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Leo Sternbach
Leo Sternbach (May 7, 1908 – September 28, 2005) was a Polish American chemist who is credited with first synthesizing benzodiazepines, the main class of tranquilizers. Background and family Sternbach was born on May 7, 1908, in Opatija, Kingdom of Hungary, Austro-Hungarian Empire, to an upper middle class Jewish family. He had a younger brother, Giusi. Ha-Kol (Glasilo Židovske zajednice u Hrvatskoj); Sanja Dukić; Povratak velikana u rodnu Opatiju; stranica 40, 41; broj 94, svibanj / lipanj 2006. His father Michael Abracham Sternbach was from the Polish city of Przemyśl in Galicia (then part of Austria-Hungary), and his mother Piroska (née Cohn) Sternbach was from Orosháza, Hungary. Sternbach's parents met and married in Opatija where they both lived. The family lived in modest conditions, in a rented four-room apartment on the third floor of the "Vila Jadran" (Villa Adriatic), near the pharmacy owned by Sternbach's father. Sternbach attended a private German school in O ...
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Opatija
Opatija (; it, Abbazia; german: Sankt Jakobi) is a town and a municipality in Primorje-Gorski Kotar County in western Croatia. The traditional seaside resort on the Kvarner Gulf is known for its Mediterranean climate and its historic buildings reminiscent of the Austrian Riviera. Geography Opatija is located northwest of the regional capital Rijeka, about from Trieste by rail and from Pula by road. The city is geographically on the Istrian peninsula, though not in Istria County. The tourist resort is situated on the Kvarner Gulf, part of the Adriatic coast, in a sheltered position at the foot of Učka massif, with the ''Vojak'' peak reaching at a height of . cesnus, the municipality had 10,661 inhabitants in total, of which 5,715 lived in the urban settlement. The town is a popular summer and winter resort, with average high temperatures of 10 °C in winter, and 32 °C in summer. Opatija is surrounded by beautiful woods of bay laurel. The whole sea-coast to the ...
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Bielitz
Bielsko (german: Bielitz, cs, Bílsko) was until 1950 an independent town situated in Cieszyn Silesia, Poland. In 1951 it was joined with Biała Krakowska to form the new town of Bielsko-Biała. Bielsko constitutes the western part of that town. Bielsko was founded by the Cieszyn Piast dukes in the late 13th century on the grounds of village later called Stare Bielsko (''Old Bielsko''), on the Biała River. It was first mentioned in a written document in 1312. Originally settled by Germans, it became the largest German-language center (''Deutsche Sprachinsel Bielitz'') in the Duchy of Teschen, and remained so until the end of World War II. In 1572 it gained autonomy as the Duchy (State) of Bielsko. During the 18th century a rapid development of textile industry occurred, and at the beginning of the 19th century more than 500 weavers worked in the town. After the 1920 division of Cieszyn Silesia between Poland and Czechoslovakia it became, despite the protests of local Germa ...
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Diazepam
Diazepam, first marketed as Valium, is a medicine of the benzodiazepine family that acts as an anxiolytic. It is commonly used to treat a range of conditions, including anxiety, seizures, alcohol withdrawal syndrome, muscle spasms, insomnia, and restless legs syndrome. It may also be used to cause memory loss during certain medical procedures. It can be taken by mouth, inserted into the rectum, injected into muscle, injected into a vein or used as a nasal spray. When given into a vein, effects begin in one to five minutes and last up to an hour. By mouth, effects begin after 15 to 60 minutes. Common side-effects include sleepiness and trouble with coordination. Serious side effects are rare. They include increased risk of suicide, decreased breathing, and an increased risk of seizures if used too frequently in those with epilepsy. Occasionally, excitement or agitation may occur. Long-term use can result in tolerance, dependence, and withdrawal symptoms on dose reduc ...
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Chlordiazepoxide
Chlordiazepoxide, trade name Librium among others, is a sedative and hypnotic medication of the benzodiazepine class; it is used to treat anxiety, insomnia and symptoms of withdrawal from alcohol and other drugs. Chlordiazepoxide has a medium to long half-life but its active metabolite has a very long half-life. The drug has amnesic, anticonvulsant, anxiolytic, hypnotic, sedative and skeletal muscle relaxant properties. Chlordiazepoxide was patented in 1958 and approved for medical use in 1960. It was the first benzodiazepine to be synthesized and the discovery of chlordiazepoxide was by pure chance. Chlordiazepoxide and other benzodiazepines were initially accepted with widespread public approval but were followed with widespread public disapproval and recommendations for more restrictive medical guidelines for its use. Medical uses Chlordiazepoxide is indicated for the short-term (2–4 weeks) treatment of anxiety that is severe and disabling or subjecting the person to ...
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Science History Institute
The Science History Institute is an institution that preserves and promotes understanding of the history of science. Located in Philadelphia, Pennsylvania, it includes a library, museum, archive, research center and conference center. It was founded in 1982 as a joint venture of the American Chemical Society and the University of Pennsylvania, as the Center for the History of Chemistry (CHOC). The American Institute of Chemical Engineers (AIChE) became a co-founder in 1984. It was renamed the Chemical Heritage Foundation (CHF) in 1992, and moved two years later to the institution's current location, 315 Chestnut Street in Old City, Philadelphia, Old City. On December 1, 2015, CHF merged with the Life Sciences Foundation, creating an organization that covers "the history of the life sciences and biotechnology together with the history of the chemical sciences and engineering." As of February 1, 2018, the organization was renamed the Science History Institute, to reflect its wide ...
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