'' should be used when both phases, dispersed and continuous, are liquids. In an emulsion, one liquid (the dispersed phase (matter), phase) is dispersion (chemistry), dispersed in the other (the continuous phase). Examples of emulsions include vinaigrettes, homogenized milk, liquid biomolecular condensates, and some cutting fluids for metal working. Two liquids can form different types of emulsions. As an example, oil and water can form, first, an oil-in-water emulsion, in which the oil is the dispersed phase, and water is the continuous phase. Second, they can form a water-in-oil emulsion, in which water is the dispersed phase and oil is the ...
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Capsule (pharmacy)
In the manufacture of pharmaceuticals, encapsulation refers to a range of dosage forms—techniques used to enclose medicines—in a relatively stable shell known as a capsule, allowing them to, for example, be taken orally or be used as suppositories. The two main types of capsules are: * Hard-shelled capsules, which contain dry, powdered ingredients or miniature pellets made by ''e.g.'' processes of extrusion or spheronization. These are made in two-halves: a smaller-diameter "body" that is filled and then sealed using a larger-diameter "cap". * Soft-shelled capsules, primarily used for oils and for active ingredients that are dissolved or suspended in oil. Both of these classes of capsules are made from aqueous solutions of gelling agents, such as animal protein (mainly gelatin) or plant polysaccharides or their derivatives (such as carrageenans and modified forms of starch and cellulose). Other ingredients can be added to the gelling agent solution including plasticizers ...
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