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Trichosanthes Kirilowii
''Trichosanthes kirilowii'' is a flowering plant in the family Cucurbitaceae found particularly in Henan, Shandong, Hebei, Shanxi, and Shaanxi. It is one of the 50 fundamental herbs used in traditional Chinese medicine, where it shares the name ''guālóu'' () with the related ''T. rosthornii''. It is known as "Chinese cucumber" and "Chinese snake gourd" in English. Traditional uses The tuber of this plant is known in Mandarin as ''tiān huā fěn'' (). In traditional Chinese medicine it is said to drain heat and generate fluids, clear and drain lung heat, transform phlegm, and moisten lung dryness, and resolve toxicity and expel pus. The fruit of the plant, also referred to in Mandarin as ''guālóu'' (), is said to clear heat and transform phlegm-heat, unbind the chest, reduces abscesses and dissipate nodules. Both forms should be considered safe only for use with professional guidance by someone trained in their use, though this may be an unnecessary extrapolation from the to ...
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Maxim
Maxim or Maksim may refer to: Entertainment * ''Maxim'' (magazine), an international men's magazine ** ''Maxim'' (Australia), the Australian edition ** ''Maxim'' (India), the Indian edition *Maxim Radio, ''Maxim'' magazine's radio channel on Sirius Satellite Radio *''Maxim'', a fictional ship in the manga and anime series ''One Piece'' *Maxim, the hero of the video game '' Lufia II: Rise of the Sinistrals'' and its remake, '' Lufia: Curse of the Sinistrals'' Literature and language *A species of adage, aphorism, or saying that expresses a general moral rule, especially a philosophical maxim * ''Maxims'' (Old English poems), examples of gnomic poetry *'' Maximes'' (1665–78) of François de La Rochefoucauld (1613–80) Organizations *Mary Maxim, craft and needlework mail-order company in Canada *Maxim Brewery, brewing company in England *Maxim's Catering, chain of caterers, restaurants, and fast food shops in Hong Kong *Maxim Healthcare Services, medical staffing and home hea ...
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Toxicity
Toxicity is the degree to which a chemical substance or a particular mixture of substances can damage an organism. Toxicity can refer to the effect on a whole organism, such as an animal, bacterium, or plant, as well as the effect on a substructure of the organism, such as a cell ( cytotoxicity) or an organ such as the liver (hepatotoxicity). By extension, the word may be metaphorically used to describe toxic effects on larger and more complex groups, such as the family unit or society at large. Sometimes the word is more or less synonymous with poisoning in everyday usage. A central concept of toxicology is that the effects of a toxicant are dose-dependent; even water can lead to water intoxication when taken in too high a dose, whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect. Toxicity is species-specific, making cross-species analysis problematic. Newer paradigms and metrics are evolving to bypas ...
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Trichosanthes
''Trichosanthes'' is a genus of tropical and subtropical vines. They belong to the cucumber family (Cucurbitaceae), and are closely related to '' Gymnopetalum''. ''Hodgsonia'', formerly included here, is usually considered a well-distinct genus nowadays. The shoots, tendrils, and leaves of some or possibly all species may be eaten as greens, and at least two species ( serpent gourd, ''T. cucumerina'', and pointed gourd, ''T. dioica'') are grown commercially for their fleshy fruits used as vegetables, most popular in South Asia and Southeast Asia. At least two species ('' T. kirilowii'' and '' T. rosthornii'') are grown for use in traditional Chinese medicine, where they are called the name ''gualou'' (). ''Trichosanthes'' is also known as a medicinal as well as poisonous plant in India. The herb has shown an ability to reduce chest congestion by breaking down phlegm and aiding in its removal from the lungs. Selected species * ''Trichosanthes baviensis'' Gagnepain * '' Trichos ...
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United States National Agricultural Library
The United States National Agricultural Library (NAL) is one of the world's largest agricultural research libraries, and serves as a national library of the United States and as the library of the United States Department of Agriculture. Located in Beltsville, Maryland, it is one of five national libraries of the United States (along with the Library of Congress, the National Library of Medicine, the National Transportation Library, and the National Library of Education). It is also the coordinator for the Agriculture Network Information Center (AgNIC), a national network of state land-grant institutions and coordinator for the U.S. Department of Agriculture (USDA) field libraries. NAL was established on May 15, 1862, by the signing of the Organic Act by Abraham Lincoln. It served as a departmental library until 1962, when the Secretary of Agriculture officially designated it as the National Agricultural Library. The first librarian, appointed in 1867, was Aaron B. Grosh, one ...
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Ricin
Ricin ( ) is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, ''Ricinus communis''. The median lethal dose (LD50) of ricin for mice is around 22 micrograms per kilogram of body weight via intraperitoneal injection. Oral exposure to ricin is far less toxic. An estimated lethal oral dose in humans is approximately 1 milligram per kilogram of body weight. Ricin was first described by Peter Hermann Stillmark, the founder of lectinology. Biochemistry Ricin is classified as a type 2 ribosome-inactivating protein (RIP). Whereas type 1 RIPs are composed of a single protein chain that possesses catalytic activity, type 2 RIPs, also known as holotoxins, are composed of two different protein chains that form a heterodimeric complex. Type 2 RIPs consist of an A chain that is functionally equivalent to a type 1 RIP, covalently connected by a single disulfide bond to a B chain that is catalytically inactive, but serves to m ...
