|
John O'Keefe (neuroscientist)
John O'Keefe (born November 18, 1939) is an American-British neuroscientist, psychologist and a professor at University College London. O'Keefe discovered place cells in the hippocampus, and that they show a specific kind of temporal coding in the form of theta phase precession. He shared the Nobel Prize in Physiology or Medicine in 2014, together with May-Britt Moser and Edvard Moser; he has received several other awards. Early life and education Born in New York City to Irish immigrant parents, O'Keefe attended Regis High School (Manhattan) and received a BA degree from the City College of New York in 1963. Neither of his parents had completed elementary school in Ireland, but his father attained a high school degree in New York. He went on to study at McGill University in Montreal, Quebec, Canada, where he obtained an MA degree in 1964, and a PhD degree in Psychology in 1967, supervised by Ronald Melzack. Career and research O'Keefe went to University College London ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New York City
New York, often called New York City (NYC), is the most populous city in the United States, located at the southern tip of New York State on one of the world's largest natural harbors. The city comprises five boroughs, each coextensive with a respective county. The city is the geographical and demographic center of both the Northeast megalopolis and the New York metropolitan area, the largest metropolitan area in the United States by both population and urban area. New York is a global center of finance and commerce, culture, technology, entertainment and media, academics, and scientific output, the arts and fashion, and, as home to the headquarters of the United Nations, international diplomacy. With an estimated population in 2024 of 8,478,072 distributed over , the city is the most densely populated major city in the United States. New York City has more than double the population of Los Angeles, the nation's second-most populous city. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychologist
A psychologist is a professional who practices psychology and studies mental states, perceptual, cognitive, emotional, and social processes and behavior. Their work often involves the experimentation, observation, and explanation, interpretation of how individuals relate to each other and to their environments. Psychologists usually acquire a bachelor's degree in psychology, followed by a master's degree or doctorate in psychology. Unlike psychiatrist, psychiatrists and psychiatric nurse-practitioners, psychologists usually cannot prescribe medication, but depending on the jurisdiction, some psychologists with additional training can be licensed to prescribe medications; qualification requirements may be different from a bachelor's degree and master's degree. Psychologists receive extensive training in psychological testing, communication techniques, scoring, interpretation, and reporting, while psychiatrists are not usually trained in psychological testing. Psychologists are a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Patrick David Wall
Patrick David Wall (25 April 1925 – 8 August 2001) was a British neuroscientist described as 'the world's leading expert on pain' and best known for the gate control theory of pain. Early life and education Wall was born in Nottingham on 25 April 1925 to Thomas Wall, the director of education for Middlesex, and his wife Ruth Cresswell. He was educated at St Paul's School, London and the University of Oxford, studying medicine at Christ Church, Oxford, where he became interested in pain. He published his first two papers, in the prominent science journals ''Brain'' and ''Nature'', at the age of 21. While at Oxford he had also helped found the British Medical Students' Journal, partially to help campaign for the introduction of the National Health Service (NHS). He graduated in 1948, by which time he had published three papers in prominent science journals. Career and research After graduating, he spent a short time treating holocaust survivors and refugees in mainland Euro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Postdoctoral Research
A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). Postdocs most commonly, but not always, have a temporary academic appointment, sometimes in preparation for an academic faculty position. According to data from the US National Science Foundation, the number of holders of PhD in biological sciences who end up in tenure track has consistently dropped from over 50% in 1973 to less than 20% in 2006. They continue their studies or carry out research and further increase expertise in a specialist subject, including integrating a team and acquiring novel skills and research methods. Postdoctoral research is often considered essential while advancing the scholarly mission of the host institution; it is expected to produce relevant publications in peer-reviewed academic journals or conferences. In some countries, postdoctoral research may lead to further for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institute Of Mental Health
The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research. NIMH is the largest research organization in the world specializing in mental illness. Shelli Avenevoli is the current acting director of NIMH. The institute was first authorized by the U.S. government in 1946, when then President Harry Truman signed into law the National Mental Health Act, although the institute was not formally established until 1949. NIMH is a $1.5 billion enterprise, supporting research on mental health through grants to investigators at institutions and organizations throughout the United States and through its own internal (intramural) research effort. The mission statement, mission of NIMH is "to transform the understan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quebec
Quebec is Canada's List of Canadian provinces and territories by area, largest province by area. Located in Central Canada, the province shares borders with the provinces of Ontario to the west, Newfoundland and Labrador to the northeast, New Brunswick to the southeast and a coastal border with the territory of Nunavut. In the south, it shares a border with the United States. Between 1534 and 1763, what is now Quebec was the List of French possessions and colonies, French colony of ''Canada (New France), Canada'' and was the most developed colony in New France. Following the Seven Years' War, ''Canada'' became a Territorial evolution of the British Empire#List of territories that were once a part of the British Empire, British colony, first as the Province of Quebec (1763–1791), Province of Quebec (1763–1791), then Lower Canada (1791–1841), and lastly part of the Province of Canada (1841–1867) as a result of the Lower Canada Rebellion. It was Canadian Confederation, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Montreal
