Blepharitis
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Blepharitis
Blepharitis is one of the most common ocular conditions characterized by inflammation, scaling, reddening, and crusting of the eyelid. This condition may also cause swelling, burning, itching, or a grainy sensation when introducing foreign objects or substances to the eye. Although blepharitis by itself is not sight-threatening, it can lead to permanent alterations of the eyelid margin. The primary cause is bacteria and inflammation from congested meibomian oil glands at the base of each eyelash. Other conditions may give rise to blepharitis, whether they be infectious or noninfectious, including, but not limited to, bacterial infections or allergies. Different variations of blepharitis can be classified as seborrheic, staphylococcal, mixed, posterior or meibomitis, or parasitic. In a survey of US ophthalmologists and optometrists, 37% to 47% of patients seen by those surveyed had signs of blepharitis, which can affect all ages and ethnic groups. One single-center study of 90 pati ...
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Demodex
''Demodex'' is a genus of tiny mites that live in or near hair follicles of mammals. Around 65 species of ''Demodex'' are known. Two species live on humans: ''Demodex folliculorum'' and ''Demodex brevis'', both frequently referred to as eyelash mites, alternatively face mites or skin mites. Different species of animals host different species of ''Demodex''. ''Demodex canis'' lives on the domestic dog. The presence of ''Demodex'' species on mammals is common and usually does not cause any symptoms, although occasionally some skin diseases can be caused by the mites. ''Demodex'' is derived from Greek δημός ''dēmos'' "fat" and δήξ ''dēx'', "woodworm". Notable species ''D. folliculorum'' and ''D. brevis'' ''D. folliculorum'' and ''D. brevis'' are typically found on humans. ''D. folliculorum'' was first described in 1842 by Simon; ''D. brevis'' was identified as separate in 1963 by Akbulatova. ''D. folliculorum'' is found in hair follicles, while ''D. brevis'' lives in seb ...
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Hordeolum
A stye, also known as a hordeolum, is a bacterial infection of an oil gland in the eyelid. This results in a red tender bump at the edge of the eyelid. The outside or the inside of the eyelid can be affected. The cause of a stye is usually a bacterial infection by ''Staphylococcus aureus''. The internal ones are due to infection of the meibomian gland while the external ones are due to an infection of the gland of Zeis. A chalazion on the other hand is a blocked oil gland without infection. A chalazion is typically in the middle of the eyelid and not painful. Often a stye will go away without any specific treatment in a few days or weeks. Recommendations to speed improvement include warm compresses. Occasionally antibiotic eye ointment may be recommended. While these measures are often recommended, there is little evidence for use in internal styes. The frequency at which styes occur is unclear, though they may occur at any age. Signs and symptoms The first sign of a stye i ...
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Eyelid
An eyelid is a thin fold of skin that covers and protects an eye. The levator palpebrae superioris muscle retracts the eyelid, exposing the cornea to the outside, giving vision. This can be either voluntarily or involuntarily. The human eyelid features a row of eyelashes along the eyelid margin, which serve to heighten the protection of the eye from dust and foreign debris, as well as from perspiration. "Palpebral" (and "blepharal") means relating to the eyelids. Its key function is to regularly spread the tears and other secretions on the eye surface to keep it moist, since the cornea must be continuously moist. They keep the eyes from drying out when asleep. Moreover, the blink reflex protects the eye from foreign bodies. The appearance of the human upper eyelid often varies between different populations. The prevalence of an epicanthic fold covering the inner corner of the eye account for the majority of East Asian and Southeast Asian populations, and is also found i ...
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Meibomian Gland Dysfunction
Meibomian gland dysfunction (also known as MGD) is a chronic disease of the meibomian glands, which is commonly characterized by obstruction of the end of the duct that delivers the secretion produced by the glands (called meibum) to the eye surface, which prevents the glandular secretion to reach the ocular surface. The dysfunction could be that the amount of secretion produced may be abnormal (either too little or too much meibum produced). Dysfunction could also be related to the quality of the meibum produced. MGD may result in evaporative dry eye, blepharitis, chalazion, unsealed lid during sleep, and meibomian gland atrophy. MGD causes the glands to be obstructed by thick, cloudy-to-yellow, more opaque and viscous-like, oily and waxy secretions, a change from the glands' normal clear secretions.Peter Bex, Reza Dana, Linda Mcloon, Jerry Niederkorn (2011)''Ocular Periphery and Disorders''/ref> Besides leading to dry eyes, the obstructions can be degraded by bacterial lipases ...
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Demodicosis
Demodicosis , also called Demodex folliculitis in humans and demodectic mange () or red mange in animals, is caused by a sensitivity to and overpopulation of ''Demodex, Demodex spp.'' as the host's immune system is unable to keep the mites under control. ''Demodex'' is a genus of mite in the Family (biology), family Demodecidae. The mites are specific to their hosts, and each mammal species is host to one or two unique species of ''Demodex'' mites. Therefore, demodicosis cannot be transferred across species and has no Zoonosis, zoonotic potential. Signs and symptoms Humans Demodicosis in humans is usually caused by ''Demodex folliculorum'' and may have a rosacea-like appearance. Common symptoms include Hair loss#Infection, hair loss, itching, and inflammation. An association with pityriasis folliculorum has also been described. Demodicosis is most often seen in folliculitis (inflammation of the hair follicles of the skin). Depending on the location, it may result in small pus ...
