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Toxascaris Leonina
''Toxascaris leonina'' is a common parasitic roundworm found in dogs, cats, foxes, and related host species. ''T. leonina'' is an ascarid nematode, a worldwide distributed helminth parasite which is in a division of eukaryotic parasites that, unlike external parasites such as lice and fleas, live inside their host. The definitive hosts of ''T. leonina'' include canids (dogs, foxes, etc.) and felines (cats), while the intermediate hosts are usually rodents, such as mice or rats. Infection occurs in the definitive host when the animal eats an infected rodent. While ''T. leonina'' can occur in either dogs or cats, it is far more frequent in cats. A coprolite containing ''T. leonina'' eggs was excavated in Argentina's Catamarca Province and dated to 17002–16573 years old. This finding indicates that ''T. leonina'' has existed in South America since at least the Late Pleistocene. Life cycle The life cycle of ''T. leonina'' is fairly simple. Eggs are ingested and hatch in t ...
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Animal
Animals are multicellular, eukaryotic organisms in the Kingdom (biology), biological kingdom Animalia. With few exceptions, animals Heterotroph, consume organic material, Cellular respiration#Aerobic respiration, breathe oxygen, are Motility, able to move, can Sexual reproduction, reproduce sexually, and go through an ontogenetic stage in which their body consists of a hollow sphere of Cell (biology), cells, the blastula, during Embryogenesis, embryonic development. Over 1.5 million Extant taxon, living animal species have been Species description, described—of which around 1 million are Insecta, insects—but it has been estimated there are over 7 million animal species in total. Animals range in length from to . They have Ecology, complex interactions with each other and their environments, forming intricate food webs. The scientific study of animals is known as zoology. Most living animal species are in Bilateria, a clade whose members have a Symmetry in biology#Bilate ...
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Mice
A mouse ( : mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a high breeding rate. The best known mouse species is the common house mouse (''Mus musculus''). Mice are also popular as pets. In some places, certain kinds of field mice are locally common. They are known to invade homes for food and shelter. Mice are typically distinguished from rats by their size. Generally, when a muroid rodent is discovered, its common name includes the term ''mouse'' if it is smaller, or ''rat'' if it is larger. The common terms ''rat'' and ''mouse'' are not taxonomically specific. Typical mice are classified in the genus ''Mus'', but the term ''mouse'' is not confined to members of ''Mus'' and can also apply to species from other genera such as the deer mouse, ''Peromyscus''. Domestic mice sold as pets often differ substantially in size from the common house mouse. This is attributable to breeding an ...
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Milbemycin Oxime
Milbemycin oxime, sold under the brand name Interceptor among others, is a veterinary medication from the group of milbemycins, used as a broad spectrum antiparasitic. It is active against worms (anthelmintic) and mites (miticide). Mechanism of action Milbemycins are products of fermentation (biochemistry), fermentation by ''Streptomyces'' species. They have a similar mechanism of action, but a longer half-life than the avermectins. Milbemycin oxime is produced by ''Streptomyces hygroscopicus aureolacrimosus''. It opens glutamate sensitive chloride channels in neurons and myocytes of invertebrates, leading to hyperpolarization (biology), hyperpolarisation of these cells and blocking of signal transfer. Uses Milbemycin oxime is active against a broad spectrum of nematodes. Its miticide spectrum includes ''Sarcoptes scabiei, Sarcoptes'' and ''Demodex''. The drug is FDA-approved for prevention of heartworm in dogs and cats, although it is less potent against heartworms than ivermecti ...
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Pyrantel
Pyrantel is a medication used to treat a number of parasitic worm infections. This includes ascariasis, hookworm infections, enterobiasis (pinworm infection), trichostrongyliasis, and trichinellosis. It is taken by mouth. Side effects include nausea, headache, dizziness, trouble sleeping, and rash. A lower dose should be used in people with liver disease. While it does not appear to be harmful during pregnancy, it has not been studied for this use. It is unclear if it is safe for use during breastfeeding. It is in the antihelmintic family of medications. It works by paralyzing worms. Pyrantel was initially described in 1965. It is on the WHO Model List of Essential Medicines, World Health Organization's List of Essential Medicines. Pyrantel is available as a generic medication. It may also be used to treat worms in a number of other animals. Pregnancy and breastfeeding Pyrantel pamoate is considered a pregnancy category C drug for use during pregnancy for humans, but is in ...
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Fenbendazole
Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus '' Taenia'' (but not effective against '' Dipylidium caninum'', a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats, rabbits, most reptiles, freshwater shrimp tanks as planaria and hydra treatments, as well as seals. Drug interactions Drug interactions may occur if salicylanilides such as dibromsalan and niclosamide are co-administered. Abortions in cattle and death in sheep have been reported after using these medications together. Abortions in domestic ruminants have been associated with concurrent use of anti-trematode therapeutic agents. Toxicity Fenbendazole is poorly absorbed from the gastrointestinal tract in most species. The in laboratory animals exceeds 10 g/kg when admi ...
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Fecal Flotation
Feces ( or faeces), known colloquially and in slang as poo and poop, are the solid or semi-solid remains of food that was not digested in the small intestine, and has been broken down by bacteria in the large intestine. Feces contain a relatively small amount of metabolic waste products such as bacterially altered bilirubin, and dead epithelial cells from the lining of the gut. Feces are discharged through the anus or cloaca during defecation. Feces can be used as fertilizer or soil conditioner in agriculture. They can also be burned as fuel or dried and used for construction. Some medicinal uses have been found. In the case of human feces, fecal transplants or fecal bacteriotherapy are in use. Urine and feces together are called excreta. Skatole is the principal compound responsible for the unpleasant smell of feces. Characteristics The distinctive odor of feces is due to skatole, and thiols ( sulfur-containing compounds), as well as amines and carboxylic acid ...
