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Candyflipping
Polysubstance use or multisubstance use is the use of combinations of psychoactive substances with both legal and illegal substances. This page lists polysubstance combinations that are entheogenic, recreational, or off-label indicated use of pharmaceuticals. For example, the over-the-counter motion sickness combination drug dimenhydrinate ( 8-chlorotheophylline/diphenhydramine) is occasionally used in higher doses as a deliriant. The prescription medicine Adderall (dextroamphetamine sulfate/amphetamine sulfate/dextroamphetamine saccharate/amphetamine aspartate monohydrate) is also frequently used recreationally. However, using non-prescribed drugs, using non-prescribed dose regimen, can cause polysubstance dependence, or combined drug intoxication which may lead to deaths. Table To avoid an excessively long list, the table below only lists recreational drug combinations that are not patent medicine. See also * ACE mixture * Brompton cocktail * D-IX * Desbutal * Dexamyl ...
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Combo 2
The IEC 62196#IEC 62196-2, IEC 62196-2 Type 2 connector (sometimes referred to as Mennekes for the German company that designed it) is used for charging electric vehicles using AC power, mainly within Europe, Australia, NZ and many other countries outside of North America. The Type 2 connector was adopted as the EU standard in 2013, with full compliance required by 2025. The connector was chosen by the EU to promote electric mobility and ensure interoperability between different vehicles and charging stations. The Type 2 connector is equipped with seven pin connectors, which are used for communication between the vehicle and charger using the J1772 signaling protocol, and for either single or 3-phase AC power with a maximum voltage of 500 V, thereby delivering up to 43kW of power. A later, modified version of the Type 2 connector which includes two additional DC current pins at the base to allow for high-power (up to 350kW) DC fast charging, is known as a Combined Charging System ...
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List Of Deaths From Drug Overdose And Intoxication
Drug overdose and intoxication are significant causes of accidental death and can also be used as a form of suicide. Death can occur from overdosing on a single or multiple drugs, or from combined drug intoxication (CDI) due to poly drug use. Poly drug use often carries more risk than use of a single drug, due to an increase in side effects, and drug synergy. For example, the chance of death from overdosing on opiates is greatly increased when they are consumed in conjunction with alcohol. While they are two distinct phenomena, deaths from CDI are often misreported as overdoses. Drug overdoses and intoxication can also cause indirect deaths. For example, while marijuana does not cause fatal overdoses, being intoxicated by it can increase the chance of fatal traffic collisions. Drug use and overdoses increased significantly in the 1800s due to the commercialization and availability of certain drugs. For example, while opium and coca had been used for centuries, their active ingr ...
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Banisteriopsis Caapi
''Banisteriopsis caapi'', also known as, caapi, soul vine, yagé (yage), or ayahuasca (the latter of which also refers to the psychedelic decoction made with the vine and a plant source of dimethyltryptamine) is a South American liana of the family Malpighiaceae. It is commonly used as an ingredient of ayahuasca, a decoction with a long history of its entheogenic use and holds status as a "plant teacher" among the Indigenous peoples of the Amazon rainforest. It was used by Indigenous peoples of South America for centuries, but it was first documented by Europeans in the 16th century and formally identified by botanist Richard Spruce in 1851. According to ''The CRC World Dictionary of Plant Names'' by Umberto Quattrocchi, the naming of the genus '' Banisteriopsis'' was dedicated to John Banister, a 17th-century English clergyman and naturalist. An earlier name for the genus was ''Banisteria'' and the plant is sometimes referred to as ''Banisteria caapi''. Other names include ' ...
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Nicotine
Nicotine is a natural product, naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and ''Duboisia hopwoodii'') and is widely used recreational drug use, recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is used for smoking cessation to relieve drug withdrawal, withdrawal symptoms. Nicotine acts as a receptor agonist at most nicotinic acetylcholine receptors (nAChRs), except at two nicotinic receptor subunits (nAChRα9 and nAChRα10) where it acts as a receptor antagonist. Nicotine constitutes approximately 0.6–3.0% of the dry weight of tobacco. Nicotine is also present at Parts-per notation, ppb concentrations in edible plants in the family Solanaceae, including potatoes, tomatoes, and eggplants, though sources disagree on whether this has any biological significance to human consumers. It functions as an plant defense against herbivory, antiherbivore toxin; consequently, nicotine was widely used as an insecti ...
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Joint (cannabis)
A joint is a rolled Cannabis (drug), cannabis cigarette. Unlike commercial tobacco cigarettes, the user ordinarily hand-rolls joints with rolling papers, though in some cases they are machine-rolled. Rolling papers are the most common rolling medium in industrialized countries; however, brown paper, cigarettes or beedies with the tobacco removed, receipts and paper napkin can also be used, particularly in developing country, developing countries. Modern papers are manufactured in a range of sizes from a wide variety of materials including rice, hemp, and flax, and are also available in liquorice and other flavored varieties. Joint size can vary, typically containing between net weight of cannabis. Tobacco is sometimes used in the rolling process. Like smoking tobacco cannabis smoking is very dangerous to the health of the smoker, and may be dangerous to others like passive smoking. Variations and terminology Although joints by definition contain cannabis, regional diff ...
