|
Frederick Sanger
Frederick Sanger (; 13 August 1918 – 19 November 2013) was a British biochemist who received the Nobel Prize in Chemistry twice. He won the 1958 Chemistry Prize for determining the amino acid sequence of insulin and numerous other proteins, demonstrating in the process that each had a unique, definite structure; this was a foundational discovery for the central dogma of molecular biology. At the newly constructed Laboratory of Molecular Biology in Cambridge, he developed and subsequently refined the first-ever DNA sequencing technique, which vastly expanded the number of feasible experiments in molecular biology and remains in widespread use today. The breakthrough earned him the 1980 Nobel Prize in Chemistry, which he shared with Walter Gilbert and Paul Berg. He is one of only three people to have won multiple Nobel Prizes in the same category (the others being John Bardeen in physics and Karl Barry Sharpless in chemistry), and one of five persons with two Nobel ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rendcomb
Rendcomb is a village in the Cotswold local authority area of the English county of Gloucestershire. It is about five miles north of Cirencester in the Churn Valley. History Etymology Rendcomb is thought to get its name from the stream running through the small valley or ''coomb'' which lies south of the village. The stream which flows into the Churn, was called ''Hrindan Broc'' in 852 AD, with the modern name of Rendcomb deriving from ''Hrindan'' + ''coomb''. History In 1086 a total of 39 inhabitants of Rendcomb and Eycot was recorded in the Domesday Book as part of Rapsgate Hundred. By 1563, there were 12 households in Rendcomb. The existence of Rendomb Park estate was recorded in 1544, and by the 1670s it consisted of 250 acres. During the Middle Ages, Rendcomb manor was the property of the earls of Gloucester and owned by their knights including the de la Mare family. In 1503, the manor was sold to Edmund Tame of Fairford, son of John Tame. Sir Richard Berkley was th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
William Bate Hardy Prize
The William Bate Hardy Prize is awarded by the Cambridge Philosophical Society. It is awarded once in three years “for the best original memoir, investigation or discovery by a member of the University of Cambridge in connection with Biological Science that may have been published during the three years immediately preceding”. Recipients (''incomplete list-prize awarded at least 22 times by 2014'') *1966 Hugh Huxley (inaugural winner) *1969 Sydney Brenner and Ralph Riley *1976 Frederick Sanger *1978 Richard Henderson *1981 César Milstein *1984 John Gurdon *1987 Michael Berridge *1991 Azim Surani *1993 Martin Evans *1995 Nicholas Barry Davies *1998 Tim Clutton-Brock and Andrew Wyllie (shared) *2001 Michael Neuberger and James Cuthbert Smith (shared) *2004 Andrea Brand and Robin Irvine (shared) *2010 Beverley Glover, Dr Peter Forster and Simon Conway Morrisbr>(shared) *2014 Serena Nik-Zainal See also * List of biology awards This list of biology awards is an inde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
General Practitioner
A general practitioner (GP) is a doctor who is a Consultant (medicine), consultant in general practice. GPs have distinct expertise and experience in providing whole person medical care, whilst managing the complexity, uncertainty and risk associated with the continuous care they provide. GPs work at the heart of their communities, striving to provide comprehensive and equitable care for everyone, taking into account their health care needs, stage of life and background. GPs work in, connect with and lead multidisciplinary teams that care for people and their families, respecting the context in which they live, aiming to ensure all of their physical health and mental health needs are met. They are trained to treat patients to levels of complexity that vary between countries. The term "primary care physician" is used in the United States. A core element in general practice is continuity of care, that bridges episodes of various illnesses over time. Greater continuity with a gen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gloucestershire
Gloucestershire ( , ; abbreviated Glos.) is a Ceremonial counties of England, ceremonial county in South West England. It is bordered by Herefordshire to the north-west, Worcestershire to the north, Warwickshire to the north-east, Oxfordshire to the east, Wiltshire to the south, Bristol and Somerset to the south-west, and the Wales, Welsh county of Monmouthshire to the west. The city of Gloucester is the largest settlement and the county town. The county is predominantly rural, with an area of and a population of 916,212. After Gloucester (118,555) the largest distinct settlements are Cheltenham (115,940), Stroud (26,080), and Yate (28,350). In the south of the county, the areas around Filton and Kingswood, South Gloucestershire, Kingswood are densely populated and part of Bristol Built-up Area, Bristol built-up area. For Local government in England, local government purposes Gloucestershire comprises a non-metropolitan county, with six districts, and the Unitary authorities ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Karl Barry Sharpless
