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Blue Rose
A blue rose is a flower of the genus ''Rosa'' (family Rosaceae) that presents blue-to-violet pigmentation instead of the more common red, white, or yellow. Blue roses are often used to symbolize mystery or attaining the impossible. However, because of genetic limitations, they do not exist in nature. In 2004, researchers used genetic modification to create roses that contain the blue pigment delphinidin. So-called "blue roses" have been bred by conventional hybridization methods, but the results, such as "Blue Moon", are more accurately described as lilac in color. Dyed roses Since blue roses do not exist in nature, as roses lack the specific gene that has the ability to produce a "true blue" color, blue roses are traditionally created by dyeing white roses. In a book entitled ''Kitāb al-filāḥah'' written by Ibn al-'Awwām al-Ishbīlī in Arabic in the 12th century, and translated into French by J. J. Clement as ''Le livre de l'agriculture,'' there are references to azur ...
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Blue Rose-artificially Coloured
Blue is one of the three primary colours in the RYB colour model (traditional colour theory), as well as in the RGB (additive) colour model. It lies between violet and cyan on the spectrum of visible light. The eye perceives blue when observing light with a dominant wavelength between approximately 450 and 495 nanometres. Most blues contain a slight mixture of other colours; azure contains some green, while ultramarine contains some violet. The clear daytime sky and the deep sea appear blue because of an optical effect known as Rayleigh scattering. An optical effect called Tyndall effect explains blue eyes. Distant objects appear more blue because of another optical effect called aerial perspective. Blue has been an important colour in art and decoration since ancient times. The semi-precious stone lapis lazuli was used in ancient Egypt for jewellery and ornament and later, in the Renaissance, to make the pigment ultramarine, the most expensive of all pigments. In the ...
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RNA Interference
RNA interference (RNAi) is a biological process in which RNA molecules are involved in sequence-specific suppression of gene expression by double-stranded RNA, through translational or transcriptional repression. Historically, RNAi was known by other names, including ''co-suppression'', ''post-transcriptional gene silencing'' (PTGS), and ''quelling''. The detailed study of each of these seemingly different processes elucidated that the identity of these phenomena were all actually RNAi. Andrew Fire and Craig C. Mello shared the 2006 Nobel Prize in Physiology or Medicine for their work on RNAi in the nematode worm '' Caenorhabditis elegans'', which they published in 1998. Since the discovery of RNAi and its regulatory potentials, it has become evident that RNAi has immense potential in suppression of desired genes. RNAi is now known as precise, efficient, stable and better than antisense therapy for gene suppression. Antisense RNA produced intracellularly by an expression vector m ...
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A Song Of Ice And Fire
''A Song of Ice and Fire'' is a series of epic fantasy novels by the American novelist and screenwriter George R. R. Martin. He began the first volume of the series, ''A Game of Thrones'', in 1991, and it was published in 1996. Martin, who initially envisioned the series as a trilogy, has published five out of a planned seven volumes. The fifth and most recent volume of the series, ''A Dance with Dragons'', was published in 2011, six years after the publication of the preceding book, ''A Feast for Crows''. He is currently writing the sixth novel, ''The Winds of Winter''. A seventh novel, ''A Dream of Spring'', is planned. ''A Song of Ice and Fire'' takes place on the fictional continents Westeros and Essos. The point of view of each chapter in the story is a limited perspective of a range of characters growing from nine in the first novel, to 31 characters by the fifth novel. Three main stories interweave: a dynastic war among several families for control of Westeros, the risin ...
