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Ghon's Complex
Ghon's complex is a lesion seen in the lung that is caused by tuberculosis. The lesions consist of a Ghon focus along with pulmonary lymphadenopathy within a nearby pulmonary lymph node. A Ghon's complex retains viable bacteria, making them sources of long-term infection, which may reactivate and trigger secondary tuberculosis later in life. In countries where cow milk infected with ''Mycobacterium bovis'' has been eliminated (due to culling of infected cows and pasteurization), primary tuberculosis is usually caused by ''Mycobacterium tuberculosis'' and almost always begins in the lungs. Typically, the inhaled bacilli implant in the distal airspaces of the lower part of the upper lobe or the upper part of the lower lobe, usually close to the pleura. As sensitization develops, a 1 to 1.5 cm area of gray-white inflammation with consolidation emerges, known as the Ghon focus. In most cases, the center of this focus undergoes caseous necrosis. Tubercle bacilli, either free or wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chest X-ray Of Ghon's Complex Of Active Tuberculosis
The thorax (: thoraces or thoraxes) or chest is a part of the anatomy of mammals and other tetrapod animals located between the neck and the abdomen. In insects, crustaceans, and the extinct trilobites, the thorax is one of the three main Tagma (biology), divisions of the body, each in turn composed of multiple segments. The human thorax includes the thoracic cavity and the thoracic wall. It contains organs including the heart, lungs, and thymus gland, as well as muscles and various other internal structures. The chest may be affected by many diseases, of which the most common symptom is chest pain. Etymology The word thorax comes from the Ancient Greek, Greek θώραξ ''thṓrax'' "breastplate, cuirass, corslet" via . Humans Structure In humans and other Hominidae, hominids, the thorax is the chest region of the body between the neck and the abdomen, along with its internal Organ (anatomy), organs and other contents. It is mostly protected and supported by the rib cage, v ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caseous Necrosis
Caseous necrosis or caseous degeneration () is a unique form of cell death in which the tissue maintains a cheese-like appearance.Robbins and Cotran: Pathologic Basis of Disease, 8th Ed. 2010. Pg. 16 Unlike with coagulative necrosis, tissue structure is destroyed. Caseous necrosis is enclosed within a granuloma. Caseous necrosis is most notably associated with tuberculoma. The dead tissue appears as a soft and white proteinaceous dead cell mass. The term ''caseous'' means 'pertaining or related to cheese', and comes from the Latin word 'cheese'. Histology In caseous necrosis no histological architecture is preserved (unlike with coagulative necrosis). On microscopic examination with H&E staining, the area is acellular, characterised by amorphous, roughly granular eosinophilic debris of now dead cells, also containing interspearsed haematoxyphilic remnants of cell nucleus contents. This caseus necrotic center is enclosed within a granuloma. Causes Frequently caseous necrosis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gross Pathology
Gross pathology refers to macroscopic manifestations of disease in organ (anatomy), organs, Tissue (biology), tissues, and body cavity, body cavities. The term is commonly used by anatomical pathology, anatomical pathologists to refer to diagnostically useful findings made during the gross examination portion of surgical specimen processing or an autopsy. In the intricate process of anatomical pathology, the grossing stage plays a pivotal role. It is vital to systematically explain the gross appearance of a pathological state, for example, a malignant tumor, noting the site, size, shape, consistency, presence of a capsule and appearance on cut section whether well circumscribed or diffusely infiltrating, homogeneous or variegated, cystic, necrotic, hemorrhagic areas, as well as papillary projections. Therefore, upon receipt of a specimen, pathologists meticulously document its characteristics. They note the specimen's dimensions, hue, texture, and any distinctive features that st ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Who Named It
''Whonamedit?'' is an online English-language dictionary of medical eponyms and the people associated with their identification. Though it is a dictionary, many eponyms and persons are presented in extensive articles with comprehensive bibliographies. The dictionary is hosted in Norway Norway, officially the Kingdom of Norway, is a Nordic countries, Nordic country located on the Scandinavian Peninsula in Northern Europe. The remote Arctic island of Jan Mayen and the archipelago of Svalbard also form part of the Kingdom of ... and was developed by medical historian Ole Daniel Enersen. References External links * Medical websites Medical dictionaries Eponyms in medicine {{online-dict-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karl Ernst Ranke
Karl Ernst Ranke (29 January 1870 in Munich – 9 November 1926 in Munich) was a German internist, pediatrician and pulmonologist known for his research of tuberculosis. He was the son of anthropologist Johannes Ranke (1836–1916). In 1896 he received his medical doctorate from the University of Munich, then spent the following year as an assistant to his uncle, Heinrich von Ranke (1830–1909), at the pediatric clinic in Munich. Afterwards, he was in charge of an anthropological research expedition to Brazil. Following his return to Germany, he spent two additional years as an assistant in the pediatric clinic, then relocated to Arosa, Switzerland, where he worked as a doctor in a tuberculosis sanatorium.Karl Ernst Ranke at |
Anton Ghon
