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Neuroplasticity
Neuroplasticity, also known as neural plasticity or just plasticity, is the ability of neural networks in the brain to change through neurogenesis, growth and reorganization. Neuroplasticity refers to the brain's ability to reorganize and rewire its neural connections, enabling it to adapt and function in ways that differ from its prior state. This process can occur in response to learning new skills, experiencing environmental changes, recovering from injuries, or adapting to sensory or cognitive deficits. Such adaptability highlights the dynamic and ever-evolving nature of the brain, even into adulthood. These changes range from individual neuron pathways making new connections, to systematic adjustments like cortical remapping or neural oscillation. Other forms of neuroplasticity include homologous area adaptation, cross modal reassignment, map expansion, and compensatory masquerade. Examples of neuroplasticity include neural circuit, circuit and network changes that result fr ...
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Activity-dependent Plasticity
Activity-dependent plasticity is a form of functional and structural neuroplasticity that arises from the use of cognitive functions and personal experience. Hence, it is the biological basis for learning and the formation of new memory, memories. Activity-dependent plasticity is a form of neuroplasticity that arises from intrinsic or endogenous activity, as opposed to forms of neuroplasticity that arise from extrinsic or exogenous factors, such as electrical brain stimulation- or drug-induced neuroplasticity. The brain's ability to remodel itself forms the basis of the brain's capacity to retain memories, improve motor function, and enhance comprehension and speech amongst other things. It is this trait to retain and form memories that is associated with neural plasticity and therefore many of the functions individuals perform on a daily basis. This plasticity occurs as a result of changes in gene expression which are triggered by signaling cascades that are activated by various s ...
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Cortical Remapping
Cortical remapping, also referred to as cortical reorganization, is the process by which an existing cortical map is affected by a stimulus resulting in the creating of a 'new' cortical map. Every part of the body is connected to a corresponding area in the brain which creates a cortical map. When something happens to disrupt the cortical maps such as an amputation or a change in neuronal characteristics, the map is no longer relevant. The part of the brain that is in charge of the amputated limb or neuronal change will be dominated by adjacent cortical regions that are still receiving input, thus creating a remapped area. Remapping can occur in the sensory or motor system. The mechanism for each system may be quite different. Cortical remapping in the somatosensory system happens when there has been a decrease in sensory input to the brain due to deafferation, deafferentation or amputation, as well as a sensory input increase to an area of the brain. Motor system remapping receive ...
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Learning
Learning is the process of acquiring new understanding, knowledge, behaviors, skills, value (personal and cultural), values, Attitude (psychology), attitudes, and preferences. The ability to learn is possessed by humans, non-human animals, and some machine learning, machines; there is also evidence for some kind of learning in certain plants. Some learning is immediate, induced by a single event (e.g. being burned by a Heat, hot stove), but much skill and knowledge accumulate from repeated experiences. The changes induced by learning often last a lifetime, and it is hard to distinguish learned material that seems to be "lost" from that which cannot be retrieved. Human learning starts at birth (it might even start before) and continues until death as a consequence of ongoing interactions between people and their environment. The nature and processes involved in learning are studied in many established fields (including educational psychology, neuropsychology, experimental psycho ...
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Neural Network
A neural network is a group of interconnected units called neurons that send signals to one another. Neurons can be either biological cells or signal pathways. While individual neurons are simple, many of them together in a network can perform complex tasks. There are two main types of neural networks. *In neuroscience, a '' biological neural network'' is a physical structure found in brains and complex nervous systems – a population of nerve cells connected by synapses. *In machine learning, an '' artificial neural network'' is a mathematical model used to approximate nonlinear functions. Artificial neural networks are used to solve artificial intelligence problems. In biology In the context of biology, a neural network is a population of biological neurons chemically connected to each other by synapses. A given neuron can be connected to hundreds of thousands of synapses. Each neuron sends and receives electrochemical signals called action potentials to its conne ...
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Karl Lashley
Karl Spencer Lashley (June 7, 1890 – August 7, 1958) was an American psychologist and behaviorist remembered for his contributions to the study of learning and memory. A ''Review of General Psychology'' survey, published in 2002, ranked Lashley as the 61st most cited psychologist of the 20th century. Early life and education Lashley was born on June 7, 1890, in the town of Davis, West Virginia. He was the only child of Charles and Maggie Lashley. He grew up in a middle-class family with a reasonably comfortable life. Lashley's father held various local political positions. His mother was a stay-at-home parent, and had a vast collection of books in the home. She brought in women from the community, whom she would teach various subjects. This is no doubt what gave Lashley his love of learning. Lashley has always held his family in high regard. He has said that his father was a kind man. Lashley's mother was a strong advocate of schooling, and she encouraged Lashley intellectuall ...
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Peripheral Nervous System
The peripheral nervous system (PNS) is one of two components that make up the nervous system of Bilateria, bilateral animals, with the other part being the central nervous system (CNS). The PNS consists of nerves and ganglia, which lie outside the brain and the spinal cord. The main function of the PNS is to connect the CNS to the Limb (anatomy), limbs and Organ (anatomy), organs, essentially serving as a relay between the brain and spinal cord and the rest of the body. Unlike the CNS, the PNS is not protected by the vertebral column and skull, or by the blood–brain barrier, which leaves it exposed to toxins. The peripheral nervous system can be divided into a somatic nervous system, somatic division and an autonomic nervous system, autonomic division. Each of these can further be differentiated into a sensory and a motor sector. In the somatic nervous system, the cranial nerves are part of the PNS with the exceptions of the olfactory nerve and epithelia and the optic nerve (c ...
