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Ouchterlony Double Immunodiffusion
Ouchterlony double immunodiffusion (also known as passive double immunodiffusion) is an immunological technique used in the detection, identification and quantification of antibodies and antigens, such as immunoglobulins and extractable nuclear antigens. The technique is named after Örjan Ouchterlony, the Swedish physician who developed the test in 1948 to evaluate the production diphtheria toxins from isolated bacteria. Procedure A gel plate is cut to form a series of holes ("wells") in an agar or agarose gel. A sample extract of interest (for example human cells harvested from tonsil tissue) is placed in one well, and sera or purified antibodies are placed in another well and the plate left for 48 hours to develop. During this time the antigens in the sample extract and the antibodies each diffuse out of their respective wells. Where the two diffusion fronts meet, if any of the antibodies recognize any of the antigens, they will bind to the antigens and form an immune comp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ouchterlony Double Diffusion
Ochterlony or Ouchterlony may refer to: * Ouchterlony Valley, or O' Valley, a town in Gudalur Taluk, Nilgiris district, Tamil Nadu, India People with the surname Ochterlony *David Ochterlony (1758–1825), Massachusetts-born general of the East India Company in British India * David Ochterlony Dyce Sombre (1808–1851), an Anglo-Indian held to be the first person of Asian descent to be elected to the British Parliament * John Ochterlony (1667–1742), Anglican clergyman in the Scottish Episcopal Church and Bishop of Brechin *Matthew Ochterlony (1880–1946), Scottish peer and architect * Robert Ochterlony, Anglican Dean of Brechin in the 1720s Ouchterlony *Örjan Ouchterlony (1914–2004), Swedish bacteriologist and immunologist See also *Ochterlony baronets and the Ochterlony Baronetcy, two titles in the Baronetage of the United Kingdom *Ochterlony Monument or Shaheed Minar, a monument in Kolkata. India *Ouchterlony double immunodiffusion Ouchterlony double immunodiffusion ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Preciptin
A precipitin is an antibody which can precipitate out of a solution upon antigen binding. Precipitin reaction The precipitin reaction provided the first quantitative assay for antibody. The precipitin reaction is based upon the interaction of antigen with antibody leading to the production of antigen-antibody complexes. To produce a precipitin reaction, varying amounts of soluble antigen are added to a fixed amount of serum containing antibody. As the amount of antigen added: * In the zone of antibody excess, each molecule of antigen is bound extensively by antibody and crosslinked to other molecules of antigen. The average size of antibody-antigen complex is small; cross-linking between antigen molecules by antibody is rare. * In the zone of equivalence, the formation of precipitin complexes is optimal. Extensive lattices of antigen and antibody are formed by cross-linking. * At high concentrations of antigen, the average size of antibody-antigen complexes is once again small be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amrita Vishwa Vidyapeetham
Amrita Vishwa Vidyapeetham (or Amrita University) is a private deemed university based in Coimbatore, India. It currently has 7 campuses with 16 constituent schools across the Indian states of Tamil Nadu, Kerala, Andhra Pradesh and Karnataka with the headquarters at Ettimadai, Coimbatore, Tamil Nadu. It offers a total of 207 undergraduate, postgraduate, integrated-degree, dual-degree, doctoral programs in engineering and technology, medicine, business, arts and culture, sciences, biotechnology, agricultural sciences, allied health sciences, Ayurveda, dentistry, pharmacy, nursing, nano-sciences, commerce, humanities and social sciences, law, literature, spiritual studies, philosophy, education, sustainable development, mass communication and social work. History The university was founded with the opening of Amrita School of Engineering, Coimbatore in 1994 by Mata Amritanandamayi Devi and is managed by her international humanitarian organisation Mata Amritanandamayi Math. In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, Irvine School Of Medicine
The University of California, Irvine School of Medicine (UC Irvine School of Medicine or UCI School of Medicine) is an LCME accredited medical school, co-located in Orange County's cities of Irvine on the University of California, Irvine campus and Orange at the UC Irvine Medical Center. Of the medical schools evaluated for its 2013 edition (released March 13, 2012), ''U.S News & World Report'' ranked the school 43rd in Research and 61st in Primary Care. The school was founded in 1896 by A.C. Moore and is the oldest continually operating medical school in the greater Los Angeles area. The school is affiliated with UC Irvine Medical Center and the Children's Hospital of Orange County. History Although the School of Medicine joined UC Irvine in 1967, its history goes back more than 100 years. In 1896, the Pacific College of Osteopathy was founded in the city of Anaheim. Upon moving to Los Angeles in 1904, and through a merger with the Los Angeles College of Osteopathy, the Cali ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Google Books
Google Books (previously known as Google Book Search, Google Print, and by its code-name Project Ocean) is a service from Google Inc. that searches the full text of books and magazines that Google has scanned, converted to text using optical character recognition (OCR), and stored in its digital database.The basic Google book link is found at: https://books.google.com/ . The "advanced" interface allowing more specific searches is found at: https://books.google.com/advanced_book_search Books are provided either by publishers and authors through the Google Books Partner Program, or by Google's library partners through the Library Project. Additionally, Google has partnered with a number of magazine publishers to digitize their archives. The Publisher Program was first known as Google Print when it was introduced at the Frankfurt Book Fair in October 2004. The Google Books Library Project, which scans works in the collections of library partners and adds them to the digital invent ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wiley-Blackwell
