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Institute Of Molecular Biology
The Institute of Molecular Biology (IMB) is a modern research centre on the campus of the Johannes Gutenberg University of Mainz, University in Mainz, Germany. It is funded by the Boehringer Ingelheim Foundation and the state of Rheinland Palatinate. The scientists at IMB primarily conduct basic science in developmental biology, epigenetics, genome stability and related areas. History * In early 2009 the Boehringer Ingelheim Foundation decided to fund a new centre of excellence in the life sciences. * The federal state of Rhineland-Palatinate financed the construction of a new building, starting in December 2009 on the campus of the University of Mainz. * In May 2010 developmental biologist Christof Niehrs (formerly at the German Cancer Research Center, DKFZ) was appointed as the institute's founding director. The institute was then named "Institute of Molecular Biology" and the institute's research focus on developmental biology, epigenetics, and DNA repair was set. * The major ...
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Developmental Biology
Developmental biology is the study of the process by which animals and plants grow and develop. Developmental biology also encompasses the biology of Regeneration (biology), regeneration, asexual reproduction, metamorphosis, and the growth and differentiation of stem cells in the adult organism. Perspectives The main processes involved in the embryogenesis, embryonic development of animals are: tissue patterning (via regional specification and patterned cellular differentiation, cell differentiation); tissue growth; and tissue morphogenesis. * Regional specification refers to the processes that create the spatial patterns in a ball or sheet of initially similar cells. This generally involves the action of cytoplasmic determinants, located within parts of the fertilized egg, and of inductive signals emitted from signaling centers in the embryo. The early stages of regional specification do not generate functional differentiated cells, but cell populations committed to developing ...
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Proteome
The proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time. It is the set of expressed proteins in a given type of cell or organism, at a given time, under defined conditions. Proteomics is the study of the proteome. Types of proteomes While proteome generally refers to the proteome of an organism, multicellular organisms may have very different proteomes in different cells, hence it is important to distinguish proteomes in cells and organisms. A cellular proteome is the collection of proteins found in a particular cell type under a particular set of environmental conditions such as exposure to hormone stimulation. It can also be useful to consider an organism's complete proteome, which can be conceptualized as the complete set of proteins from all of the various cellular proteomes. This is very roughly the protein equivalent of the genome. The term ''proteome'' has also been used to refer to the collectio ...
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Whitehead Institute
Whitehead Institute for Biomedical Research is a non-profit research institute located in Cambridge, Massachusetts, United States that is dedicated to improving human health through basic biomedical research. It was founded as a fiscally independent entity from the Massachusetts Institute of Technology (MIT), where its 18 members all hold faculty appointments in the MIT Department of Biology or the MIT Department of Bioengineering. Two members (Rudolf Jaenisch, 2010, and Robert Weinberg, 1997) are National Medal of Science recipients; ten have been elected to the National Academy of Sciences; and four have been elected to the National Academy of Medicine; six are Howard Hughes Medical Institute Investigators. In September 2019, Ruth Lehmann was announced as the new director of the Whitehead Institute for Biomedical Research, commencing July 2020 and succeeding David Page. History Whitehead Institute was founded in 1982 by industrialist and philanthropist Edwin C. “Jack” ...
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University Of Copenhagen
The University of Copenhagen ( da, Københavns Universitet, KU) is a prestigious public university, public research university in Copenhagen, Copenhagen, Denmark. Founded in 1479, the University of Copenhagen is the second-oldest university in Scandinavia after Uppsala University, and ranks as one of the top universities in the Nordic countries, Europe and the world. Its establishment sanctioned by Pope Sixtus IV, the University of Copenhagen was founded by Christian I of Denmark as a Catholic teaching institution with a predominantly Theology, theological focus. In 1537, it was re-established by King Christian III as part of the Lutheran Reformation. Up until the 18th century, the university was primarily concerned with educating clergymen. Through various reforms in the 18th and 19th century, the University of Copenhagen was transformed into a modern, Secularism, secular university, with science and the humanities replacing theology as the main subjects studied and taught. Th ...
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University Of Utah
The University of Utah (U of U, UofU, or simply The U) is a public research university in Salt Lake City, Utah. It is the flagship institution of the Utah System of Higher Education. The university was established in 1850 as the University of Deseret () by the General Assembly of the provisional State of Deseret, making it Utah's oldest institution of higher education. It received its current name in 1892, four years before Utah attained statehood, and moved to its current location in 1900. As of Fall 2019, there were 24,485 undergraduate students and 8,333 graduate students, for an enrollment total of 32,818, making it the second largest public university in the state after Utah Valley University. Graduate studies include the S.J. Quinney College of Law and the School of Medicine, Utah's first medical school. It is a member of the Association of American Universities (AAU) and is classified among "R1: Doctoral Universities – Very high research activity". According to the ...