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Photophobia
Photophobia is a medical symptom of abnormal intolerance to visual perception of light. As a medical symptom photophobia is not a morbid fear or phobia, but an experience of discomfort or pain to the eyes due to light exposure or by presence of actual physical sensitivity of the eyes, though the term is sometimes additionally applied to abnormal or irrational fear of light such as heliophobia. The term ''photophobia'' comes from the Greek language, Greek φῶς (''phōs''), meaning "light", and φόβος (''phóbos''), meaning "fear". Causes Patients may develop photophobia as a result of several different medical conditions, related to the human eye, eye, the nervous system, genetic, or other causes. Photophobia may manifest itself in an increased response to light starting at any step in the visual system, such as: *Too much light entering the eye. Too much light can enter the eye if it is damaged, such as with corneal abrasion and retinal damage, or if its pupil(s) is unabl ...
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Phthiriasis Palpebrarum
Pediculosis pubis (also known as "crabs" and "pubic lice") is an infestation by the pubic louse, ''Pthirus pubis'', a wingless insect which feeds on blood and lays its eggs (nits) on mainly pubic hair. Less commonly, hair near the anus, armpit, beard, eyebrows, moustache, and eyelashes may be involved. It is usually acquired during sex, but can be spread via bedding, clothing and towels, and is more common in crowded conditions where there is close contact between people. The main symptom is an intense itch in the groin, particularly at night. There may be some grey-blue discolouration at the feeding site, and eggs and lice may be visible. Scratch marks, crusting and scarring may be seen, and there may be signs of secondary bacterial infection. Diagnosis is by visualising the nits or live lice, either directly or with a magnifying glass. Investigations for other sexually transmitted infections (STIs) are usually performed. First line treatment usually contains permethrin a ...
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Demodex Folliculorum
''Demodex folliculorum'' is a microscopic mite that can only survive on the skin of humans. Most people have ''D.folliculorum'' on their skin. Usually, the mites do not cause any harm, so are considered an example of commensalism rather than parasitism. ''D.folliculorum''-caused disease, though, is known as demodicosis. Anatomy Due to being adapted to live inside hair follicles, ''D. folliculorum'' is thin and worm-like, with short legs. As an adult, ''D.folliculorum'' measures long. Adults have four pairs of legs; larvae and nymphs have only three pairs. ''D.folliculorum'' has a rudimentary gut and anus. Reproduction and life cycle The entire life cycle of ''D.folliculorum'' takes 14–16 days. Adult mites copulate at the top of the hair follicle, near the skin surface. Eggs are deposited in the sebaceous gland inside the hair follicle. The heart-shaped egg is long, and hatches into a six-legged larva. Seven days are needed for the larva to develop into a mature adult, with t ...
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Eyelash
An eyelash (also called lash) (Latin: ''Cilia'') is one of the hairs that grows at the edge of the eyelids. It grows in one layer on the edge of the upper and lower eyelids. Eyelashes protect the eye from debris, dust, and small particles and perform some of the same functions as whiskers do on a cat or a mouse in the sense that they are sensitive to being touched, thus providing a warning that an object (such as an insect) is near the eye (which then closes reflexively). The Ancient Greek word for eyelash is βλέφαρον (transliterated as blepharon), which is seen as a root in biological terms like ''Blephara''. Structure Development The eyelashes of the human embryo develop from the ectoderm between the 22nd and 26th week of pregnancy. Natural eyelashes do not grow beyond a certain length, and fall off by themselves without any need for trimming. Eyelashes take about seven to eight weeks to grow back if pulled out, but constant pulling may lead to permanent damage. Their ...
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Parasitic Infection
A parasitic disease, also known as parasitosis, is an infectious disease caused by parasites. Parasites are organisms which derive sustenance from its host while causing it harm. The study of parasites and parasitic diseases is known as parasitology. Medical parasitology is concerned with three major groups of parasites: parasitic protozoa, helminths, and parasitic arthropods. Parasitic diseases are thus considered those diseases that are caused by pathogens belonging taxonomically to either the animal kingdom, or the protozoan kingdom. Terminology Although organisms such as bacteria function as parasites, the usage of the term "parasitic disease" is usually more restricted. The three main types of organisms causing these conditions are protozoa (causing protozoan infection), helminths (helminthiasis), and ectoparasites. Protozoa and helminths are usually endoparasites (usually living inside the body of the host), while ectoparasites usually live on the surface of the host. Protozoa ...
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Ophthalmology
Ophthalmology ( ) is a surgical subspecialty within medicine that deals with the diagnosis and treatment of eye disorders. An ophthalmologist is a physician who undergoes subspecialty training in medical and surgical eye care. Following a medical degree, a doctor specialising in ophthalmology must pursue additional postgraduate residency training specific to that field. This may include a one-year integrated internship that involves more general medical training in other fields such as internal medicine or general surgery. Following residency, additional specialty training (or fellowship) may be sought in a particular aspect of eye pathology. Ophthalmologists prescribe medications to treat eye diseases, implement laser therapy, and perform surgery when needed. Ophthalmologists provide both primary and specialty eye care - medical and surgical. Most ophthalmologists participate in academic research on eye diseases at some point in their training and many include research as part ...
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Dermis
The dermis or corium is a layer of skin between the epidermis (with which it makes up the cutis) and subcutaneous tissues, that primarily consists of dense irregular connective tissue and cushions the body from stress and strain. It is divided into two layers, the superficial area adjacent to the epidermis called the papillary region and a deep thicker area known as the reticular dermis.James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology'' (10th ed.). Saunders. Pages 1, 11–12. . The dermis is tightly connected to the epidermis through a basement membrane. Structural components of the dermis are collagen, elastic fibers, and extrafibrillar matrix.Marks, James G; Miller, Jeffery (2006). ''Lookingbill and Marks' Principles of Dermatology'' (4th ed.). Elsevier Inc. Page 8–9. . It also contains mechanoreceptors that provide the sense of touch and thermoreceptors that provide the sense of heat. In addition, hair follicles, ...
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