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Sverdlovsk Anthrax Leak
On 2 April 1979, spores of ''Bacillus anthracis'' (the causative agent of anthrax) were accidentally released from a Soviet Armed Forces research facility in the city of Sverdlovsk in the Soviet Union. The ensuing outbreak of the disease resulted in the deaths of at least 68 people, although the exact number of victims remains unknown. The cause of the outbreak was denied for years by the Soviet authorities, which blamed the deaths on consumption of tainted meat from the area, and subcutaneous exposure due to butchers handling the tainted meat. The accident was the first major indication in the Western world that the Soviet Union had embarked upon an offensive programme aimed at the development and large-scale production of biological weapons. Background Sverdlovsk had been a major production center of the Soviet military-industrial complex since World War II. By the 1970s, 87 percent of the city's industrial production was military; only 13 percent for public consumption. ...
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Bacillus Anthracis
''Bacillus anthracis'' is a gram-positive and rod-shaped bacterium that causes anthrax, a deadly disease to livestock and, occasionally, to humans. It is the only permanent (obligate) pathogen within the genus ''Bacillus''. Its infection is a type of zoonosis, as it is transmitted from animals to humans. It was discovered by a German physician Robert Koch in 1876, and became the first bacterium to be experimentally shown as a pathogen. The discovery was also the first scientific evidence for the germ theory of diseases. ''B. anthracis'' measures about 3 to 5 μm long and 1 to 1.2 μm wide. The reference genome consists of a 5,227,419 bp circular chromosome and two extrachromosomal DNA plasmids, pXO1 and pXO2, of 181,677 and 94,830 bp respectively, which are responsible for the pathogenicity. It forms a protective layer called endospore by which it can remain inactive for many years and suddenly becomes infective under suitable environmental conditions. Because of the resilience ...
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Closed City
A closed city or town is a settlement where travel or residency restrictions are applied. Historically, the construction of closed cities became increasingly common after the beginning of the Cold War, particularly in the Soviet Union. Since the dissolution of the Soviet Union in 1991, they remain widespread in Russia and some of the other post-Soviet countries. In modern Russia the closed cities are designated as "closed administrative–territorial formations" (ZATO; , ). Structure and operations Closed cities are sometimes represented only on Classified information, classified maps that are not available to the general public. Sometimes, closed cities are indicated obliquely as a nearby insignificant village, with the name of the stop serving the closed city made equivocal or misleading. For mail delivery, a closed city is usually named as the nearest large city and a special postcode, for example, Arzamas‑16, Chelyabinsk‑65. The actual settlement can be rather dista ...
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Harvard University
Harvard University is a Private university, private Ivy League research university in Cambridge, Massachusetts, United States. Founded in 1636 and named for its first benefactor, the History of the Puritans in North America, Puritan clergyman John Harvard (clergyman), John Harvard, it is the oldest institution of higher learning in the United States. Its influence, wealth, and rankings have made it one of the most prestigious universities in the world. Harvard was founded and authorized by the Massachusetts General Court, the governing legislature of Colonial history of the United States, colonial-era Massachusetts Bay Colony. While never formally affiliated with any Religious denomination, denomination, Harvard trained Congregationalism in the United States, Congregational clergy until its curriculum and student body were gradually secularized in the 18th century. By the 19th century, Harvard emerged as the most prominent academic and cultural institution among the Boston B ...
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Matthew Meselson
Matthew Stanley Meselson (born May 24, 1930) is a geneticist and molecular biologist currently at Harvard University, known for his demonstration, with Franklin Stahl, of semi-conservative DNA replication. After completing his Ph.D. under Linus Pauling at the California Institute of Technology, Meselson became a Professor at Harvard University in 1960, where he has remained today as Professor of the Natural Sciences. In the famous Meselson–Stahl experiment of 1958 he and Frank Stahl demonstrated through nitrogen isotope labeling that DNA is replicated semi-conservatively. In addition, Meselson, François Jacob, and Sydney Brenner discovered the existence of messenger RNA in 1961. Meselson has investigated DNA repair in cells and how cells recognize and destroy foreign DNA, and, with Werner Arber, was responsible for the discovery of restriction enzymes. Since 1963 he has been interested in chemical and biological defense and arms control, has served as a consultant on this ...
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Tbilisi
Tbilisi ( ; ka, თბილისი, ), in some languages still known by its pre-1936 name Tiflis ( ), ( ka, ტფილისი, tr ) is the Capital city, capital and List of cities and towns in Georgia (country), largest city of Georgia (country), Georgia, located on the banks of the Kura (Caspian Sea), Kura River. With around 1.2 million inhabitants, it contains almost one third of the country's population. Tbilisi was founded in the fifth century Anno Domini, AD by Vakhtang I of Iberia and has since served as the capital of various Georgian kingdoms and republics. Between 1801 and 1917, then part of the Russian Empire, it was the seat of the Caucasus Viceroyalty (1801–1917), Caucasus Viceroyalty, governing both the North Caucasus, northern and the South Caucasus, southern sides of the Caucasus. Because of its location at the crossroads between Europe and Asia, and its proximity to the lucrative Silk Road, throughout history, Tbilisi has been a point of contention ...
