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Diplomonad
The diplomonads (Greek for "two units") are a group of flagellates, most of which are parasitic. They include ''Giardia duodenalis'', which causes giardiasis in humans. They are placed among the metamonads, and appear to be particularly close relatives of the retortamonads. Most diplomonads are double cells: they have two nuclei, each with four associated flagella, arranged symmetrically about the body's main axis. Like the retortamonads, they lack both mitochondria and Golgi apparatuses. However, they are now known to possess modified mitochondria, in the case of ''G. duodenalis'', called mitosomes. These are not used in ATP synthesis the way mitochondria are, but are involved in the maturation of iron-sulfur proteins. Possible sexual reproduction in ''Giardia'' The common intestinal parasite ''Giardia duodenalis'' (synonyms ''Giardia lamblia'', ''G. intestinalis'') was once considered to be a descendant of a protist lineage that predated the emergence of meiosis and sex ...
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Retortamonad
The retortamonads are a small group of flagellates, most commonly found in the intestines of animals as commensals, although a free-living species called the ''Chilomastix cuspidata'' exists. They are grouped under the taxon, Archezoa. They are usually around 5-20 μm in length, and all of their small subunit ribosomal RNA gene sequences are very similar to each other. There are two genera: ''Retortamonas'' with two flagella, and ''Chilomastix'' with four. In both cases there are four basal bodies anterior to a prominent feeding groove, and one flagellum is directed back through the cell, emerging from the groove. The retortamonads lack mitochondria, golgi apparatus, dictyosomes, and peroxisomes. They are close relatives of the diplomonads, and are placed among the metamonad The metamonads are microscopic eukaryotic organisms, a large group of flagellate amitochondriate Loukozoa. Their composition is not entirely settled, but they include the retortamonads, diplomonads ...
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Hexamitinae
''Hexamita'' is a genus of parasitic diplomonads. It is related to '' Giardia''. ''H. columbae'' and ''H. meleagridis'' live in the intestines of birds. ''H. muris'' and ''H. pitheci'' live in the intestines of mammals. ''H. salmonis'' and ''H. truttae'' live in the intestines of fish. The genus also includes the species ''Hexamita inflata ''Hexamita'' is a genus of parasitic Parasitism is a close relationship between species, where one organism, the parasite, lives on or inside another organism, the host, causing it some harm, and is adapted structurally to this way o ...''. It is believed that ''Hexamita'' parasites are one possible cause for head and lateral line erosion ("hole-in-the-head disease") in aquarium fishes. References External links * http://medical-dictionary.thefreedictionary.com/Hexamita * * http://www.lexic.us/definition-of/Hexamita Metamonads {{parasite-stub ...
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Metamonad
The metamonads are microscopic eukaryotic organisms, a large group of flagellate amitochondriate Loukozoa. Their composition is not entirely settled, but they include the retortamonads, diplomonads, and possibly the parabasalids and oxymonads as well. These four groups are all anaerobic (many being aerotolerant anerobes), occurring mostly as symbiotes or parasites of animals, as is the case with ''Giardia lamblia'' which causes diarrhea in mammals. Characteristics A number of parabasalids and oxymonads are found in termite guts, and play an important role in breaking down the cellulose found in wood. Some other metamonads are parasites. These flagellates are unusual in lacking mitochondria. Originally they were considered among the most primitive eukaryotes, diverging from the others before mitochondria appeared. However, they are now known to have lost mitochondria secondarily, and retain both organelles and nuclear genes derived from them. Mitochondrial relics include h ...
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Flagellate
A flagellate is a cell or organism with one or more whip-like appendages called flagella. The word ''flagellate'' also describes a particular construction (or level of organization) characteristic of many prokaryotes and eukaryotes and their means of motion. The term presently does not imply any specific relationship or classification of the organisms that possess flagella. However, the term "flagellate" is included in other terms (such as "dinoflagellate" and "choanoflagellata") which are more formally characterized. Form and behavior Flagella in eukaryotes are supported by microtubules in a characteristic arrangement, with nine fused pairs surrounding two central singlets. These arise from a basal body. In some flagellates, flagella direct food into a cytostome or mouth, where food is ingested. Flagella often support hairs, called mastigonemes, or contain rods. Their ultrastructure plays an important role in classifying eukaryotes. Among protoctists and microscopic anima ...
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Hexamita
''Hexamita'' is a genus of parasitic diplomonads. It is related to ''Giardia''. ''H. columbae'' and ''H. meleagridis'' live in the intestines of birds. ''H. muris'' and ''H. pitheci'' live in the intestines of mammals. ''H. salmonis'' and ''H. truttae'' live in the intestines of fish. The genus also includes the species ''Hexamita inflata ''Hexamita'' is a genus of parasitic diplomonads. It is related to ''Giardia''. ''H. columbae'' and ''H. meleagridis'' live in the intestines of birds. ''H. muris'' and ''H. pitheci'' live in the intestines of mammals. ''H. salmonis'' and ''H. ...''. It is believed that ''Hexamita'' parasites are one possible cause for head and lateral line erosion ("hole-in-the-head disease") in aquarium fishes. References External links * http://medical-dictionary.thefreedictionary.com/Hexamita * * http://www.lexic.us/definition-of/Hexamita Metamonads {{parasite-stub ...
