Internal Granular Layer (cerebral Cortex)
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Internal Granular Layer (cerebral Cortex)
The internal granular layer of the cortex, also commonly referred to as the granular layer of the cortex, is the layer IV in the subdivision of the mammalian cortex into 6 layers. The adjective internal is used in opposition to the external granular layer of the cortex, the term granular refers to the granule cells found here. This layer receives the afferent connections from the thalamus and from other cortical regions and sends connections to the other layers. The line of Gennari The line of Gennari (also called the "band" or "stria" of Gennari) is a band of myelinated axons that runs parallel to the surface of the cerebral cortex on the banks of the calcarine fissure in the occipital lobe. This formation is visible to the ... (occipital stripe) is also present in this layer. Cerebral cortex {{neuroanatomy-stub ...
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Cerebral Cortex
The cerebral cortex, also known as the cerebral mantle, is the outer layer of neural tissue of the cerebrum of the brain in humans and other mammals. The cerebral cortex mostly consists of the six-layered neocortex, with just 10% consisting of allocortex. It is separated into two cortices, by the longitudinal fissure that divides the cerebrum into the left and right cerebral hemispheres. The two hemispheres are joined beneath the cortex by the corpus callosum. The cerebral cortex is the largest site of neural integration in the central nervous system. It plays a key role in attention, perception, awareness, thought, memory, language, and consciousness. The cerebral cortex is part of the brain responsible for cognition. In most mammals, apart from small mammals that have small brains, the cerebral cortex is folded, providing a greater surface area in the confined volume of the cranium. Apart from minimising brain and cranial volume, cortical folding is crucial for the brain ...
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External Granular Layer (cerebral Cortex)
The external granular layer of the cerebral cortex is commonly known as layer II. It is different from the internal granular layer of the cerebral cortex (commonly known as layer IV). Layer II is often grouped together with layer III and referred to as layer II/III. Layers I, II, and III are together referred to as the supragranular layers, because they are above layer IV. Brodmann has this to say about layer II: "The most inconstant or variable layers are Meynert's two so-called granular layers, layers II and IV of the basic pattern (the outer and inner granular layers). They alter their original cytoarchitectonic features so extensively during ontogeny that it is often only possible to correlate their mature structure with their primitive tectogenetic form by following the whole developmental sequence. Extreme variation, such as the disappearance or doubling of layers that we have already discussed, occur particularly in them, and their specific organisation also varies w ...
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Granule Cell
A granule is a large particle or grain. It can refer to: * Granule (cell biology), any of several submicroscopic structures, some with explicable origins, others noted only as cell type-specific features of unknown function ** Azurophilic granule, a structure characteristic of the azurophil eukaryotic cell type ** Chromaffin granule, a structure characteristic of the chromophil eukaryotic cell type. * Astrophysics and geology: ** Granule (solar physics), a visible structure in the photosphere of the Sun arising from activity in the Sun's convective zone ** Martian spherules, spherical granules of material found on the surface of the planet Mars ** Granule (geology), a specified particle size of 2–4 millimetres (-1 to -2 on the φ scale) * Granule, in pharmaceutical terms, small particles gathered into a larger, permanent aggregate in which the original particles can still be identified * Granule (Oracle DBMS), a unit of contiguously allocated virtual memory * Granular synthesis ...
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Afferent Nerve Fiber
Afferent nerve fibers are the axons (nerve fibers) carried by a sensory nerve that relay sensory information from sensory receptors to regions of the brain. Afferent projections ''arrive'' at a particular brain region. Efferent nerve fibers are carried by efferent nerves and ''exit'' a region to act on muscles and glands. In the peripheral nervous system afferent and efferent nerve fibers are part of the somatic nervous system and arise from outside of the spinal cord. Sensory nerves carry the afferent fibers to enter into the spinal cord, and motor nerves carry the efferent fibers out of the spinal cord to act on skeletal muscles. In the central nervous system non-motor efferents are carried in efferent nerves to act on glands. Structure Afferent neurons are pseudounipolar neurons that have a single process leaving the cell body dividing into two branches: the long one towards the sensory organ, and the short one toward the central nervous system (e.g. spinal cord). The ...
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Thalamus
The thalamus (from Greek θάλαμος, "chamber") is a large mass of gray matter located in the dorsal part of the diencephalon (a division of the forebrain). Nerve fibers project out of the thalamus to the cerebral cortex in all directions, allowing hub-like exchanges of information. It has several functions, such as the relaying of sensory signals, including motor signals to the cerebral cortex and the regulation of consciousness, sleep, and alertness. Anatomically, it is a paramedian symmetrical structure of two halves (left and right), within the vertebrate brain, situated between the cerebral cortex and the midbrain. It forms during embryonic development as the main product of the diencephalon, as first recognized by the Swiss embryologist and anatomist Wilhelm His Sr. in 1893. Anatomy The thalamus is a paired structure of gray matter located in the forebrain which is superior to the midbrain, near the center of the brain, with nerve fibers projecting out to the ...
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Line Of Gennari
The line of Gennari (also called the "band" or "stria" of Gennari) is a band of myelinated axons that runs parallel to the surface of the cerebral cortex on the banks of the calcarine fissure in the occipital lobe. This formation is visible to the naked eye as a white strip running through the cortical grey matter, and is the reason the V1 in primates is also referred to as the "striate cortex." The line of Gennari is due to dense axonal input from the thalamus to layer IV of visual cortex. It is the name given to the enlarged external band of Baillarger. The structure is named for its discoverer, Francesco Gennari, who first observed it in 1776 as a medical student at the University of Parma. He described it in a book which he published six years later. Although non-primate species have areas that are designated primary visual cortex, some (if not all) lack a stria of Gennari.Zilles and Wree. ''Isocortex'' in Paxinos (Ed.) ''The Rat Nervous System'', 1985. See also * Cerebral cort ...
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