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Polyclinics
A polyclinic (where ''poly'' means "many"; not to be confused with the homonym policlinic, where ''poli'' means "city" and which is sometimes used for a hospital's outpatient department) is a clinic or health care facility that provides both general and specialist examinations and treatments for a wide variety of diseases and injuries to outpatients and is usually independent of a hospital. When a polyclinic is so large that it is in fact a hospital, it is also called a general hospital. The term was rare in English until recently and is still very rare in North America, examples include the polyclinics in England (large health care centres able to provide a wider range of services than a standard doctor's (GP) office) and The Polyclinic in Seattle, Washington, US. Most other languages use a cognate of the even rarer English term " policlinic" (spelled similarly to and pronounced the same as the English term "polyclinic") for outpatient departments (outpatient clinics) of (pu ...
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Tetracycline
Tetracycline, sold under various brand names, is an antibiotic in the tetracyclines family of medications, used to treat a number of infections, including acne, cholera, brucellosis, plague, malaria, and syphilis. It is available in oral and topical formulations. Common side effects include vomiting, diarrhea, rash, and loss of appetite. Other side effects include poor tooth development if used by children less than eight years of age, kidney problems, and sunburning easily. Use during pregnancy may harm the baby. It works by inhibiting protein synthesis in bacteria. Tetracycline was patented in 1953 and was approved for prescription use in 1954. It is on the World Health Organization's List of Essential Medicines. Tetracycline is available as a generic medication. Tetracycline was originally made from bacteria of the genus ''Streptomyces''. Medical uses Spectrum of activity Tetracyclines have a broad spectrum of antibiotic action. Originally, they possessed some lev ...
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Workforce
In macroeconomics, the workforce or labour force is the sum of people either working (i.e., the employed) or looking for work (i.e., the unemployed): \text = \text + \text Those neither working in the marketplace nor looking for work are out of the labour force. The sum of the labour force and out of the labour force results in the noninstitutional civilian population, that is, the number of people who (1) work (i.e., the employed), (2) can work but don't, although they are looking for a job (i.e., the unemployed), or (3) can work but don't, and are not looking for a job (i.e., out of the labour force). Stated otherwise, the noninstitutional civilian population is the total population minus people who cannot or choose not to work (children, retirees, soldiers, and incarcerated people). The noninstitutional civilian population is the number of people potentially available for civilian employment. \begin \text &= \text + \text \\ & ...
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Botulinum Toxin
Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium ''Clostridium botulinum'' and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes. Botulinum toxin is an acetylcholine release inhibitor and a neuromuscular blocking agent. The seven main types of botulinum toxin are named types A to G (A, B, C1, C2, D, E, F and G). New types are occasionally found. Types A and B are capable of causing disease in humans, and are also used commercially and medically. Types C–G are less common; types E and F can cause disease in humans, while the other types cause disease in other animals. Botulinum toxins are among the most potent toxins known to science. Intoxication can occur naturally as a result of eithe ...
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The Chilling True Story Of The Largest Covert Biological Weapons Program In The World – Told From Inside By The Man Who Ran It
''The'' is a grammatical article in English, denoting nouns that are already or about to be mentioned, under discussion, implied or otherwise presumed familiar to listeners, readers, or speakers. It is the definite article in English. ''The'' is the most frequently used word in the English language; studies and analyses of texts have found it to account for seven percent of all printed English-language words. It is derived from gendered articles in Old English which combined in Middle English and now has a single form used with nouns of any gender. The word can be used with both singular and plural nouns, and with a noun that starts with any letter. This is different from many other languages, which have different forms of the definite article for different genders or numbers. Pronunciation In most dialects, "the" is pronounced as (with the voiced dental fricative followed by a schwa) when followed by a consonant sound, and as (homophone of the archaic pronoun ''thee'') ...
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Unit 731
, short for Manchu Detachment 731 and also known as the Kamo Detachment and the Ishii Unit, was a covert biological and chemical warfare research and development unit of the Imperial Japanese Army that engaged in lethal human experimentation and biological weapons manufacturing during the Second Sino-Japanese War (1937–1945) and World War II. Estimates vary as to how many were killed. Between 1936 and 1945, roughly 14,000 victims were murdered in Unit 731. It is estimated that at least 200,000 individuals have died due to infectious illnesses caused by the activities of Unit 731 and its affiliated research facilities. It was based in the Pingfang district of Harbin, the largest city in the Japanese puppet state of Manchukuo (now Northeast China) and had active branch offices throughout China and Southeast Asia. Established in 1936, Unit 731 was responsible for some of the most notorious war crimes committed by the Japanese armed forces. It routinely conducted tests on p ...
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Interrogational Torture
Interrogational torture is the use of torture to obtain information in interrogation, as opposed to the use of torture to extract a forced confession, regardless of whether it is true or false. Torture has been used throughout history during interrogation, although it is now illegal and a violation of international law. Beyond torture's moral repugnance, most experts who study interrogation consider torture an ineffective and counterproductive means of gathering accurate information, because it frequently generates false or misleading information and impairs subsequent information collection. Investigation of effectiveness Governments that have used torture for interrogation on a large scale have not disclosed systematic information on how their torture programs were carried out, hampering efforts to investigate their effectiveness by those who lack access to classified information. Young and Kearns state that "Experiments on whether or not torture is effective are extremely cha ...
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