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Cannabis (drug)
Cannabis (), commonly known as marijuana (), weed, pot, and ganja, List of slang names for cannabis, among other names, is a non-chemically uniform psychoactive drug from the ''Cannabis'' plant. Native to Central or South Asia, cannabis has been used as a drug for both recreational and Entheogenic use of cannabis, entheogenic purposes and in various traditional medicines for centuries. Tetrahydrocannabinol (THC) is the main psychoactive component of cannabis, which is one of the 483 known compounds in the plant, including at least 65 other cannabinoids, such as cannabidiol (CBD). Cannabis can be used Cannabis smoking, by smoking, Vaporizer (inhalation device), vaporizing, Cannabis edible, within food, or Tincture of cannabis, as an extract. Cannabis has effects of cannabis, various mental and physical effects, which include euphoria, altered states of mind and Cannabis and time perception, sense of time, difficulty concentrating, Cannabis and memory, impaired short-term memo ...
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Polypharmacy
Polypharmacy (polypragmasia) is an umbrella term to describe the simultaneous use of multiple medicines by a patient for their conditions. The term polypharmacy is often defined as regularly taking five or more medicines but there is no standard definition and the term has also been used in the context of when a person is prescribed 2 or more medications at the same time. Polypharmacy may be the consequence of having multiple long-term conditions, also known as multimorbidity and is more common in the elderly. In some cases, an excessive number of medications at the same time is worrisome, especially for people who are older with many chronic health conditions, because this increases the risk of an adverse event in that population. In many cases, polypharmacy cannot be avoided, but 'appropriate polypharmacy' practices are encouraged to decrease the risk of adverse effects. Appropriate polypharmacy is defined as the practice of prescribing for a person who has multiple conditions or ...
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Pharmaceutical
Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy ( pharmacotherapy) is an important part of the medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are classified in many ways. One of the key divisions is by level of control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the medical prescription) from over-the-counter drugs (those that consumers can order for themselves). Medicines may be classified by mode of action, route of administration, biological system affected, or therapeutic effects. The World Health Organization keeps a list of essential medicines. Drug discovery and drug development are complex and expensive endeavors undertaken by pharmaceutical companies, academic scientists, and government ...
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Speedball (drug)
Speedball, powerball, or over and under is the polydrug mixture of a stimulant with a depressant, usually an opioid. The most well-known mixture used for recreational drug use is that of cocaine and heroin; however, amphetamines can also be mixed with morphine and/or fentanyl. A speedball may be taken intravenously or by nasal insufflation. Speedballs often give stronger effects than either drug when taken alone due to drug synergy, and are a particularly hazardous mixture that can easily cause heart attack, respiratory arrest and death. When compared to single drugs, speedballs are more likely to lead to addiction, relapse and overdose. History The classic speedball is heroin and cocaine. It could also mean morphine and an amphetamine. The United States Drug Enforcement Administration warned in 2019 that the rapid rise of fentanyl supply in the country has led to combinations of both fentanyl and heroin with cocaine ("super speedballs"). In addition, the cross-contamination ...
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Stimulant
Stimulants (also known as central nervous system stimulants, or psychostimulants, or colloquially as uppers) are a class of drugs that increase alertness. They are used for various purposes, such as enhancing attention, motivation, cognition, Mood disorder, mood, and physical activity, physical performance. Some stimulants occur naturally, while others are exclusively synthetic. Common stimulants include caffeine, nicotine, amphetamines, cocaine, methylphenidate, and modafinil. Stimulants may be subject to varying forms of regulation, or outright prohibition, depending on jurisdiction. Stimulants increase activity in the sympathetic nervous system, either directly or indirectly. Prototypical stimulants increase synaptic concentrations of neurotransmitter, excitatory neurotransmitters, particularly norepinephrine and dopamine (e.g., methylphenidate). Other stimulants work by binding to the Receptor (biochemistry), receptors of excitatory neurotransmitters (e.g., nicotine) or by ...
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Depressant
Depressants, also known as central nervous system depressants, or colloquially known as "downers", are drugs that lower neurotransmission levels, decrease the electrical activity of brain cells, or reduce arousal or stimulation in various areas of the brain. Some specific depressants do influence mood, either positively (e.g., opioids) or negatively, but depressants often have no clear impact on mood (e.g., most anticonvulsants). In contrast, stimulants, or "uppers", increase mental alertness, making stimulants the opposite drug class from depressants. Antidepressants are defined by their effect on mood, not on general brain activity, so they form an orthogonal category of drugs. Depressants are closely related to sedatives as a category of drugs, with significant overlap. The terms may sometimes be used interchangeably or may be used in somewhat different contexts. Depressants are widely used throughout the world as prescription medicines and illicit substances. A ...
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