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The Gunman And Other Stories
''The Gunman and Other Stories'' is the seventh studio album by the English pop band Prefab Sprout. Released in June 2001, the album was the band's only release for the EMI Liberty label. Album history Following 1997 album ''Andromeda Heights'' and 1999 compilation ''38 Carat Collection'', Prefab Sprout conducted their first tour of the UK for 10 years. The success of the tour led singer and frontman Paddy McAloon to consider recording material for a new album. Rather than opting for "new" material, McAloon chose to record material he had previously given to other artists as a "tidying up operation", before moving on to newer material. Despite drummer Neil Conti's involvement in the tour (having originally departed from the band in 1992), the studio band operated with McAloon and his brother Martin as sole members. Fellow singer Wendy Smith was absent due to having given birth the previous year, and other work commitments with her music therapy career. The album was produc ...
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Jimmy Nail
James Michael Aloysius Bradford (born 16 March 1954), known as Jimmy Nail, is an English singer-songwriter, actor, film producer, and television writer. He played the role of Leonard "Oz" Osborne in the television show ''Auf Wiedersehen, Pet'' and the title role in ''Spender''. He also recorded a 1992 number one single, "Ain't No Doubt". His role as Agustin, the oily crooner in the 1996 film ''Evita'', gave him international recognition. Early life James Michael Aloysius Bradford was born in Newcastle upon Tyne to father Jimmy and mother Laura. His father was an Irish Catholic shipyard worker, amateur boxer, and professional footballer. He describes himself as an angry kid who was expelled from secondary school for setting fire to curtains. When he was 13, his sister, Shelagh, died at the age of 20. He later spent time drinking, fighting, and generally rebelling against authority. He was involved in a fight after a football match and was sent to prison. After being released he ...
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Paddy McAloon
Patrick Joseph McAloon (born 7 June 1957) is an English singer-songwriter and a founder of the band Prefab Sprout. Early life McAloon was born and grew up in Witton Gilbert in County Durham, England. He was trained to be a Catholic priest before deciding on a career in music. Career Prefab Sprout enjoyed considerable success in the 1980s and early 1990s. They peaked commercially with "The King of Rock 'N' Roll", which was a top ten single in the UK Singles Chart. In an interview with ''Rolling Stone'' during the '' Jordan: The Comeback'' world tour, McAloon stated he has never seen a positive royalty cheque for his work with Prefab Sprout Songs written by McAloon have also been recorded by Kylie Minogue ("If You Don't Love Me"), Cher ("The Gunman"), Wendy Matthews ("God Watch Over You" and "Ride"), Sondre Lerche ("Nightingales" – the song appeared in " From Langley Park to Memphis" and Lerche sang it with the Faces Down Quartet as a tribute to Prefab Sprout), Danny S ...
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Clouds (Joni Mitchell Album)
''Clouds'' is the second album by Canadian singer-songwriter Joni Mitchell, released on May 1, 1969, by Reprise Records. After releasing her debut album, ''Song to a Seagull'' (1968), to considerable exposure, Mitchell recorded ''Clouds'' at A&M Studios in Hollywood. She produced most of the album and painted a self-portrait for its cover artwork. (The red flower is a prairie lily, the provincial flower of Saskatchewan.) ''Clouds'' has subtle, unconventional harmonies and songs about lovers, among other themes. The album charted at number 22 in Canada and number 31 in the United States. It has been certified gold by the Recording Industry Association of America, for shipments of 500,000 copies in the US. ''Clouds'' was generally well received by music critics. Background After moving to New York City and signing to Reprise Records in 1967, Mitchell recorded her 1968 debut album ''Song to a Seagull'' with producer David Crosby. The album was a mostly acoustic set of songs, som ...
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Joni Mitchell
Roberta Joan "Joni" Mitchell ( Anderson; born November 7, 1943) is a Canadian-American musician, producer, and painter. Among the most influential singer-songwriters to emerge from the 1960s folk music circuit, Mitchell became known for her starkly personal lyrics and unconventional compositions, which grew to incorporate pop music, pop and jazz music, jazz influences. She has received many accolades, including ten Grammy Awards and induction into the Rock and Roll Hall of Fame in 1997. ''Rolling Stone'' called her "one of the greatest songwriters ever", and AllMusic has stated, "When the dust settles, Joni Mitchell may stand as the most important and influential female recording artist of the late 20th century". Mitchell began singing in small nightclubs in Saskatoon, Saskatchewan, and throughout western Canada, before moving on to the nightclubs of Toronto, Ontario. She moved to the United States and began touring in 1965. Some of her original songs ("Urge for Going", "Chelsea ...