Wiley-Blackwell is an international scientific, technical, medical, and scholarly publishing business of John Wiley & Sons. It was formed by the merger of John Wiley & Sons Global Scientific, Technical, and Medical business with Blackwell Publishing in 2007.About Wiley-Blackwell John Wiley & Sons, Inc. Wiley-Blackwell is now an imprint that publishes a diverse range of academic and professional fields, including , , , |
England
England is a country that is part of the United Kingdom. It shares land borders with Wales to its west and Scotland to its north. The Irish Sea lies northwest and the Celtic Sea to the southwest. It is separated from continental Europe by the North Sea to the east and the English Channel to the south. The country covers five-eighths of the island of Great Britain, which lies in the North Atlantic, and includes over 100 smaller islands, such as the Isles of Scilly and the Isle of Wight. The area now called England was first inhabited by modern humans during the Upper Paleolithic period, but takes its name from the Angles, a Germanic tribe deriving its name from the Anglia peninsula, who settled during the 5th and 6th centuries. England became a unified state in the 10th century and has had a significant cultural and legal impact on the wider world since the Age of Discovery, which began during the 15th century. The English language, the Anglican Church, and Engli ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford
Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the University of Oxford, the oldest university in the English-speaking world; it has buildings in every style of English architecture since late Anglo-Saxon. Oxford's industries include motor manufacturing, education, publishing, information technology and science. History The history of Oxford in England dates back to its original settlement in the Saxon period. Originally of strategic significance due to its controlling location on the upper reaches of the River Thames at its junction with the River Cherwell, the town grew in national importance during the early Norman period, and in the late 12th century became home to the fledgling University of Oxford. The city was besieged during The Anarchy in 1142. The university rose to dom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
APMIS ".
It was formed by the 1988 union of the three sections of ''Acta Pathologica, Microbiologica, et Immunologica Scandinavica'': ''Section A, Pathology'', ''Section B, Microbiology'', and ''Section C, Immunology''. The original journals dated from 1924, originally published as ''Acta Pathologica et Microbiologica Scandinavica''. ...
''APMIS'', formerly known as ''Acta Pathologica, Microbiologica, et Immunologica Scandinavica'', is a monthly medical journal published on behalf of the Scandinavian Societies for Medical Microbiology and Pathology by Wiley Munksgaard. Its stated aim is to "publish original research in the fields of pathology, microbiology and immunology, and from related developing areas of modern biomedicine Biomedicine (also referred to as Western medicine, mainstream medicine or conventional medicine) [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Totowa, New Jersey
Totowa (pronounced "TO-tuh-wuh" ) is a borough in Passaic County, New Jersey, United States. As of the 2010 United States census, the borough's population was 10,844,DP-1 - Profile of General Population and Housing Characteristics: 2010 for Totowa borough, Passaic County, New Jersey . Accessed August 16, 2012. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Humana Press
Humana Press was an American academic publisher of science, technology, and medical books and journals founded in 1976. It was bought by Springer Science+Business Media in 2006. History Humana published more than 100 new books and 25 journals per year, with a back list of approximately 1,500 titles in areas such as molecular biology, neuroscience, cancer research, pathology, and medicine. The company was founded in 1976 in Clifton, New Jersey by Thomas L. Lanigan and his wife, Julia Lanigan, both chemists, and published its first book in 1977. The company was acquired by Springer Science+Business Media in the fall of 2006 and continues to publish titles in a range of book series under the Humana Press imprint. "Springer Buys Humana; Blackwell Adds Brandywine." September 5, 2006. The company's employees r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prozone Phenomenon
The hook effect refers to the prozone phenomenon, also known as antibody excess or the Postzone phenomenon, also known as antigen excess. It is an immunology, immunologic phenomenon whereby the effectiveness of antibody, antibodies to form immune complexes can be impaired when concentrations of an antibody or an antigen are very high. The formation of immune complexes stops increasing with greater concentrations and then decreases at extremely high concentrations, producing a hook shape on a graph of a function, graph of measurements. An important practical relevance of the phenomenon is as a type of interference that plagues certain immunoassays and nephelometry, nephelometric assays, resulting in false negatives or inaccurately low results. Other common forms of interference include antibody interference, cross-reactivity and signal interference. The phenomenon is caused by very high concentrations of a particular analyte or antibody and is most prevalent in one-step (sandwich) im ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
