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Romulus, Remus, And Khaleesi
The Colossal Biosciences Dire Wolf Project is a project by Colossal Biosciences Inc. with the goal of replicating the phenotype of the extinct dire wolf (''Aenocyon dirus'') by genetic engineering. As of 2025, they had produced three genetically modified gray wolves (''Canis lupus'') beyond infancy, named: ''Romulus'', ''Remus'', and ''Khaleesi''. The project has received major criticism for the use of the term "Dire Wolf" for the project, as the genetically modified grey wolves cannot be equated as dire wolves (see ). Romulus, Remus, and Khaleesi ''Romulus'', ''Remus'', and ''Khaleesi'' are three genetically modified gray wolves, intended to mimic the extinct dire wolf. The two former are named after Romulus and Remus of Roman myth, and the latter after the literary character Daenerys Targaryen (''Khaleesi'') from George R. R. Martin's book series ''A Song of Ice and Fire''. Romulus and Remus were born on October 1, 2024; Colossal claims that the two males represent the fi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Colossal Biosciences
Colossal Biosciences Inc. is an American biotechnology and genetic engineering company working to de-extinct several extinct animals, including the woolly mammoth, the Tasmanian tiger, the northern white rhinoceros, the dire wolf, and the dodo. In 2023, it stated that it wants to have woolly mammoth hybrid calves by 2028, and wants to reintroduce them to the Arctic tundra habitat. Likewise, it launched the Tasmanian Thylacine Advisory Committee, a thylacine research project to release Tasmanian tiger joeys back to their original Tasmanian and broader Australian habitat after a period of observation in captivity. The company develops genetic engineering and reproductive technology for conservation biology. It was founded in 2021 by Harvard geneticist George Church and billionaire entrepreneur Ben Lamm. It is based in Dallas, Texas. History Foundation In a 2008 interview with ''The New York Times'', George Church first expressed his interest in engineering a hybrid Asian elephan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ancient DNA
Ancient DNA (aDNA) is DNA isolated from ancient sources (typically Biological specimen, specimens, but also environmental DNA). Due to degradation processes (including Crosslinking of DNA, cross-linking, deamination and DNA fragmentation, fragmentation) ancient DNA is more degraded in comparison with present-day genetic material. Genetic material has been recovered from paleo/archaeological and historical skeletal material, Mummy, mummified tissues, archival collections of non-frozen medical specimens, preserved plant remains, ice and from permafrost cores, marine and lake sediments and Excavation (archaeology), excavation dirt. Even under the best preservation conditions, there is an upper boundary of 0.4–1.5 million years for a sample to contain sufficient DNA for sequencing technologies. The oldest DNA sequenced from physical specimens are from mammoth molars in Siberia over 1 million years old. In 2022, two-million-year-old genetic material was recovered from sediments in G ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Egg Cell
The egg cell or ovum (: ova) is the female Reproduction, reproductive cell, or gamete, in most anisogamous organisms (organisms that reproduce sexually with a larger, female gamete and a smaller, male one). The term is used when the female gamete is not capable of movement (non-motile). If the male gamete (sperm) is capable of movement, the type of sexual reproduction is also classified as oogamous. A nonmotile female gamete formed in the oogonium of some algae, fungi, oomycetes, or bryophytes is an oosphere. When fertilized, the oosphere becomes the oospore. When egg and sperm fuse together during fertilisation, a diploid cell (the zygote) is formed, which rapidly grows into a new organism. History While the non-mammalian animal egg was obvious, the doctrine ''ex ovo omne vivum'' ("every living [animal comes from] an egg"), associated with William Harvey (1578–1657), was a rejection of spontaneous generation and preformationism as well as a bold assumption that mammals als ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dog Coat Genetics
Dogs have a wide range of coat colors, patterns, textures and lengths. Dog coat qualities are governed by how genes are passed from dogs to their puppies and how those genes are expressed in each dog. Dogs have about 19,000 genes in their genome but only a handful affect the physical variations in their coats. Dogs have two copies of most genes, one from the dog's mother and one from its father. Genes of interest have more than one version, or allele. Usually only one or a small number of alleles exist for each gene. In any one Locus (genetics), gene locus a dog will either be homozygous where the gene is made of two identical alleles (one from its mother and one its father) or heterozygous where the gene is made of two different alleles (one inherited from each parent). To understand genetically why a dog's coat physically looks the way it does requires an understanding of only a handful of canine coat genes and their alleles. For example, to understand how a black and white greyh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CRISPR Gene Editing
CRISPR gene editing (; pronounced like "crisper"; an abbreviation for "clustered regularly interspaced short palindromic repeats") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified. It is based on a simplified version of the bacterial CRISPR-Cas9 antiviral defense system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing existing genes to be removed or new ones added ''in vivo''. The technique is considered highly significant in biotechnology and medicine as it enables editing genomes ''in vivo'' and is precise, cost-effective, and efficient. It can be used in the creation of new medicines, agriculture, agricultural products, and genetically modified organisms, or as a means of controlling pathogens and pest control, pests. It also offers potential in the treatment of inherited genetic diseases as well as diseases arisi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CRISPR
