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Responsive Neurostimulation Device
Responsive neurostimulation device is a medical device that senses changes in a person's body and uses neurostimulation to respond in the treatment of disease. The FDA has approved devices for use in the United States in the treatment of epileptic seizures and chronic pain conditions. Devices are being studied for use in the treatment of essential tremor, Parkinson's disease, Tourette's syndrome, depression, obesity, and post-traumatic stress disorder. Medical uses Epilepsy The use of neurostimulation to treat epileptic seizures is only recommended in those who have failed multiple medications for the treatment of their seizures. The NeuroPace RNS system was approved for use by the FDA in 2013 and is the only medical device for epilepsy that uses responsive neurostimulation. The device is surgically implanted into the patient's head with electrical leads placed near the site in the brain that is believed to be the origin of the patient's seizures. These leads record electri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinal Cord Stimulator
A spinal cord stimulator (SCS) or dorsal column stimulator (DCS) is a type of implantable neuromodulation device (sometimes called a "pain pacemaker") that is used to send electrical signals to select areas of the spinal cord (dorsal columns) for the treatment of certain pain conditions. SCS is a consideration for people who have a pain condition that has not responded to more conservative therapy. There are also spinal cord stimulators under research and development that could enable patients with spinal cord injury to walk again via epidural electrical stimulation (EES). Medical uses The most common use of SCS is Failed back syndrome, failed back surgery syndrome (FBSS) in the United States and peripheral ischemic pain in Europe. As of 2014 the FDA had approved SCS as a treatment for FBSS, chronic pain, complex regional pain syndrome, intractable angina, as well as visceral abdominal and perineal pain and pain in the extremities from nerve damage. Once a person has had a psych ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcranial Direct-current Stimulation
Transcranial direct current stimulation (tDCS) is a form of neuromodulation that uses constant, low direct current delivered via electrodes on the head. This type of neurotherapy was originally developed to help patients with brain injuries or neuropsychiatric conditions such as major depressive disorder. It can be contrasted with cranial electrotherapy stimulation, which generally uses alternating current the same way, as well as transcranial magnetic stimulation. Research shows increasing evidence for tDCS as a treatment for depression. There is mixed evidence about whether tDCS is useful for cognitive enhancement in healthy people. There is no strong evidence that tDCS is useful for memory deficits in Parkinson's disease and Alzheimer's disease, non-neuropathic pain, nor for improving arm or leg functioning and muscle strength in people recovering from a stroke. There is emerging supportive evidence for tDCS in the management of schizophreniaespecially for negative symptoms. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organization For Human Brain Mapping
The Organization for Human Brain Mapping (OHBM) is an organization of scientists with the main aim of organizing an annual meeting ("Annual Meeting of the Organization for Human Brain Mapping"). The organization was established in 1995 at its first conference, which was a Paris satellite meeting of the meeting of the International Society for Cerebral Blood Flow and Metabolism (ISCBFM) in Cologne. Although the 1999 meetings of the two societies were coordinated, ISCBFM and OHBM have now split completely. The organizers of the Paris meeting were Bernard Mazoyer, Rüdiger Seitz and Per Roland. OHBM's Mission statement, stated mission is "to advance the understanding of the anatomical and functional organization of the human brain" by bringing "together scientists of various backgrounds who are engaged in investigations relevant to human brain organization" and engaging "in other activities to facilitate communication among these scientists and promote education in human brain organi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroprosthetics
Neuroprosthetics (also called neural prosthetics) is a discipline related to neuroscience and biomedical engineering concerned with developing neural prostheses. They are sometimes contrasted with a brain–computer interface, which connects the brain to a computer rather than a device meant to replace missing biological functionality. Neural prostheses are a series of devices that can substitute a motor, sensory or cognitive modality that might have been damaged as a result of an injury or a disease. Cochlear implants provide an example of such devices. These devices substitute the functions performed by the eardrum and stapes while simulating the frequency analysis performed in the cochlea. A microphone on an external unit gathers the sound and processes it; the processed signal is then transferred to an implanted unit that stimulates the auditory nerve through a microelectrode array. Through the replacement or augmentation of damaged senses, these devices are intended to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuromodulation (medicine)
Neuromodulation is "the alteration of nerve activity through targeted delivery of a stimulus, such as electrical stimulation or chemical agents, to specific neurological sites in the body". It is carried out to normalize – or modulate – nervous tissue function. Neuromodulation is an evolving therapy that can involve a range of electromagnetic stimuli such as a magnetic field (Transcranial magnetic stimulation, rTMS), an electric current, or a drug instilled directly in the subdural space (intrathecal drug delivery). Emerging applications involve targeted introduction of genes or gene regulators and light (optogenetics), and by 2014, these had been at minimum demonstrated in mammalian models, or first-in-human data had been acquired. The most clinical experience has been with electrical stimulation. Neuromodulation, whether electrical or magnetic, employs the body's natural biological response by stimulating nerve cell activity that can influence populations of nerves by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electroconvulsive Therapy
