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Cohort Studies
A cohort study is a particular form of longitudinal study that samples a cohort (a group of people who share a defining characteristic, typically those who experienced a common event in a selected period, such as birth or graduation), performing a cross-section at intervals through time. It is a type of panel study where the individuals in the panel share a common characteristic. Cohort studies represent one of the fundamental designs of epidemiology which are used in research in the fields of medicine, pharmacy, nursing, psychology, social science, and in any field reliant on 'difficult to reach' answers that are based on evidence (statistics). In medicine for instance, while clinical trials are used primarily for assessing the safety of newly developed pharmaceuticals before they are approved for sale, epidemiological analysis on how risk factors affect the incidence of diseases is often used to identify the causes of diseases in the first place, and to help provide pre-clinica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Longitudinal Study
A longitudinal study (or longitudinal survey, or panel study) is a research design that involves repeated observations of the same variables (e.g., people) over short or long periods of time (i.e., uses longitudinal data). It is often a type of observational study, although it can also be structured as longitudinal randomized experiment. Longitudinal studies are often used in social-personality and clinical psychology, to study rapid fluctuations in behaviors, thoughts, and emotions from moment to moment or day to day; in developmental psychology, to study developmental trends across the life span; and in sociology, to study life events throughout lifetimes or generations; and in consumer research and political polling to study consumer trends. The reason for this is that, unlike cross-sectional studies, in which different individuals with the same characteristics are compared, longitudinal studies track the same people, and so the differences observed in those people are less l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Attrition (medicine, Epidemiology)
In science, attrition are ratios regarding the loss of participants during an experiment. Attrition rates are values that indicate the participant drop out. Higher attrition rates are found in longitudinal studies. See also * Intention-to-treat analysis In medicine an intention-to-treat (ITT) analysis of the results of a randomized controlled trial is based on the initial treatment assignment and not on the treatment eventually received. ITT analysis is intended to avoid various misleading artifac ... * Selection bias#Attrition Further reading * * {{cite book , first=Jeffrey M. , last=Wooldridge , title=Econometric Analysis of Cross Section and Panel Data , location=Cambridge , publisher=MIT Press , year=2010 , pages=837–842 , url=https://books.google.com/books?id=hSs3AgAAQBAJ&pg=PA837 , isbn=9780262296793 Experiments ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford University Press
Oxford University Press (OUP) is the university press of the University of Oxford. It is the largest university press in the world, and its printing history dates back to the 1480s. Having been officially granted the legal right to print books by decree in 1586, it is the second oldest university press after Cambridge University Press. It is a department of the University of Oxford and is governed by a group of 15 academics known as the Delegates of the Press, who are appointed by the vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, opposite Somerville College, in the inner suburb of Jericho. For the last 500 years, OUP has primarily focused on the publication of pedagogical texts an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Journal Of Epidemiology
The ''International Journal of Epidemiology'' is a bimonthly peer-reviewed medical journal covering research in epidemiology. It is the official journal of the International Epidemiological Association and is published by Oxford University Press. The journal is a member of the Committee on Publication Ethics. The editor-in-chief is Stephen Leeder (University of Sydney). History The journal was established in 1972 by the International Epidemiological Association to facilitate communication among its members and all those engaged in research, teaching and the application of epidemiology. The first editor-in-chief, Walter W. Holland, hoped to "overcome some of the problems of publication of epidemiological work in local journals, which often tend to be unavailable to workers outside that country" and to "create an international viewpoint of health problems." Editors The following persons are or have been editors-in-chief: *1972–1977: Walter W. Holland *1978–1981: A.E. Bennett ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dunedin
Dunedin ( ; mi, Ōtepoti) is the second-largest city in the South Island of New Zealand (after Christchurch), and the principal city of the Otago region. Its name comes from , the Scottish Gaelic name for Edinburgh, the capital of Scotland. The city has a rich Scottish, Chinese and Māori heritage. With an estimated population of as of , Dunedin is both New Zealand's seventh-most populous metro and urban area. For historic, cultural and geographic reasons the city has long been considered one of New Zealand's four main centres. The urban area of Dunedin lies on the central-eastern coast of Otago, surrounding the head of Otago Harbour, and the harbour and hills around Dunedin are the remnants of an extinct volcano. The city suburbs extend out into the surrounding valleys and hills, onto the isthmus of the Otago Peninsula, and along the shores of the Otago Harbour and the Pacific Ocean. Archaeological evidence points to lengthy occupation of the area by Māori prior to the a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dunedin Longitudinal Study