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Toxocariasis
Toxocariasis is an illness of humans caused by the dog roundworm ('' Toxocara canis'') and, less frequently, the cat roundworm (''Toxocara cati'').https://academic.oup.com/ajcp/article/142/suppl_1/A104/1771175 Eosinophilic Pseudoleukemia Due to Toxocariasis in a 3-year-old Patient: Report of A Rare Case These are the most common intestinal roundworms of dogs, coyotes, wolves and foxes and domestic cats, respectively. Humans are among the many "accidental" or paratenic hosts of these roundworms. While this zoonotic infection is usually asymptomatic, it may cause severe disease. There are three distinct syndromes of toxocariasis: '' covert toxocariasis'' is a relatively mild illness very similar to Löffler's syndrome. It is characterized by fever, eosinophilia, urticaria, enlarged lymph nodes, cough, bronchospasm, wheezing, abdominal pain, headaches, and/or hepatosplenomegaly. '' Visceral larva migrans'' (VLM) is a more severe form of the disease; signs and symptoms depend on the ...
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Toxocara Cati
''Toxocara cati'', also known as the feline roundworm, is a parasite of cats and other felids. It is one of the most common nematodes of cats, infecting both wild and domestic felids worldwide. Adult worms are localised in the gut of the host. In adult cats, the infection – which is called toxocariasis – is usually asymptomatic. However, massive infection in juvenile cats can be fatal. Feline roundworms are brownish-yellow to cream-colored to pink and may be up to 10 cm in length. Adults have short, wide cervical alae giving their anterior ends the distinct appearance of an arrow (hence their name, ''toxo'', meaning arrow, and ''cara,'' meaning head). Eggs are pitted ovals with a width of 65 μm and a length of about 75 μm making them invisible to the human eye. The larvae are so small that they are easily transmitted from an adult female to her nursing kittens through her milk. Transmission Wild felids can become infected from a variety of sources; the prim ...
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Toxocara Canis
''Toxocara canis'' (also known as dog roundworm) is a worldwide-distributed helminth parasite of dogs and other canids. The name is derived from the Greek word "," meaning bow or quiver, and the Latin word "caro," meaning flesh.Bassert , J., & Thomas, J. (2014). McCurnin's Clinical Textbook for Veterinary Technicians. (8th ed.). St. Louis , MO: Elsevier They live in the small intestine of the definitive host. In adult dogs, the infection is usually asymptomatic but may be characterized by diarrhea. By contrast, massive infection with ''Toxocara canis'' can be fatal in puppies, causing diarrhea, vomiting, an enlarged abdomen, flatulence, and poor growth rate. As paratenic hosts, a number of vertebrates, including humans, and some invertebrates can become infected. Humans are infected, like other paratenic hosts, by ingestion of embryonated ''T. canis'' eggs. The disease (toxocariasis) caused by migrating ''T. canis'' larvae results in two syndromes: visceral larva migrans and o ...
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Toxocara
The Toxocaridae are a zoonotic family of parasitic nematodes that infect canids and felids and which cause toxocariasis in humans ( visceral larva migrans and ocular larva migrans). The worms are unable to reproduce in humans. Notable species include: *'' Toxocara canis'', which infects dogs. *''Toxocara cati'', which infects cats and lacks intermediate hosts. *''Toxascaris leonina'', which infects mostly cats, but also dogs. *''Toxocara malayasiensis'', which infects cats. *''Toxocara vitulorum'', which infects buffalo and cattle. Infection Infection by ''T. canis'' or ''T. cati'' can cause various clinical manifestations. One of these is visceral larva migrans, wherein the larvae are unable to develop in humans as they do in cats and dogs, their natural hosts. Arrested development leaves the larvae to wander aimlessly in the body, causing inflammation, most commonly in the liver and lungs. Eggs are introduced into the body through ingestion. This can occur when eggs are de ...
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Egg (biology)
An egg is an organic vessel grown by an animal to carry a possibly fertilized egg cell (a zygote) and to incubate from it an embryo within the egg until the embryo has become an animal fetus that can survive on its own, at which point the animal hatches. Most arthropods such as insects, vertebrates (excluding live-bearing mammals), and mollusks lay eggs, although some, such as scorpions, do not. Reptile eggs, bird eggs, and monotreme eggs are laid out of water and are surrounded by a protective shell, either flexible or inflexible. Eggs laid on land or in nests are usually kept within a warm and favorable temperature range while the embryo grows. When the embryo is adequately developed it hatches, i.e., breaks out of the egg's shell. Some embryos have a temporary egg tooth they use to crack, pip, or break the eggshell or covering. The largest recorded egg is from a whale shark and was in size. Whale shark eggs typically hatch within the mother. At and up to , the ost ...
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Late Pleistocene
The Late Pleistocene is an unofficial age in the international geologic timescale in chronostratigraphy, also known as Upper Pleistocene from a stratigraphic perspective. It is intended to be the fourth division of the Pleistocene Epoch within the ongoing Quaternary Period. It is currently defined as the time between c. 129,000 and c. 11,700 years ago. The Late Pleistocene equates to the proposed Tarantian Age of the geologic time scale, preceded by the officially ratified Chibanian (formerly known as Middle Pleistocene) and succeeded by the officially ratified Greenlandian. The estimated beginning of the Tarantian is the start of the Eemian interglacial period ( Marine Isotope Stage 5). It is held to end with the termination of the Younger Dryas, some 11,700 years ago when the Holocene Epoch began. The term Upper Pleistocene is currently in use as a provisional or "quasi-formal" designation by the International Union of Geological Sciences (IUGS). Although the three olde ...
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