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Effective Dose (other)
Effective dose or internal dose may refer to: *Effective dose (pharmacology), a dose or concentration of a drug that produces a biological response *Effective dose (radiation), a measure of the stochastic effect on health risk that a radiation dose internal or external to whole or part of the body will have *In toxicology, the internal dose measured through biomonitoring In analytical chemistry, biomonitoring is the measurement of the body burden of toxic chemical compounds, elements, or their metabolites, in biological substances. Often, these measurements are done in blood and urine. Biomonitoring is performed ... See also * Dose (other) {{disambiguation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Effective Dose (pharmacology)
In pharmacology, an effective dose (ED) or effective concentration (EC) is a dose or concentration of a medication, drug that produces a biological response. The term effective dose is used when measurements are taken ''in vivo,'' while the term effective concentration is used when the measurements are taken ''in vitro''. Paracelsus#Toxicology, It has been stated that any substance can be toxic at a high enough dose. This concept was exemplified in 2007 when a California woman died of water intoxication in KDND#"Hold Your Wee for a Wii" contest, a contest sanctioned by a radio station. The line between efficacy and toxicity is dependent upon the particular patient, although the dose administered by a physician should fall into the predetermined therapeutic window of the drug. The importance of determining the therapeutic range of a drug cannot be overstated. This is generally defined by the range between the minimum effective dose (MED) and the maximum tolerated dose (MTD). The M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Effective Dose (radiation)
Effective dose is a dose quantity in the International Commission on Radiological Protection (ICRP) system of radiological protection.ICRP publication, 103 para 103 It is the tissue-weighted sum of the equivalent doses in all specified tissues and organs of the human body and represents the stochastic health risk to the whole body, which is the ''probability'' of cancer induction and genetic effects, of low levels of ionizing radiation. It takes into account the type of radiation and the nature of each organ or tissue being irradiated, and enables summation of organ doses due to varying levels and types of radiation, both internal and external, to produce an overall calculated effective dose. The SI unit for effective dose is the sievert (Sv) which represents a 5.5% chance of developing cancer. The effective dose is not intended as a measure of ''deterministic'' health effects, which is the ''severity'' of acute tissue damage that is certain to happen, that is measured by the quan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biomonitoring
In analytical chemistry, biomonitoring is the measurement of the body burden of toxic chemical compounds, elements, or their metabolites, in biological substances. Often, these measurements are done in blood and urine. Biomonitoring is performed in both environmental health, and in occupational safety and health as a means of exposure assessment and workplace health surveillance. The two best established environmental biomonitoring programs in representative samples of the general population are those of the United States and Germany, although population-based programs exist in a few other countries. In 2001, the U.S. Centers for Disease Control and Prevention (CDC) began to publish its biennial ''National Report on Human Exposure to Environmental Chemicals'', which reports a statistically representative sample of the U.S. population. Overview Biomonitoring involves the use of organisms to assess environmental contamination, such as of surrounding air or water. It can be done ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
