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House's Head
"House's Head" is the fifteenth episode of the fourth season of ''House'' and the eighty-fifth episode overall. It was the first part of the two-part season four finale, the second part being " Wilson's Heart". Co-written by several ''House'' producers and directed by Greg Yaitanes, "House's Head" premiered on May 12, 2008, on Fox. The episode revolves around Dr. Gregory House (Hugh Laurie), who, after being involved in a bus accident, vaguely remembers seeing someone who is "going to die". House tries to trace back his steps throughout the episode to find out the identity of this person. A woman (Ivana Miličević), who claims to be "the answer", guides House through hallucinations about the crash. The episode eventually ends in a cliffhanger. 14.84 million American viewers watched the broadcasting of "House's Head", making ''House'' the ninth most-watched program of the week. The episode was submitted for five Primetime Emmy Awards, from which two nominations followed. Greg Yai ...
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House (TV Series)
''House'' (also known as ''House, M.D.'') is an American medical drama television series created by David Shore for Fox Broadcasting Company, Fox. It ran for eight seasons from November 16, 2004, to May 21, 2012. It features the life of Dr. Gregory House (Hugh Laurie), an unconventional, Misanthropy, misanthropic, cynical medical genius who, despite his dependence on pain medication, successfully leads a team of Medical diagnosis, diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital (PPTH) in New Jersey. House often clashes with his fellow physicians, including his own diagnostic team, because many of his hypotheses about patients' illnesses are based on subtle or controversial insights, and his flouting of hospital rules and procedures frequently leads him into conflict with his boss, hospital administrator and Dean of Medicine Dr. Lisa Cuddy (Lisa Edelstein). House's only true friend is Dr. James Wilson (House), James Wilson (Robert Sean Leonard), head of ...
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AMC (TV Channel)
AMC (an abbreviation of the channel's original name, American Movie Classics) is an American basic cable television channel that is the flagship property of AMC Networks. Launched in late 1984, the channel aired classic films prior to the 1970s, similar to Turner Classic Movies, the channel's former rival, until 2002, when AMC retired the American Movie Classics name as a result of a Channel drift, major shift in List of programs broadcast by AMC, its programming, and today airs original shows that are mainly dramas and documentaries, while airing theatrically released films, and acquired television programming. As of December 2024, AMC was available in approximately 60 million U.S. pay-TV households. This marks a decline from 65.1 million households in December 2023 and 94.8 million in July 2015, reflecting the broader trend of cord-cutting and the shift toward streaming platforms. History 1984–2002: Focus on classic films American Movie Classics, as AMC was originally kn ...
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Cardiopulmonary Resuscitation
Cardiopulmonary resuscitation (CPR) is an emergency procedure used during Cardiac arrest, cardiac or Respiratory arrest, respiratory arrest that involves chest compressions, often combined with artificial ventilation, to preserve brain function and maintain circulation until spontaneous breathing and heartbeat can be restored. It is indication (medicine), recommended for those who are unresponsive with no breathing or abnormal breathing, for example, agonal respirations. CPR involves chest compressions for adults between and deep and at a rate of at least 100 to 120 per minute. The rescuer may also provide artificial ventilation by either exhaling air into the subject's mouth or nose (mouth-to-mouth resuscitation) or using a device that pushes air into the subject's lungs (mechanical ventilation). Current recommendations emphasize early and high-quality chest compressions over artificial ventilation; a simplified CPR method involving only chest compressions is recommended for ...
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Amber
Amber is fossilized tree resin. Examples of it have been appreciated for its color and natural beauty since the Neolithic times, and worked as a gemstone since antiquity."Amber" (2004). In Maxine N. Lurie and Marc Mappen (eds.) ''Encyclopedia of New Jersey'', Rutgers University Press, . Amber is used in jewelry and as a healing agent in Traditional medicine, folk medicine. There are five classes of amber, defined on the basis of their chemical constituents. Because it originates as a soft, sticky tree resin, amber sometimes contains animal and plant material as Inclusion (mineral), inclusions. Amber occurring in coal seams is also called resinite, and the term ''ambrite'' is applied to that found specifically within New Zealand coal seams. Etymology The English word ''amber'' derives from Arabic from Middle Persian 𐭠𐭭𐭡𐭫 (''ʾnbl'' /⁠ambar⁠/, “ambergris”) via Medieval Latin, Middle Latin ''ambar'' and Middle French ''ambre''. The word referred to what is n ...
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Physostigmine
Physostigmine (also known as eserine from ''éséré'', the West African name for the Calabar bean) is a highly toxic parasympathomimetic alkaloid, specifically, a reversible cholinesterase inhibitor. It occurs naturally in the Calabar bean and the fruit of the Manchineel tree. The chemical was synthesized for the first time in 1935 by Percy Lavon Julian and Josef Pikl. It is available in the U.S. under the trade names Antilirium and Isopto Eserine, and as eserine salicylate and eserine sulfate. Today, physostigmine is most commonly used for its medicinal value. However, before its discovery by Robert Christison, Sir Robert Christison in 1846, it was much more prevalent as an ordeal poison. The positive medical applications of the drug were first suggested in the gold medal-winning final thesis of Thomas Richard Fraser at the University of Edinburgh in 1862. Medical uses Physostigmine, an acetylcholinesterase inhibitor, can be used to treat glaucoma and delayed gastric emptyin ...