Electroconvulsive therapy (ECT) is a psychiatry, psychiatric treatment that causes a generalized seizure by passing electrical current through the brain. ECT is often used as an intervention for mental disorders when other treatments are inadequate. Conditions responsive to ECT include major depressive disorder, mania, and catatonia.FDAFDA Executive Summary Prepared for the January 27–28, 2011 meeting of the Neurological Devices Panel Meeting to Discuss the Classification of Electroconvulsive Therapy Devices (ECT). Quote, p. 38: "Three major practice guidelines have been published on ECT. These guidelines include: APA Task Force on ECT (2001); Third report of the Royal College of Psychiatrists' Special Committee on ECT (2004); National Institute for Health and Clinical Excellence (NICE 2003; NICE 2009). There is significant agreement between the three sets of recommendations." The general physical risks of ECT are similar to those of brief general anesthesia. Immediately fol ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cranial Electrotherapy Stimulation
Cranial electrotherapy stimulation (CES) is a form of neurostimulation that delivers a small, pulsed, alternating current via electrodes on the head. CES is used with the intention of treating a variety of conditions such as anxiety, clinical depression, depression and insomnia. CES has been suggested as a possible treatment for headaches, fibromyalgia, smoking cessation, and opiate withdrawal, but there is little evidence of effectiveness for many of these conditions and the evidence for use in acute depression (mood), depression is not sufficient to justify it. Medical uses A 2014 Cochrane review found insufficient evidence to determine whether or not CES with alternating current is safe and effective for treating depression. The FDA came to the same conclusion in December 2019. A 2018 systematic review found that evidence is insufficient that CES has clinically important effects on fibromyalgia, headache, neuromusculoskeletal pain, degenerative joint pain, depression, or insomn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain Implant
Brain implants, often referred to as neural implants, are technological devices that connect directly to a biological subject's brain – usually placed on the surface of the brain, or attached to the brain's cortex. A common purpose of modern brain implants and the focus of much current research is establishing a biomedical prosthesis circumventing areas in the brain that have become dysfunctional after a stroke or other head injuries. This includes sensory substitution, e.g., in vision. Other brain implants are used in animal experiments simply to record brain activity for scientific reasons. Some brain implants involve creating interfaces between neural systems and computer chips. This work is part of a wider research field called brain–computer interfaces. (Brain–computer interface research also includes technology such as EEG arrays that allow interface between mind and machine but do not require direct implantation of a device.) Neural implants such as deep brain stim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neural Network
A neural network is a group of interconnected units called neurons that send signals to one another. Neurons can be either biological cells or signal pathways. While individual neurons are simple, many of them together in a network can perform complex tasks. There are two main types of neural networks. *In neuroscience, a '' biological neural network'' is a physical structure found in brains and complex nervous systems – a population of nerve cells connected by synapses. *In machine learning, an '' artificial neural network'' is a mathematical model used to approximate nonlinear functions. Artificial neural networks are used to solve artificial intelligence problems. In biology In the context of biology, a neural network is a population of biological neurons chemically connected to each other by synapses. A given neuron can be connected to hundreds of thousands of synapses. Each neuron sends and receives electrochemical signals called action potentials to its conne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Deep Brain Stimulation
Deep brain stimulation (DBS) is a type of neurostimulation therapy in which an implantable pulse generator is stereotactic surgery, surgically implanted subcutaneous tissue, below the skin of the chest and connected by Lead (electronics), leads to the brain to deliver controlled electrical charge, electrical impulses. These charges therapeutically disrupt and promote dysfunctional nervous system circuits bidirectionally in both ante- and retrograde signaling, retrograde directions. Though first developed for Parkinsonian tremor, the technology has since been adapted to a wide variety of chronic neurologic disorders. The usage of electrical stimulation to treat neurologic disorders dates back thousands of years to ancient Greece and Early Dynastic Period (Egypt), dynastic Egypt. The distinguishing feature of DBS, however, is that by taking advantage of the portability of lithium-ion battery technology, it is able to be used long term without the patient having to be Electrical wir ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Position
Human positions refer to the different physical configurations that the human body can take. There are several synonyms that refer to human positioning, often used interchangeably, but having specific nuances of meaning. *''Position'' is a general term for a configuration of the human body. *''Posture'' means an intentionally or habitually assumed position. *''Pose'' implies an artistic, aesthetic, athletic, or spiritual intention of the position. *''Attitude'' refers to postures assumed for purpose of imitation, intentional or not, as well as in some standard collocations in reference to some distinguished types of posture: " Freud never assumed a fencer's attitude, yet almost all took him for a swordsman." *''Bearing'' refers to the manner of the posture, as well as of gestures and other aspects of the conduct taking place. Basic positions While not moving, a human is usually in one of the following basic positions: All-fours This is the static form of crawling which is a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