Montreal is the List of towns in Quebec, largest city in the Provinces and territories of Canada, province of Quebec, the List of the largest municipalities in Canada by population, second-largest in Canada, and the List of North American cities by population, ninth-largest in North America. It was founded in 1642 as ''Fort Ville-Marie, Ville-Marie'', or "City of Mary", and is now named after Mount Royal, the triple-peaked mountain around which the early settlement was built. The city is centred on the Island of Montreal and a few, much smaller, peripheral islands, the largest of which is Île Bizard. The city is east of the national capital, Ottawa, and southwest of the provincial capital, Quebec City. the city had a population of 1,762,949, and a Census geographic units of Canada#Census metropolitan areas, metropolitan population of 4,291,732, making it the List of census metropolitan areas and agglomerations in Canada, second-largest metropolitan area in Canada. French l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Regis High School (New York City)
Regis High School is a private, all-male, Jesuit secondary school located on the Upper East Side of Manhattan in New York City. History Founding Regis High School was founded in 1914, through the financial bequest of a single (originally anonymous) benefactress, Julia M. Grant, the widow of New York City mayor Hugh J. Grant. She stipulated that her gift be used to build a Jesuit high school providing a free education for Catholic boys with special consideration given to those who could not otherwise afford a Catholic education. The school continues that policy and does not charge tuition. Following the death of her husband in 1910, Julia Grant met with David W. Hearn, S.J. and, with a stipulation of strict anonymity, gave him an envelope with the money needed to start a school to educate Catholic boys. From its opening in 1914 until the late 1960s, Regis was regarded by Julia Grant and her children as their private charity. Only in the late 1960s did they reluctantly agree t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Edvard Moser
Edvard Ingjald Moser () is a Norwegian psychologist and neuroscientist, who is a professor at the Norwegian University of Science and Technology (NTNU) in Trondheim. He shared the Nobel Prize in Physiology or Medicine in 2014 with long-term collaborator and then-wife May-Britt Moser, and previous mentor John O'Keefe for their work identifying the brain's positioning system. The two main components of the brain's GPS are grid cells and place cells, a specialized type of neuron that respond to specific locations in space. Together with May-Britt Moser he established the Moser research environment. In 1996 he was appointed as associate professor in biological psychology at the Department of Psychology at the Norwegian University of Science and Technology (NTNU); he was promoted to professor of neuroscience in 1998. In 2002, his research group was given the status of a separate "centre of excellence". Edvard Moser has led a succession of research groups and centres, collectivel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
May-Britt Moser
May-Britt Moser (born 1963) is a Norwegian psychologist and neuroscientist, who is a Professor of Psychology and Neuroscience at the Norwegian University of Science and Technology (NTNU). She and her former husband, Edvard Moser, shared half of the 2014 Nobel Prize in Physiology or Medicine, awarded for work concerning the grid cells in the entorhinal cortex, as well as several additional space-representing cell types in the same circuit that make up the positioning system in the brain. Together with Edvard Moser she established the Moser research environment at NTNU, which they lead. Since 2012 she has headed the Centre for Neural Computation. Moser received her education as a psychologist at the Department of Psychology, University of Oslo and obtained a PhD in neurophysiology at the Faculty of Medicine in 1995; in 1996 she was appointed as associate professor in biological psychology at the Department of Psychology at the Norwegian University of Science and Technolog ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phase Precession
Phase precession is a neurophysiological process in which the time of firing of action potentials by individual neurons occurs progressively earlier in relation to the phase of the local field potential oscillation with each successive cycle. In place cells, a type of neuron found in the hippocampal region of the brain, phase precession is believed to play a major role in the neural coding of information. John O'Keefe, who later shared the 2014 Nobel Prize in Physiology or Medicine for his discovery that place cells help form a "map" of the body's position in space, co-discovered phase precession with Michael Recce in 1993. Place cells Pyramidal cells in the hippocampus called place cells play a significant role in self-location during movement over short distances. As a rat moves along a path, individual place cells fire action potentials at an increased rate at particular positions along the path, termed "place fields". Each place cell's maximum firing ratewith action pot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Theta Wave
Theta waves generate the theta rhythm, a neural oscillation in the brain that underlies various aspects of cognition and behavior, including learning, memory, and spatial navigation in many animals. It can be recorded using various electrophysiological methods, such as electroencephalogram (EEG), recorded either from inside the brain or from electrodes attached to the scalp. At least two types of theta rhythm have been described. The hippocampal theta rhythm is a strong oscillation that can be observed in the hippocampus and other brain structures in numerous species of mammals including rodents, rabbits, dogs, cats, and marsupials. ''"Cortical theta rhythms"'' are low-frequency components of scalp EEG, usually recorded from humans. Theta rhythms can be quantified using quantitative electroencephalography (qEEG) using freely available toolboxes, such as, EEGLAB or the Neurophysiological Biomarker Toolbox (NBT). In rats, theta wave rhythmicity is easily observed in the hipp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
