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Young Blood Transfusion
Young blood transfusion refers to transfusing blood specifically from a young person into an older one with the intention of creating a health benefit. The scientific community currently views the practice as essentially pseudoscientific, with comparisons to snake oil. There are also concerns of harm. The U.S. Food and Drug Administration, in 2019, cautioned "consumers against receiving young donor plasma infusions" stating that they are an "unproven treatment". Research Experiments beginning in the 1950s in the Cornell University lab of Clive McCay on pairs of old and young rodents placed into parabiosis provided some evidence, albeit limited and "largely anecdotal", that the circulation of blood from young mice increased both the longevity and the tissue function of old mice. After decades in which relatively little work on parabiosis in aging was done, the work was revived by researchers at Stanford University and the University of California at Berkeley. Parabiosis experim ...
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Blood Transfusion
Blood transfusion is the process of transferring blood products into a person's circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood cells, white blood cells, plasma, clotting factors and platelets. Red blood cells (RBC) contain hemoglobin, and supply the cells of the body with oxygen. White blood cells are not commonly used during transfusion, but they are part of the immune system, and also fight infections. Plasma is the "yellowish" liquid part of blood, which acts as a buffer, and contains proteins and important substances needed for the body's overall health. Platelets are involved in blood clotting, preventing the body from bleeding. Before these components were known, doctors believed that blood was homogeneous. Because of this scientific misunderstanding, many patients die ...
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Clinical Trial
Clinical trials are prospective biomedical or behavioral research studies on human subject research, human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, pharmaceutical drug, drugs, medical nutrition therapy, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received institutional review board, health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small Pilot experiment, pi ...
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Alternative Medicine
Alternative medicine is any practice that aims to achieve the healing effects of medicine despite lacking biological plausibility, testability, repeatability, or evidence from clinical trials. Complementary medicine (CM), complementary and alternative medicine (CAM), integrated medicine or integrative medicine (IM), and holistic medicine attempt to combine alternative practices with those of mainstream medicine. Alternative therapies share in common that they reside outside of medical science and instead rely on pseudoscience. Traditional practices become "alternative" when used outside their original settings and without proper scientific explanation and evidence. Frequently used derogatory terms for relevant practices are ''new age'' or ''pseudo-'' medicine, with little distinction from quackery. Some alternative practices are based on theories that contradict the established science of how the human body works; others resort to the supernatural or superstitious to expl ...
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Life Extension Foundation
The Biomedical Research & Longevity Society, formerly the Life Extension Foundation (LEF), is a company founded in 1980 to extend the healthy human lifespan by discovering methods to control aging and eradicate disease. Along with the Life Extension Buyer's Club, which sells vitamins and supplements, the Life Extension Foundation (LEF) was headquartered in Fort Lauderdale, Florida. It also has a call center location in Las Vegas, Nevada. The company changed its name in 2018 to Biomedical Research & Longevity Society. Activities Along with the Life Extension Buyer's Club, the Life Extension Foundation (LEF) was headquartered in Fort Lauderdale, Florida. The Life Extension Foundation (LEF) was primarily funded by the sale of nutritional supplements to members of an affiliated entity, the Life Extension Buyer's Club. The Life Extension Buyer's Club was incorporated in Nevada, and has a separate EIN employer number than the Life Extension Foundation. Its name was changed to the Biomed ...
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Hippocrates Health Institute
The Hippocrates Health Institute (HHI) is a nonprofit organization in West Palm Beach, Florida, USA, originally co-founded in 1956 in Stoneham, Massachusetts, by Lithuanian-born Viktoras Kulvinskas and Ann Wigmore. The Hippocrates Health Institute is regarded as controversial for supposedly treating cancer with unproven natural methods that are implausible despite claims otherwise. In February and March 2015, cease-and-desist orders were issued against co-directors Brian and Anna-Maria Clement, both of whom represented themselves as doctors, requiring them to immediately cease the unlicensed practice of medicine. The Florida Department of Health formally informed Hippocrates Health Institute that it has subsequently withdrawn and dismissed the cease-and-desist orders due to lack of sufficient evidence. Brian Clement and his institute have been directly criticized for promoting a number of ineffective treatments, including ones claimed to "reverse" cancer and multiple sclerosis. ...
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Clinical Control Group
In the design of experiments, hypotheses are applied to experime