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Giardiinae
Giardiinae is a sub-family of diplomonad The diplomonads (Greek for "two units") are a group of flagellates, most of which are parasitic. They include ''Giardia duodenalis'', which causes giardiasis in humans. They are placed among the metamonads, and appear to be particularly close r ...s. References {{Taxonbar, from=Q1522762 Excavata families ...
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Giardia
''Giardia'' ( or ) is a genus of anaerobic flagellated protozoan parasites of the phylum Metamonada that colonise and reproduce in the small intestines of several vertebrates, causing the disease giardiasis. Their life cycle alternates between a swimming trophozoite and an infective, resistant cyst. ''Giardia'' were first described by the Dutch microscopist Antonie van Leeuwenhoek in 1681. The genus is named after French zoologist Alfred Mathieu Giard. Characteristics Like other diplomonads, ''Giardia'' have two nuclei, each with four associated flagella, and were thought to lack both mitochondria and Golgi apparatuses. However, they are now known to possess a complex endomembrane system as well as mitochondrial remnants, called mitosomes, through mitochondrial reduction. The mitosomes are not used in ATP synthesis the way mitochondria are, but are involved in the maturation of iron-sulfur proteins. The synapomorphies of genus ''Giardia'' include cells with duplicate org ...
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Karyogamy
Karyogamy is the final step in the process of fusing together two haploid eukaryotic cells, and refers specifically to the fusion of the two nuclei. Before karyogamy, each haploid cell has one complete copy of the organism's genome. In order for karyogamy to occur, the cell membrane and cytoplasm of each cell must fuse with the other in a process known as plasmogamy. Once within the joined cell membrane, the nuclei are referred to as pronuclei. Once the cell membranes, cytoplasm, and pronuclei fuse, the resulting single cell is diploid, containing two copies of the genome. This diploid cell, called a zygote or zygospore can then enter meiosis (a process of chromosome duplication, recombination, and division, to produce four new haploid cells), or continue to divide by mitosis. Mammalian fertilization uses a comparable process to combine haploid sperm and egg cells (gametes) to create a diploid fertilized egg. The term karyogamy comes from the Greek ''karyo-'' (from κάρυον '' ...
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Homologous Recombination
Homologous recombination is a type of genetic recombination in which genetic information is exchanged between two similar or identical molecules of double-stranded or single-stranded nucleic acids (usually DNA as in cellular organisms but may be also RNA in viruses). Homologous recombination is widely used by cells to accurately DNA repair harmful breaks that occur on both strands of DNA, known as double-strand breaks (DSB), in a process called homologous recombinational repair (HRR). Homologous recombination also produces new combinations of DNA sequences during meiosis, the process by which eukaryotes make gamete cells, like sperm and egg cells in animals. These new combinations of DNA represent genetic variation in offspring, which in turn enables populations to adapt during the course of evolution. Homologous recombination is also used in horizontal gene transfer to exchange genetic material between different strains and species of bacteria and viruses. Horizontal ...
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Mitosome
A mitosome is an organelle found in some unicellular eukaryotic organisms, like in members of the supergroup Excavata. The mitosome was found and named in 1999, and its function has not yet been well characterized. It was termed a ''crypton'' by one group, but that name is no longer in use. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria. These organisms do not have the capability of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria. The mitosome was first described in ''Entamoeba histolytica,'' an intestinal parasite of humans. Mitosomes have also been identified in several species of Microsporidia and in ''Giardia intestinalis''. Origin and function Mitosomes are almost certainly derived from mitochondria. Like mitochondria, they have a double membrane and most proteins are delivered to them by a targeting sequence of amino acids. The targeting sequence is similar to that used ...
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Cell Nucleus
The cell nucleus (pl. nuclei; from Latin or , meaning ''kernel'' or ''seed'') is a membrane-bound organelle found in eukaryotic cells. Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells, have no nuclei, and a few others including osteoclasts have many. The main structures making up the nucleus are the nuclear envelope, a double membrane that encloses the entire organelle and isolates its contents from the cellular cytoplasm; and the nuclear matrix, a network within the nucleus that adds mechanical support. The cell nucleus contains nearly all of the cell's genome. Nuclear DNA is often organized into multiple chromosomes – long stands of DNA dotted with various proteins, such as histones, that protect and organize the DNA. The genes within these chromosomes are structured in such a way to promote cell function. The nucleus maintains the integrity of genes and controls the activities of the cell by regulating gene expres ...
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Eukaryote
Eukaryotes () are organisms whose cells have a nucleus. All animals, plants, fungi, and many unicellular organisms, are Eukaryotes. They belong to the group of organisms Eukaryota or Eukarya, which is one of the three domains of life. Bacteria and Archaea (both prokaryotes) make up the other two domains. The eukaryotes are usually now regarded as having emerged in the Archaea or as a sister of the Asgard archaea. This implies that there are only two domains of life, Bacteria and Archaea, with eukaryotes incorporated among archaea. Eukaryotes represent a small minority of the number of organisms, but, due to their generally much larger size, their collective global biomass is estimated to be about equal to that of prokaryotes. Eukaryotes emerged approximately 2.3–1.8 billion years ago, during the Proterozoic eon, likely as flagellated phagotrophs. Their name comes from the Greek εὖ (''eu'', "well" or "good") and κάρυον (''karyon'', "nut" or "kernel"). Euka ...
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