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Pulmonary Embolism
Pulmonary embolism (PE) is a blockage of an pulmonary artery, artery in the lungs by a substance that has moved from elsewhere in the body through the bloodstream (embolism). Symptoms of a PE may include dyspnea, shortness of breath, chest pain particularly upon breathing in, and coughing up blood. Symptoms of a deep vein thrombosis, blood clot in the leg may also be present, such as a erythema, red, warm, swollen, and painful leg. Signs of a PE include low blood oxygen saturation, oxygen levels, tachypnea, rapid breathing, tachycardia, rapid heart rate, and sometimes a mild fever. Severe cases can lead to Syncope (medicine), passing out, shock (circulatory), abnormally low blood pressure, obstructive shock, and cardiac arrest, sudden death. PE usually results from a blood clot in the leg that travels to the lung. The risk of blood clots is increased by advanced age, cancer, prolonged bed rest and immobilization, smoking, stroke, long-haul travel over 4 hours, certain genetics, ...
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Thrombus
A thrombus ( thrombi) is a solid or semisolid aggregate from constituents of the blood (platelets, fibrin, red blood cells, white blood cells) within the circulatory system during life. A blood clot is the final product of the blood coagulation step in hemostasis in or out of the circulatory system. There are two components to a thrombus: aggregated platelets and red blood cells that form a plug, and a mesh of cross-linked fibrin protein. The substance making up a thrombus is sometimes called cruor. A thrombus is a healthy response to injury intended to stop and prevent further bleeding, but can be harmful in thrombosis, when a clot obstructs blood flow through a healthy blood vessel in the circulatory system. In the microcirculation consisting of the very small and smallest blood vessels the capillaries, tiny thrombi known as microclots can obstruct the flow of blood in the capillaries. This can cause a number of problems particularly affecting the pulmonary alveolus, alveoli ...
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Intubation
Intubation (sometimes entubation) is a medical procedure involving the insertion of a tube into the body. Most commonly, intubation refers to tracheal intubation, a procedure during which an endotracheal tube is inserted into the trachea to support patient ventilation. Other examples of intubation include balloon tamponade using a Sengstaken–Blakemore tube (a tube into the gastrointestinal tract), urinary catheterization, and nasogastric intubation using a feeding tube. Types of Intubation and Their Indications Tracheal Intubation Tracheal intubation is a procedure involving the placement of an endotracheal tube into a patient’s windpipe, also known as the trachea. This procedure may be done to treat either emergent or non-emergent conditions. Examples of emergent conditions include airway compromise, respiratory failure, allergic reactions, and trauma. An example of a non-emergent condition where tracheal intubation is performed includes surgery, during which an indi ...
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Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become more prevalent as the disease progresses. The motor symptoms are collectively called parkinsonism and include tremors, bradykinesia, spasticity, rigidity as well as postural instability (i.e., difficulty maintaining balance). Non-motor symptoms develop later in the disease and include behavior change (individual), behavioral changes or mental disorder, neuropsychiatric problems such as sleep abnormalities, psychosis, anosmia, and mood swings. Most Parkinson's disease cases are idiopathic disease, idiopathic, though contributing factors have been identified. Pathophysiology involves progressive nerve cell death, degeneration of nerve cells in the substantia nigra, a midbrain region that provides dopamine to the basal ganglia, a system invo ...
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Lisa Cuddy
Lisa Cuddy, M.D., is a fictional character on the medical drama ''House''. She is portrayed by Lisa Edelstein. Cuddy was the dean of medicine of the fictional Princeton-Plainsboro Teaching Hospital in New Jersey. Cuddy quit her job after the events of season seven's finale " Moving On". Storylines Cuddy's job title in ''House'' is Dean of Medicine and Hospital Administrator. She is Jewish, and has a mother and one sister; her father is dead. She began dreaming of becoming a doctor when she was 12, graduated from medical school at age 25 as second best in her class, and became the first female and second youngest Dean of Medicine at the age of 32 (she was actually 29 but she added three years to her age in order to seem more mature to the Selection Committee). Cuddy attended the University of Michigan, where she first met Gregory House (Hugh Laurie), and with whom she shared a one-night stand. After hiring House to run the hospital's Diagnostics Department, Cuddy began setting asid ...
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Retrograde Amnesia
In neurology, retrograde amnesia (RA) is the inability to access memories or information from before an injury or disease occurred. RA differs from a similar condition called anterograde amnesia (AA), which is the inability to form new memories following injury or disease onset. Although an individual can have both RA and AA at the same time, RA can also occur on its own; this 'pure' form of RA can be further divided into three types: focal, isolated, and pure RA. RA negatively affects an individual's Episodic memory, episodic, Autobiographical memory, autobiographical, and declarative memory, but they can still form new memories because RA leaves procedural memory intact. Depending on its severity, RA can result in either temporally graded or more permanent memory loss. However, memory loss usually follows Ribot's law, which states that individuals are more likely to lose recent memories than older memories. Diagnosing RA generally requires using an Autobiographical Memory Intervi ...
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Post-traumatic Amnesia
Post-traumatic amnesia (PTA) is a state of mental confusion, confusion that occurs immediately following a traumatic brain injury (TBI) in which the injured person is Orientation (mental), disoriented and unable to remember events that occur after the physical injury, injury. The person may be unable to state their name, where they are, and what time it is. When continuous memory returns, PTA is considered to have resolved. While PTA lasts, new events cannot be stored in the memory. About a third of patients with mild head injury are reported to have "islands of memory", in which the patient can recall only some events. During PTA, the patient's consciousness is "clouded". Because PTA involves confusion in addition to the memory loss typical of amnesia, the term ''"post-traumatic confusional state"'' has been proposed as an alternative. There are two types of amnesia: retrograde amnesia (loss of memories that were formed shortly before the injury) and anterograde amnesia (pr ...
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