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Calcium Phosphate
The term calcium phosphate refers to a family of materials and minerals containing calcium ions (Ca2+) together with inorganic phosphate anions. Some so-called calcium phosphates contain oxide and hydroxide as well. Calcium phosphates are white solids of nutritional value and are found in many living organisms, e.g., bone mineral and tooth enamel. In milk, it exists in a colloidal form in micelles bound to casein protein with magnesium, zinc, and citrate–collectively referred to as colloidal calcium phosphate (CCP). Various calcium phosphate minerals, which often are not white owing to impurities, are used in the production of phosphoric acid and fertilizers. Overuse of certain forms of calcium phosphate can lead to nutrient-containing surface runoff and subsequent adverse effects upon receiving waters such as algal blooms and eutrophication (over-enrichment with nutrients and minerals). Orthophosphates, di- and monohydrogen phosphates These materials contain Ca2+ combin ...
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Water
Water is an inorganic compound with the chemical formula . It is a transparent, tasteless, odorless, and Color of water, nearly colorless chemical substance. It is the main constituent of Earth's hydrosphere and the fluids of all known living organisms (in which it acts as a solvent). It is vital for all known forms of life, despite not providing food energy or organic micronutrients. Its chemical formula, , indicates that each of its molecules contains one oxygen and two hydrogen atoms, connected by covalent bonds. The hydrogen atoms are attached to the oxygen atom at an angle of 104.45°. In liquid form, is also called "water" at standard temperature and pressure. Because Earth's environment is relatively close to water's triple point, water exists on Earth as a solid, a liquid, and a gas. It forms precipitation in the form of rain and aerosols in the form of fog. Clouds consist of suspended droplets of water and ice, its solid state. When finely divided, crystalline ice ...
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Nutrient
A nutrient is a substance used by an organism to survive, grow and reproduce. The requirement for dietary nutrient intake applies to animals, plants, fungi and protists. Nutrients can be incorporated into cells for metabolic purposes or excreted by cells to create non-cellular structures such as hair, scales, feathers, or exoskeletons. Some nutrients can be metabolically converted into smaller molecules in the process of releasing energy such as for carbohydrates, lipids, proteins and fermentation products ( ethanol or vinegar) leading to end-products of water and carbon dioxide. All organisms require water. Essential nutrients for animals are the energy sources, some of the amino acids that are combined to create proteins, a subset of fatty acids, vitamins and certain minerals. Plants require more diverse minerals absorbed through roots, plus carbon dioxide and oxygen absorbed through leaves. Fungi live on dead or living organic matter and meet nutrient needs from th ...
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Pyrophosphate
In chemistry, pyrophosphates are phosphorus oxyanions that contain two phosphorus atoms in a linkage. A number of pyrophosphate salts exist, such as disodium pyrophosphate () and tetrasodium pyrophosphate (), among others. Often pyrophosphates are called diphosphates. The parent pyrophosphates are derived from partial or complete neutralization of pyrophosphoric acid. The pyrophosphate bond is also sometimes referred to as a phosphoanhydride bond, a naming convention which emphasizes the loss of water that occurs when two phosphates form a new bond, and which mirrors the nomenclature for Organic acid anhydride, anhydrides of carboxylic acids. Pyrophosphates are found in Adenosine triphosphate, ATP and other nucleotide triphosphates, which are important in biochemistry. The term pyrophosphate is also the name of esters formed by the condensation of a phosphorylated biological compound with inorganic phosphate, as for dimethylallyl pyrophosphate. This bond is also referred to as a ...
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Polyphosphate
A polyphosphate is a Salt (chemistry), salt or ester of polymeric oxyanions formed from tetrahedral PO4 (phosphate) structural units linked together by sharing oxygen atoms. Polyphosphates can adopt linear or a cyclic (also called, ring) structures. In biology, the polyphosphate esters adenosine diphosphate, ADP and adenosine triphosphate, ATP are involved in energy storage. A variety of polyphosphates find application in mineral sequestration in municipal waters, generally being present at 1 to 5 ppm. guanosine triphosphate, GTP, cytidine triphosphate, CTP, and uridine triphosphate, UTP are also nucleotides important in the protein synthesis, lipid synthesis, and carbohydrate metabolism, respectively. Polyphosphates are also used as food additives, marked E452. Structure Image:Triphosphorsäure.svg, Structure of triphosphoric acid Image:Polyphosphoric acid.svg, Polyphosphoric acid Image:Trimetaphosphat.svg, Cyclic trimetaphosphate Image:Adenosindiphosphat protoni ...
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Amorphous Calcium Phosphate
In condensed matter physics and materials science, an amorphous solid (or non-crystalline solid) is a solid that lacks the long-range order that is a characteristic of a crystal. The terms "glass" and "glassy solid" are sometimes used synonymously with amorphous solid; however, these terms refer specifically to amorphous materials that undergo a glass transition. Examples of amorphous solids include glasses, metallic glasses, and certain types of plastics and polymers. Etymology The term "Amorphous" comes from the Greek ''a'' ("without"), and ''morphé'' ("shape, form"). Structure Amorphous materials have an internal structure of molecular-scale structural blocks that can be similar to the basic structural units in the crystalline phase of the same compound. Unlike in crystalline materials, however, no long-range regularity exists: amorphous materials cannot be described by the repetition of a finite unit cell. Statistical measures, such as the atomic density function and ...
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Octacalcium Phosphate
Octacalcium phosphate (sometimes referred to as OCP) is a form of calcium phosphate with formula . OCP may be a precursor to tooth enamel, dentine, and bones. OCP is a precursor of hydroxyapatite (HA), an inorganic biomineral that is important in bone growth. OCP has garnered lots of attention due to its inherent biocompatibility. While OCP exhibits good properties in terms of bone growth, very stringent synthesis requirements make it difficult for mass productions, but nevertheless has shown promise not only in-vitro, but also in in-vivo clinical case studies. Background Calcium phosphate was discovered by Johan Gottlieb in 1769, and since its discovery calcium phosphate has been widely researched and has been found to be one of the most important inorganic structures within hard tissue of vertebrates. Calcium phosphate has been used to treat various illnesses such as rickets, scrofula, diarrhea, ulcerations, and inflammation, but its applications in orthopedics and dentistry ...
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Whitlockite
Whitlockite is a mineral, an unusual form of calcium phosphate. Its formula is Ca9(Mg Fe)(PO4)6PO3O H. It is a relatively rare mineral but is found in granitic pegmatites, phosphate rock deposits, guano caves and in chondrite meteorites. It was first described in 1941 and named for Herbert Percy Whitlock (1868–1948), American mineralogist and curator at the American Museum of Natural History in New York City. With regards to periodontal dentistry, magnesium whitlockite comprises one component of many of the inorganic content of calculus. It is found primarily in subgingival calculus (as opposed to supragingival calculus). It is also found more in posterior as opposed to anterior regions of the oral cavity. Historical evolution as distinct minerals Whitlockite is a member of the phosphate group of minerals with three distinct occurrences. For many years, these occurrences were thought to be identical. However, recent studies using x-ray and electron diffraction have been a ...
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Tricalcium Phosphate
Tricalcium phosphate (sometimes abbreviated TCP), more commonly known as Calcium phosphate, is a calcium salt of phosphoric acid with the chemical formula Ca3(PO4)2. It is also known as tribasic calcium phosphate and bone phosphate of lime (BPL). It is a white solid of low solubility. Most commercial samples of "tricalcium phosphate" are in fact hydroxyapatite. It exists as three crystalline polymorphs α, α′, and β. The α and α′ states are stable at high temperatures. Nomenclature ''Calcium phosphate'' refers to numerous materials consisting of calcium ions (Ca2+) together with orthophosphates (), metaphosphates or pyrophosphates () and occasionally oxide and hydroxide ions. Especially, the common mineral apatite has formula Ca5(PO4)3''X'', where ''X'' is F, Cl, OH, or a mixture; it is hydroxyapatite if the extra ion is mainly hydroxide. Much of the "tricalcium phosphate" on the market is actually powdered hydroxyapatite. Preparation Tricalcium phosphate is produc ...
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Brushite
Brushite is a phosphate mineral with the chemical formula . Crystals of the pure compound belong to the monoclinic space group C2/c and are colorless.Brishite
Webmineral
It is the phosphate analogue of the pharmacolite.