Karl Barry Sharpless (born April 28, 1941) is an American stereochemist. He is a two-time Nobel laureate in chemistry, known for his work on stereoselective reactions and click chemistry. Sharpless was awarded half of the 2001 Nobel Prize in Chemistry "for his work on chirally catalysed oxidation reactions", and one third of the 2022 prize, jointly with Carolyn R. Bertozzi and Morten P. Meldal, "for the development of click chemistry and bioorthogonal chemistry". Sharpless is the fifth person (in addition to two organizations) to have twice been awarded a Nobel prize, along with Marie Curie, John Bardeen, Linus Pauling and Frederick Sanger, and the third to have been awarded two prizes in the same discipline (after Bardeen and Sanger). Early life and education Sharpless was born April 28, 1941, in Philadelphia, Pennsylvania. His childhood was filled with summers at his family cottage on the Manasquan River in New Jersey. This is where Sharpless developed a love for fi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Bardeen
John Bardeen (; May 23, 1908 – January 30, 1991) was an American solid-state physicist. He is the only person to be awarded the Nobel Prize in Physics twice: first in 1956 with William Shockley and Walter Houser Brattain for their invention of the transistor; and again in 1972 with Leon Cooper and John Robert Schrieffer for their fundamental theory of superconductivity, known as the BCS theory. Born and raised in Wisconsin, Bardeen received a Ph.D. in physics from Princeton University. After serving in World War II, he was a researcher at Bell Labs and a professor at the University of Illinois. The transistor revolutionized the electronics industry, making possible the development of almost every modern electronic device, from telephones to computers, and ushering in the Information Age. Bardeen's developments in superconductivity—for which he was awarded his second Nobel Prize—are used in nuclear magnetic resonance spectroscopy (NMR), medical magnetic resonance ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Paul Berg
Paul Berg (June 30, 1926 – February 15, 2023) was an American biochemist and professor at Stanford University. He was the recipient of the Nobel Prize in Chemistry in 1980, along with Walter Gilbert and Frederick Sanger. The award recognized their contributions to basic research involving nucleic acids, especially recombinant DNA. Berg received his undergraduate education at Penn State University, where he majored in biochemistry. He received his PhD in biochemistry from Case Western Reserve University in 1952. Berg worked as a professor at Washington University School of Medicine and Stanford University School of Medicine, in addition to serving as the director of the Beckman Center for Molecular and Genetic Medicine. In addition to the Nobel Prize, Berg was presented with the National Medal of Science in 1983 and the National Library of Medicine Medal in 1986. Berg was a member of the Board of Sponsors for the ''Bulletin of the Atomic Scientists''. Early life and e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Walter Gilbert
Walter Gilbert (born March 21, 1932) is an American biochemist, physicist, molecular biology pioneer, and Nobel laureate. Education and early life Walter Gilbert was born in Boston, Massachusetts, on March 21, 1932, into a Jewish family, the son of Emma (Cohen), a child psychologist, and Richard V. Gilbert, an economist. When Gilbert was seven years old, the family moved to the Washington D.C. area so his father could work under Harry Hopkins on the New Deal brain trust. While living in Washington the family became friends with the family of I.F. Stone and Wally met Stone's oldest daughter, Celia, when they were both 8. They later married at age 21. He was educated at the Sidwell Friends School, and attended Harvard University for undergraduate and graduate studies, earning a baccalaureate in chemistry and physics in 1953 and a master's degree in physics in 1954. He studied for his doctorate at the University of Cambridge, where he earned a PhD in physics supervised by the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Central Dogma Of Molecular Biology
The central dogma of molecular biology deals with the flow of genetic information within a biological system. It is often stated as "DNA makes RNA, and RNA makes protein", although this is not its original meaning. It was first stated by Francis Crick in 1957, then published in 1958: He re-stated it in a ''Nature'' paper published in 1970: "The central dogma of molecular biology deals with the detailed residue-by-residue transfer of sequential information. It states that such information cannot be transferred back from protein to either protein or nucleic acid." A second version of the central dogma is popular but incorrect. This is the simplistic DNA → RNA → protein pathway published by James Watson in the first edition of ''The Molecular Biology of the Gene'' (1965). Watson's version differs from Crick's because Watson describes a two-step (DNA → RNA and RNA → protein) process as the central dogma. While the dogma as originally stated by Crick remains valid today, Wat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amino Acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although over 500 amino acids exist in nature, by far the most important are the 22 α-amino acids incorporated into proteins. Only these 22 appear in the genetic code of life. Amino acids can be classified according to the locations of the core structural functional groups ( alpha- , beta- , gamma- amino acids, etc.); other categories relate to polarity, ionization, and side-chain group type ( aliphatic, acyclic, aromatic, polar, etc.). In the form of proteins, amino-acid '' residues'' form the second-largest component (water being the largest) of human muscles and other tissues. Beyond their role as residues in proteins, amino acids participate in a number of processes such as neurotransmitter transport and biosynthesis. It is thought that they played a key role in enabling life on Earth and its emergence. Amino acids are formally named by the IUPAC- IUBMB Joint Commi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