The Dunedin Multidisciplinary Health and Development Study (also known as the Dunedin Study) is a detailed study of human health, development and behaviour. Based at the University of Otago in New Zealand, the Dunedin Study has followed the lives of 1037 babies born between 1 April 1972 and 31 March 1973 at Dunedin's Queen Mary Maternity Hospital since their birth. Teams of national and international collaborators work on the Dunedin Study, including a team at Duke University in the United States. The research is constantly evolving to encompass research made possible by new technology and seeks to answer questions about how people's early years impact mental and physical health as they age. The study is now in its fifth decade and has produced over 1300 publications and reports, many of which have influenced or helped inform policy makers in New Zealand and overseas; many of these can be found on the publications section of their website. History The Dunedin Study was the ide ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British Birth Cohort Studies
Birth cohort studies in Britain include four long-term medical and social studies, carried out over the lives of a group of participants, from birth. Two of these studies have continued for over 50 years. Principal cohort studies * National Survey of Health & Development (NSHD), established in 1946 * National Child Development Study (NCDS), established in 1958 * 1970 British Cohort Study (BCS70) * Millennium Cohort Study (MCS), established in 2000 Methods and outcomes The studies involve repeated surveys of large numbers of individuals (typically around 17,000) from birth and throughout their lives. They have collected information on education and employment, family and parenting, physical and mental health, and social attitudes, as well as applying cognitive tests at various ages. They are longitudinal studies that follow the same groups of people throughout their lives. As such, they enable research exploring how histories of health, wealth, education, family and employment ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Child Development Study
The National Child Development Study (NCDS) is a continuing, multi-disciplinary longitudinal study which follows the lives of 17,415 people born in England, Scotland and Wales from 17,205 women during the week of 3–9 March 1958. The results from this study helped reduce infant mortality and were instrumental in improving maternity services in the UK. History The origins of the NCDS can be found in the Perinatal Mortality Survey (PMS) which was then sponsored by the National Birthday Trust Fund and set up to collect information about the social and obstetric factors associated with stillbirth and death in early infancy.Catalogue - National Child Development Study: Sweep 8, 2008-2009 UK Data Service, University of Essex, retrieved September 21, 2009 The N ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Framingham Heart Study
The Framingham Heart Study is a long-term, ongoing cardiovascular cohort study of residents of the city of Framingham, Massachusetts. The study began in 1948 with 5,209 adult subjects from Framingham, and is now on its third generation of participants. Prior to the study almost nothing was known about the epidemiology of hypertensive or arteriosclerotic cardiovascular disease. Much of the now-common knowledge concerning heart disease, such as the effects of diet, exercise, and common medications such as aspirin, is based on this longitudinal study. It is a project of the National Heart, Lung, and Blood Institute, in collaboration with (since 1971) Boston University. Various health professionals from the hospitals and universities of Greater Boston staff the project. History In 1948, the study was commissioned by Congress, with a choice made between Framingham, Massachusetts and Paintsville, Kentucky. Framingham was chosen when residents showed more general interest in heart ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can va ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statistical Significance
In statistical hypothesis testing, a result has statistical significance when it is very unlikely to have occurred given the null hypothesis (simply by chance alone). More precisely, a study's defined significance level, denoted by \alpha, is the probability of the study rejecting the null hypothesis, given that the null hypothesis is true; and the ''p''-value of a result, ''p'', is the probability of obtaining a result at least as extreme, given that the null hypothesis is true. The result is statistically significant, by the standards of the study, when p \le \alpha. The significance level for a study is chosen before data collection, and is typically set to 5% or much lower—depending on the field of study. In any experiment or observation that involves drawing a sample from a population, there is always the possibility that an observed effect would have occurred due to sampling error alone. But if the ''p''-value of an observed effect is less than (or equal to) the significa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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