Discovery and occurrence

Brushite was first described in 1865 as an occurrence on Aves Island, Nueva Esparta,

Dicalcium Phosphate
Dicalcium phosphate is the calcium phosphate with the formula CaHPO4 and its dihydrate. The "di" prefix in the common name arises because the formation of the HPO42– anion involves the removal of two protons from phosphoric acid, H3PO4. It is also known as dibasic calcium phosphate or calcium monohydrogen phosphate. Dicalcium phosphate is used as a food additive, and it is found in some toothpastes as a polishing agent and biomaterial. Preparation Dibasic calcium phosphate is produced by neutralizing calcium hydroxide with phosphoric acid, precipitating the dihydrate as a solid. At 60 °C the anhydrous form is precipitated: To prevent degradation that would form hydroxyapatite, sodium pyrophosphate or trimagnesium phosphate octahydrate are added when, for example, dibasic calcium phosphate dihydrate is to be used as a polishing agent in toothpaste. In a continuous process CaCl2 can be treated with (NH4)2HPO4 to form the dihydrate: A slurry of the dihydrate is then he ...
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Monocalcium Phosphate
Monocalcium phosphate is an inorganic compound with the chemical formula Ca(H2PO4)2 ("AMCP" or "CMP-A" for anhydrous monocalcium phosphate). It is commonly found as the monohydrate ("MCP" or "MCP-M"), Ca(H2PO4)2·H2O. Both salts are colourless solids. They are used mainly as superphosphate fertilizers and are also popular leavening agents. Preparation Material of relatively high purity, as required for baking, is produced by treating calcium hydroxide with phosphoric acid: Samples of Ca(H2PO4)2 tend to convert to dicalcium phosphate: Applications Use in fertilizers Superphosphate fertilizers are produced by treatment of " phosphate rock" with acids ("acidulation"). Using phosphoric acid, fluorapatite is converted to Ca(H2PO4)2: This solid is called triple superphosphate. Several million tons are produced annually for use as fertilizers. Using sulfuric acid, fluorapatite is converted to a mixture of Ca(H2PO4)2 and CaSO4. This solid is called single superphosphate. ...
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