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In Vitro
''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology and its subdisciplines are traditionally done in labware such as test tubes, flasks, Petri dishes, and microtiter plates. Studies conducted using components of an organism that have been isolated from their usual biological surroundings permit a more detailed or more convenient analysis than can be done with whole organisms; however, results obtained from ''in vitro'' experiments may not fully or accurately predict the effects on a whole organism. In contrast to ''in vitro'' experiments, ''in vivo'' studies are those conducted in living organisms, including humans, and whole plants. Definition ''In vitro'' ( la, in glass; often not italicized in English usage) studies are conducted using components of an organism that have been isolated fro ...
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AIDS Virus
The human immunodeficiency viruses (HIV) are two species of '' Lentivirus'' (a subgroup of retrovirus) that infect humans. Over time, they cause acquired immunodeficiency syndrome (AIDS), a condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment, average survival time after infection with HIV is estimated to be 9 to 11 years, depending on the HIV subtype. In most cases, HIV is a sexually transmitted infection and occurs by contact with or transfer of blood, pre-ejaculate, semen, and vaginal fluids. Non-sexual transmission can occur from an infected mother to her infant during pregnancy, during childbirth by exposure to her blood or vaginal fluid, and through breast milk. Within these bodily fluids, HIV is present as both free virus particles and virus within infected immune cells. Research has shown (for both same-sex and opposite-sex couples) that HIV is untransmittable throug ...
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Trichosanthin
Trichosanthin is a ribosome-inactivating protein. It is derived from ''Trichosanthes kirilowii''. It is also an abortifacient An abortifacient ("that which will cause a miscarriage" from Latin: ''abortus'' "miscarriage" and '' faciens'' "making") is a substance that induces abortion. This is a nonspecific term which may refer to any number of substances or medications, .... References External links * Proteins Ribosome-inactivating proteins {{pharmacology-stub ...
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Traditional Chinese Medicine
Traditional Chinese medicine (TCM) is an alternative medical practice drawn from traditional medicine in China. It has been described as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action. Medicine in traditional China encompassed a range of sometimes competing health and healing practices, folk beliefs, literati theory and Confucian philosophy, herbal remedies, food, diet, exercise, medical specializations, and schools of thought. In the early twentieth century, Chinese cultural and political modernizers worked to eliminate traditional practices as backward and unscientific. Traditional practitioners then selected elements of philosophy and practice and organized them into what they called "Chinese medicine" (''Zhongyi''). In the 1950s, the Chinese government sponsored the integration of Chinese and Western medicine, and in the Great Proletarian Cultural Revolution of the 1960s, promoted Chinese medicine as inexpensive a ...
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Flowering Plant
Flowering plants are plants that bear flowers and fruits, and form the clade Angiospermae (), commonly called angiosperms. The term "angiosperm" is derived from the Greek words ('container, vessel') and ('seed'), and refers to those plants that produce their seeds enclosed within a fruit. They are by far the most diverse group of land plants with 64 orders, 416 families, approximately 13,000 known genera and 300,000 known species. Angiosperms were formerly called Magnoliophyta (). Like gymnosperms, angiosperms are seed-producing plants. They are distinguished from gymnosperms by characteristics including flowers, endosperm within their seeds, and the production of fruits that contain the seeds. The ancestors of flowering plants diverged from the common ancestor of all living gymnosperms before the end of the Carboniferous, over 300 million years ago. The closest fossil relatives of flowering plants are uncertain and contentious. The earliest angiosperm fossils ar ...
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Chinese Herbology
Chinese herbology () is the theory of traditional Chinese herbal therapy, which accounts for the majority of treatments in traditional Chinese medicine (TCM). A ''Nature'' editorial described TCM as "fraught with pseudoscience", and said that the most obvious reason why it has not delivered many cures is that the majority of its treatments have no logical mechanism of action. The term herbology is misleading in the sense that, while plant elements are by far the most commonly used substances, animal, human, and mineral products are also utilized, among which some are poisonous. In the ''Huangdi Neijing'' they are referred to as () which means toxin, poison, or medicine. Paul U. Unschuld points out that this is similar etymology to the Greek '' pharmakon'' and so he uses the term "pharmaceutic". Thus, the term "medicinal" (instead of herb) is usually preferred as a translation for (). Research into the effectiveness of traditional Chinese herbal therapy is of poor quality and ...
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Shaanxi
Shaanxi (alternatively Shensi, see #Name, § Name) is a landlocked Provinces of China, province of China. Officially part of Northwest China, it borders the province-level divisions of Shanxi (NE, E), Henan (E), Hubei (SE), Chongqing (S), Sichuan (SW), Gansu (W), Ningxia (NW) and Inner Mongolia (N). Shaanxi covers an area of over with about 37 million people, the 16th highest in China. Xi'an – which includes the sites of the former Capitals of China, Chinese capitals Fenghao and Chang'an – is the Xi'an, provincial capital as well as the largest city in Northwest China and also one of the oldest cities in China and the oldest of the Historical capitals of China, Four Great Ancient Capitals, being the capital for the Western Zhou, Western Han, Sima Jin, Jin, Sui dynasty, Sui and Tang dynasty, Tang List of Chinese dynasties, dynasties. Xianyang, which served as the Qin dynasty capital, is just north across Wei River. The other Prefectures of China, prefecture-level pr ...
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