Anton Ghon (1 January 1866 – 23 April 1936) was an Austrian pathologist and bacteriologist. He is best known for his research on tuberculosis ( Ghon's complex). Biography Ghon was born on January 1, 1866, in Villach. From 1884 to 1890, Ghon studied medicine at the university in Graz. In 1890 he volunteered at the dermatologic clinic in Vienna. In 1892, he became an aspirant to the pathologic-anatomic division at ''Krankenanstalt Rudolfstiftung'' (Rudolf Foundation). In 1893, he worked as demonstrator to the chair of pathological histology and bacteriology and as of 1894 as assistant of Anton Weichselbaum (1845–1920) at the pathological-anatomical institute at the University of Vienna. Anton Ghon travelled to Bombay in 1897 as a member of the Austrian delegation researching the bubonic plague. For their findings on aetiology, anatomical pathology and epidemiology, he and his colleagues were nominated for the Nobel Prize in 1901. Ghon completed his habilitation in 1899 in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calcification
Calcification is the accumulation of calcium salts in a body tissue. It normally occurs in the formation of bone, but calcium can be deposited abnormally in soft tissue,Miller, J. D. Cardiovascular calcification: Orbicular origins. ''Nature Materials'' 12, 476-478 (2013). causing it to harden. Calcifications may be classified on whether there is mineral balance or not, and the location of the calcification. Calcification may also refer to the processes of normal mineral deposition in biological systems, such as the formation of stromatolites or mollusc shells (see Biomineralization). Signs and symptoms Calcification can manifest itself in many ways in the body depending on the location. In the pulpal structure of a tooth, calcification often presents asymptomatically, and is diagnosed as an incidental finding during radiographic interpretation. Individual teeth with calcified pulp will typically respond negatively to vitality testing; teeth with calcified pulp often lack ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fibrosis
Fibrosis, also known as fibrotic scarring, is the development of fibrous connective tissue in response to an injury. Fibrosis can be a normal connective tissue deposition or excessive tissue deposition caused by a disease. Repeated injuries, chronic inflammation and repair are susceptible to fibrosis, where an accidental excessive accumulation of extracellular matrix components, such as the collagen, is produced by fibroblasts, leading to the formation of a permanent fibrotic scar. In response to injury, this is called scarring, and if fibrosis arises from a single cell line, this is called a fibroma. Physiologically, fibrosis acts to deposit connective tissue, which can interfere with or totally inhibit the normal architecture and function of the underlying organ or tissue. Fibrosis can be used to describe the pathological state of excess deposition of fibrous tissue, as well as the process of connective tissue deposition in healing. Defined by the pathological accumulation of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hematogenous Dissemination
Bloodstream infections (BSIs) are infections of blood caused by blood-borne pathogens. The detection of microbes in the blood (most commonly accomplished by blood cultures) is always abnormal. A bloodstream infection is different from sepsis, which is characterized by severe inflammatory or immune responses of the host organism to pathogens. Bacteria can enter the bloodstream as a severe complication of infections (like pneumonia or meningitis), during surgery (especially when involving mucous membranes such as the gastrointestinal tract), or due to catheters and other foreign bodies entering the arteries or veins (including during intravenous drug abuse). Transient bacteremia can result after dental procedures or brushing of teeth. Bacteremia can have several important health consequences. Immune responses to the bacteria can cause sepsis and septic shock, which, particularly if severe sepsis and then septic shock occurs, have high mortality rates, especially if not treated qu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nodal Involvement (born 1999), Mexican singer and songwriter
{{Disambig ...
Nodal may refer to: * Nodal, the adjectival form of the noun :wikt:node * Nodal homolog, a protein encoded by the gene NODAL and responsible for left-right asymmetry * Nodal (software), a novel music composition program * Christian Nodal Christian Jesús González Nodal (born January 11, 1999) is a Mexican singer and songwriter. Born and raised in Sonora, he is mainly known for popularizing "mariacheño", a fusion genre between mariachi and Norteño (music), norteño music. Nod ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parenchymal Lung Lesion
upright=1.6, Lung parenchyma showing damage due to large subpleural bullae. Parenchyma () is the bulk of functional substance in an animal organ such as the brain or lungs, or a structure such as a tumour. In zoology, it is the tissue that fills the interior of flatworms. In botany, it is some layers in the cross-section of the leaf. Etymology The term ''parenchyma'' is Neo-Latin from the Ancient Greek word meaning 'visceral flesh', and from meaning 'to pour in' from 'beside' + 'in' + 'to pour'. Originally, Erasistratus and other anatomists used it for certain human tissues. Later, it was also applied to plant tissues by Nehemiah Grew. Structure The parenchyma is the ''functional'' parts of an organ, or of a structure such as a tumour in the body. This is in contrast to the stroma, which refers to the ''structural'' tissue of organs or of structures, namely, the connective tissues. Brain The brain parenchyma refers to the functional tissue in the brain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