CRISPR (; acronym of clustered regularly interspaced short palindromic repeats) is a family of DNA sequences found in the genomes of prokaryotic organisms such as bacteria and archaea. Each sequence within an individual prokaryotic CRISPR is derived from a DNA fragment of a bacteriophage that had previously infected the prokaryote or one of its ancestors. These sequences are used to detect and destroy DNA from similar bacteriophages during subsequent infections. Hence these sequences play a key role in the antiviral (i.e. anti- phage) defense system of prokaryotes and provide a form of heritable, acquired immunity. CRISPR is found in approximately 50% of sequenced bacterial genomes and nearly 90% of sequenced archaea. Cas9 (or "CRISPR-associated protein 9") is an enzyme that uses CRISPR sequences as a guide to recognize and open up specific strands of DNA that are complementary to the CRISPR sequence. Cas9 enzymes together with CRISPR sequences form the basis of a technology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New York Times
''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of the longest-running newspapers in the United States, the ''Times'' serves as one of the country's Newspaper of record, newspapers of record. , ''The New York Times'' had 9.13 million total and 8.83 million online subscribers, both by significant margins the List of newspapers in the United States, highest numbers for any newspaper in the United States; the total also included 296,330 print subscribers, making the ''Times'' the second-largest newspaper by print circulation in the United States, following ''The Wall Street Journal'', also based in New York City. ''The New York Times'' is published by the New York Times Company; since 1896, the company has been chaired by the Ochs-Sulzberger family, whose current chairman and the paper's publ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New Yorker
''The New Yorker'' is an American magazine featuring journalism, commentary, criticism, essays, fiction, satire, cartoons, and poetry. It was founded on February 21, 1925, by Harold Ross and his wife Jane Grant, a reporter for ''The New York Times''. Together with entrepreneur Raoul H. Fleischmann, they established the F-R Publishing Company and set up the magazine's first office in Manhattan. Ross remained the editor until his death in 1951, shaping the magazine's editorial tone and standards. ''The New Yorker''s fact-checking operation is widely recognized among journalists as one of its strengths. Although its reviews and events listings often focused on the Culture of New York City, cultural life of New York City, ''The New Yorker'' gained a reputation for publishing serious essays, long-form journalism, well-regarded fiction, and humor for a national and international audience, including work by writers such as Truman Capote, Vladimir Nabokov, and Alice Munro. In the late ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Time (magazine)
''Time'' (stylized in all caps as ''TIME'') is an American news magazine based in New York City. It was published Weekly newspaper, weekly for nearly a century. Starting in March 2020, it transitioned to every other week. It was first published in New York City on March 3, 1923, and for many years it was run by its influential co-founder, Henry Luce. A European edition (''Time Europe'', formerly known as ''Time Atlantic'') is published in London and also covers the Middle East, Africa, and, since 2003, Latin America. An Asian edition (''Time Asia'') is based in Hong Kong. The South Pacific edition, which covers Australia, New Zealand, and the Pacific Islands, is based in Sydney. Since 2018, ''Time'' has been owned by Salesforce founder Marc Benioff, who acquired it from Meredith Corporation. Benioff currently publishes the magazine through the company Time USA, LLC. History 20th century ''Time'' has been based in New York City since its first issue published on March 3, 1923 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Idaho
Idaho ( ) is a landlocked U.S. state, state in the Pacific Northwest and Mountain states, Mountain West subregions of the Western United States. It borders Montana and Wyoming to the east, Nevada and Utah to the south, and Washington (state), Washington and Oregon to the west; the state shares a small portion of the Canada–United States border to the north with the Canadian province of British Columbia. Idaho's State capital (United States), state capital and largest city is Boise, Idaho, Boise. With an area of , Idaho is the List of U.S. states and territories by area, 14th-largest state by land area. The state has a population of approximately two million people; it ranks as the List of U.S. states and territories by population, 13th-least populous and the List of U.S. states by population density, seventh-least densely populated of the List of US states, 50 U.S. states. For thousands of years, and prior to European colonization, Idaho had been inhabited by Native American ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Falls, Idaho
American Falls is a city in and the county seat of Power County, Idaho, United States. The population was 4,568 at the time of the 2020 census. History American Falls was a landmark waterfall on the Snake River, named after a party of American trappers whose boat went over the falls. The Wilson Price Hunt expedition in 1811 camped at the falls one night and the expedition of John C. Frémont was here in 1843. The Oregon Trail passed north of town, through the present-day reservoir. Power plants first sprang up at the falls in 1901. American Falls was the first town in the U.S. to be entirely relocated. It was moved in 1925 to facilitate construction of the nearby American Falls Dam. The old townsite sits at the bottom of the reservoir, northwest of the present city. A larger dam was completed in 1978, downstream from the deteriorating 1927 structure, which was later demolished. Geography According to the United States Census Bureau, the city has a total area of , all of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ohio
Ohio ( ) is a U.S. state, state in the Midwestern United States, Midwestern region of the United States. It borders Lake Erie to the north, Pennsylvania to the east, West Virginia to the southeast, Kentucky to the southwest, Indiana to the west, and Michigan to the northwest. Of the 50 List of states and territories of the United States, U.S. states, it is the List of U.S. states and territories by area, 34th-largest by area. With a population of nearly 11.9 million, Ohio is the List of U.S. states and territories by population, seventh-most populous and List of U.S. states and territories by population density, tenth-most densely populated state. Its List of capitals in the United States, capital and List of cities in Ohio, most populous city is Columbus, Ohio, Columbus, with the two other major Metropolitan statistical area, metropolitan centers being Cleveland and Cincinnati, alongside Dayton, Ohio, Dayton, Akron, Ohio, Akron, and Toledo, Ohio, Toledo. Ohio is nicknamed th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