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Pleurisy
Pleurisy, also known as pleuritis, is inflammation of the membranes that surround the lungs and line the chest cavity (pleurae). This can result in a sharp chest pain while breathing. Occasionally the pain may be a constant dull ache. Other symptoms may include shortness of breath, cough, fever, or weight loss, depending on the underlying cause. The most common cause is a viral infection. Other causes include bacterial infection, pneumonia, pulmonary embolism, autoimmune disorders, lung cancer, following heart surgery, pancreatitis and asbestosis. Occasionally the cause remains unknown. The underlying mechanism involves the rubbing together of the pleurae instead of smooth gliding. Other conditions that can produce similar symptoms include pericarditis, heart attack, cholecystitis, pulmonary embolism, and pneumothorax. Diagnostic testing may include a chest X-ray, electrocardiogram (ECG), and blood tests. Treatment depends on the underlying cause. Paracetamol (acetaminop ...
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The Glass Menagerie
''The Glass Menagerie'' is a memory play by Tennessee Williams that premiered in 1944 and catapulted Williams from obscurity to fame. The play has strong autobiographical elements, featuring characters based on its author, his Histrionic personality disorder, histrionic mother, and his mentally fragile sister. In writing the play, Williams drew on an earlier short story, as well as a screenplay he had written under the title of ''The Gentleman Caller''. The play premiered in Chicago in 1944. After a shaky start, it was championed by Chicago critics Ashton Stevens and Claudia Cassidy, whose enthusiasm helped build audiences so the producers could move the play to Broadway where it won the New York Drama Critics' Circle, New York Drama Critics' Circle Award in 1945. ''The Glass Menagerie'' was Williams' first successful play; he went on to become one of America's most highly regarded playwrights. Characters ; Amanda Wingfield: :A faded Southern belle who grew up in Blue Mountain ...
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Tennessee Williams
Thomas Lanier Williams III (March 26, 1911 – February 25, 1983), known by his pen name Tennessee Williams, was an American playwright and screenwriter. Along with contemporaries Eugene O'Neill and Arthur Miller, he is considered among the three foremost playwrights of 20th-century American drama. At age 33, after years of obscurity, Williams suddenly became famous with the success of ''The Glass Menagerie'' (1944) in New York City. He introduced "plastic theatre" in this play and it closely reflected his own unhappy family background. It was the first of a string of successes, including ''A Streetcar Named Desire'' (1947), ''Cat on a Hot Tin Roof'' (1955), ''Sweet Bird of Youth'' (1959), and ''The Night of the Iguana'' (1961). With his later work, Williams attempted a new style that did not appeal as widely to audiences. His drama ''A Streetcar Named Desire'' is often numbered on short lists of the finest American plays of the 20th century alongside Eugene O'Neill's '' Long Day ...
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Transgenesis
Gene delivery is the process of introducing foreign genetic material, such as DNA or RNA, into host cells. Gene delivery must reach the genome of the host cell to induce gene expression. Successful gene delivery requires the foreign gene delivery to remain stable within the host cell and can either integrate into the genome or replicate independently of it. This requires foreign DNA to be synthesized as part of a vector, which is designed to enter the desired host cell and deliver the transgene to that cell's genome. Vectors utilized as the method for gene delivery can be divided into two categories, recombinant viruses and synthetic vectors (viral and non-viral). In complex multicellular eukaryotes (more specifically Weissmanists), if the transgene is incorporated into the host's germline cells, the resulting host cell can pass the transgene to its progeny. If the transgene is incorporated into somatic cells, the transgene will stay with the somatic cell line, and thus its ho ...
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