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Huntsman Cancer Institute
Huntsman Cancer Institute (HCI) is an NCI-designated cancer research facility and hospital located on the campus of the University of Utah in Salt Lake City, Utah. It is the only National Cancer Institute-designated Comprehensive Cancer Center in the Intermountain West. Overview Huntsman Cancer Institute was founded with a pledge of $100 million of personal wealth from Jon Huntsman Sr., a philanthropist and businessman. To date, Huntsman has donated more than $250 million of his own money since Huntsman Cancer Institute was established. Mary Beckerle is HCI's chief executive officer and director. In November 2013, Huntsman donated an additional $50 million for the construction of a new research building dedicated to researching children's cancer and cancers that run in families. The Primary Children's and Families' Research Center opened in 2017. In 2015, the National Cancer Institute awarded HCI Comprehensive Cancer Center status. Research Scientists at the in ...
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Ludwig Maximilian University Of Munich
The Ludwig Maximilian University of Munich (simply University of Munich or LMU; german: Ludwig-Maximilians-Universität München) is a public research university in Munich, Germany. It is Germany's sixth-oldest university in continuous operation. Originally established in Ingolstadt in 1472 by Duke Ludwig IX of Bavaria-Landshut, the university was moved in 1800 to Landshut by King Maximilian I of Bavaria when the city was threatened by the French, before being relocated to its present-day location in Munich in 1826 by King Ludwig I of Bavaria. In 1802, the university was officially named Ludwig-Maximilians-Universität by King Maximilian I of Bavaria in honor of himself and Ludwig IX. LMU is currently the second-largest university in Germany in terms of student population; in the 2018/19 winter semester, the university had a total of 51,606 matriculated students. Of these, 9,424 were freshmen while international students totalled 8,875 or approximately 17% of the student pop ...
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Immunology
Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there is a difference of human immunology and comparative immunology in veterinary medicine and animal biosciences. Immunology measures, uses charts and differentiate in context in medicine the studies of immunity on cell and molecular level, and the immune system as part of the physiological level as its functioning is of major importance. In the different states of both health, occurring symptoms and diseases; the functioning of the immune system and immunological responses such as autoimmune diseases, allergic hypersensitivities, or in some cases malfunctioning of immune system as for example in immunological disorders or in immune deficiency, and the specific transplant rejection) Immunology has applications in numerous disciplines of ...
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Telomere
A telomere (; ) is a region of repetitive nucleotide sequences associated with specialized proteins at the ends of linear chromosomes. Although there are different architectures, telomeres, in a broad sense, are a widespread genetic feature most commonly found in eukaryotes. In most, if not all species possessing them, they protect the terminal regions of chromosomal DNA from progressive degradation and ensure the integrity of linear chromosomes by preventing DNA repair systems from mistaking the very ends of the DNA strand for a double-strand break. Discovery In the early 1970s, Soviet theorist Alexei Olovnikov first recognized that chromosomes could not completely replicate their ends; this is known as the "end replication problem". Building on this, and accommodating Leonard Hayflick's idea of limited somatic cell division, Olovnikov suggested that DNA sequences are lost every time a cell replicates until the loss reaches a critical level, at which point cell division end ...
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German Research Foundation
The German Research Foundation (german: Deutsche Forschungsgemeinschaft ; DFG ) is a German research funding organization, which functions as a self-governing institution for the promotion of science and research in the Federal Republic of Germany. In 2019, the DFG had a funding budget of €3.3 billion. Function The DFG supports research in science, engineering, and the humanities through a variety of grant programmes, research prizes, and by funding infrastructure. The self-governed organization is based in Bonn and financed by the German states and the federal government of Germany. As of 2017, the organization consists of approximately 100 research universities and other research institutions. The DFG endows various research prizes, including the Leibniz Prize. The Polish-German science award Copernicus Award, Copernicus is offered jointly with the Foundation for Polish Science. According to a 2017 article in ''The Guardian'', the DFG has announced it will publish its re ...
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Chronobiology
Chronobiology is a field of biology that examines timing processes, including periodic (cyclic) phenomena in living organisms, such as their adaptation to solar- and lunar-related rhythms. These cycles are known as biological rhythms. Chronobiology comes from the ancient Greek χρόνος (''chrónos'', meaning "time"), and biology, which pertains to the study, or science, of life. The related terms ''chronomics'' and ''chronome'' have been used in some cases to describe either the molecular mechanisms involved in chronobiological phenomena or the more quantitative aspects of chronobiology, particularly where comparison of cycles between organisms is required. Chronobiological studies include but are not limited to comparative anatomy, physiology, genetics, molecular biology and behavior of organisms related to their biological rhythms. Other aspects include epigenetics, development, reproduction, ecology and evolution. The subject Chronobiology studies variations of the ...
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Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ...
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