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Central Nervous System
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain, spinal cord and retina. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all parts of the bodies of bilateria, bilaterally symmetric and triploblastic animals—that is, all multicellular animals except sponges and Coelenterata, diploblasts. It is a structure composed of nervous tissue positioned along the Anatomical_terms_of_location#Rostral,_cranial,_and_caudal, rostral (nose end) to caudal (tail end) axis of the body and may have an enlarged section at the rostral end which is a brain. Only arthropods, cephalopods and vertebrates have a true brain, though precursor structures exist in onychophorans, gastropods and lancelets. The rest of this article exclusively discusses the vertebrate central nervous system, which is radically distinct from all other animals. Overview In vertebrates, the brain and spinal ...
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Walther Spielmeyer
Walther Spielmeyer (23 April 1879 – 6 February 1935) was a German neuropathologist who was a native of Dessau. Biography He studied medicine at the University of Halle as a student of Eduard Hitzig (1838-1907). At Halle he was influenced by the work of psychiatrists Karl Heilbronner (1869-1914), Gustav Aschaffenburg (1866-1944) and pathologist Karl Joseph Eberth (1835-1926). In 1906 he relocated to Freiburg as an assistant to Alfred Hoche (1865-1943). At the suggestion of Emil Kraepelin (1856-1926), he succeeded Alois Alzheimer (1864-1915) as director of the ''Anatomisches Laboratorium der Psychiatrischen und Nervenklinik'' in Munich. At Munich he worked with Franz Nissl (1860-1919) and Felix Plaut (1877-1940). In 1928 the Rockefeller Foundation financed the Kaiser Wilhelm Institute with Spielmeyer as director of the ''Hirnpathologisches Institut''. He died of pulmonary tuberculosis on February 6, 1935. Research Spielmeyer is remembered for his research of peripheral ...
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Max Bielschowsky
Max Israel Bielschowsky (20 February 1869 – 15 August 1940) was a German neuropathologist born in Breslau. After receiving his medical doctorate from the University of Munich in 1893, he worked with Ludwig Edinger (1855–1918) at the Senckenberg Museum, Senckenberg Pathology Institute in Frankfurt-am-Main. At Senckenberg he learned histology, histological staining techniques from Carl Weigert (1845–1904). From 1896 to 1904 he worked in Emanuel Mendel's (1839–1907) psychiatric laboratory in Berlin. In 1904 he joined Oskar Vogt (1870–1959) at the neurobiology, neurobiological laboratory at the University of Berlin, where he remained until 1933. Later in his career he worked at the psychiatric clinic at the University of Utrecht, and at the Cajal Institute in Madrid. He emigrated to the UK, where he died on 15 August 1940 in the Greater London area at 71 years of age. His oldest son, Franz David Bielschowsky, also emigrated to Sheffield, UK and subsequently to Dunedin, N ...
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Nicolas Rashevsky
Nicolas Rashevsky (November 9, 1899 – January 16, 1972) was an American theoretical physicist who was one of the pioneers of mathematical biology, and is also considered the father of mathematical biophysics and theoretical biology. Robert Rosen ''Essays on Life'' (2004) Evelyn Fox Keller ''Making Sense of Life'' pp. 82-89 Academic career He studied theoretical physics at the St. Vladimir Imperial University of Kyiv. He left Ukraine after the October Revolution, emigrating first to Turkey, then to Poland, France, and finally to the US in 1924. In USA he worked at first for the Westinghouse Research Labs in Pittsburgh where he focused on the theoretical physics modeling of the cell division and the mathematics of cell fission. He was awarded a Rockefeller Fellowship in 1934 and went to the University of Chicago to take up the appointment of assistant professor in the department of physiology. In 1938, inspired by reading On Growth and Form (1917) by D'Arcy Wentworth Tho ...
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Rhesus Monkey
The rhesus macaque (''Macaca mulatta''), colloquially rhesus monkey, is a species of Old World monkey. There are between six and nine recognised subspecies split between two groups, the Chinese-derived and the Indian-derived. Generally brown or grey in colour, it is in length with a tail and weighs . It is native to South Asia, South, Central Asia, Central, and Southeast Asia and has the widest geographic range of all non-human primates, occupying a great diversity of altitudes and habitats. The rhesus macaque is diurnality, diurnal, arboreal, and terrestrial. It is mostly herbivorous, feeding mainly on fruit, but also eating seeds, roots, buds, Bark (botany), bark, and cereals. Rhesus macaques living in cities also eat human food and trash. They are gregarious, with troops comprising 20–200 individuals. The social groups are matrilineal. Individuals communicate with a variety of facial expressions, vocalisations, body postures, and gestures. As a result of the rhesus macaq ...
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Santiago Ramón Y Cajal
Santiago Ramón y Cajal (; 1 May 1852 – 17 October 1934) was a Spanish neuroscientist, pathologist, and histologist specializing in neuroanatomy, and the central nervous system. He and Camillo Golgi received the Nobel Prize in Physiology or Medicine in 1906. Ramón y Cajal was the first Spaniard to win a scientific Nobel Prize. His original investigations of the microscopic structure of the brain made him a pioneer of modern neuroscience. Hundreds of his drawings illustrating the arborization (tree-like growth) of brain cells are still in use, since the mid-20th century, for educational and training purposes. Biography Santiago Ramón y Cajal was born on 1 May 1852, in the town of Petilla de Aragón, Navarre, Spain. As a child he was transferred many times from one school to another because of behavior that was declared poor, rebellious, and anti-authoritarian. An extreme example of his precociousness and rebelliousness at the age of eleven is his 1863 imprisonment for des ...
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