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Diego Antigen System
The Diego antigen (or blood group) system is composed of 21 blood factors or antigens carried on the Band 3 glycoprotein, also known as Anion Exchanger 1 (AE1). The antigens are inherited through various alleles of the gene SLC4A1 ( Solute carrier family 4), located on human chromosome 17. The AE1 glycoprotein is expressed only in red blood cells and, in a shortened form, in some cells in the kidney. The Diegoa antigen is fairly common in Indigenous peoples of the Americas (in both North and South America) and East Asians, but very rare or absent in most other populations, supporting the theory that the two groups share common ancestry. Types The Diego system is named after a pair of types, Diegoa (Dia) and Diegob (Dib), which differ by one amino acid in the AE1 glycoprotein, corresponding to one difference in the nucleotide sequence of the SLC4A1 gene. Dib is common or ubiquitous in all populations which have been screened for it, while Dia has been found only in Indigenous p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serology Interpretation Of Antibody Panel For Blood Group Antigens
Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given microorganism), against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease). In either case, the procedure is simple. Serological tests Serological tests are diagnostic methods that are used to identify antibodies and antigens in a patient's sample. Serological tests may be performed to diagnose infections and autoimmune illnesses, to check if a person has immunity to certain diseases, and in many other situations, such as determining an individual's blood type. Serological tests may also be used in forensic serology to investigate crime scene evidence. Several methods can be used to detect antibodies and antigens, including ELISA, agglutination, p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transfusion Reaction
Blood transfusion is the process of transferring blood products into a person's circulation intravenously. Transfusions are used for various medical conditions to replace lost components of the blood. Early transfusions used whole blood, but modern medical practice commonly uses only components of the blood, such as red blood cells, white blood cells, plasma, clotting factors and platelets. Red blood cells (RBC) contain hemoglobin, and supply the cells of the body with oxygen. White blood cells are not commonly used during transfusion, but they are part of the immune system, and also fight infections. Plasma is the "yellowish" liquid part of blood, which acts as a buffer, and contains proteins and important substances needed for the body's overall health. Platelets are involved in blood clotting, preventing the body from bleeding. Before these components were known, doctors believed that blood was homogeneous. Because of this scientific misunderstanding, many patients died becau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brazil
Brazil ( pt, Brasil; ), officially the Federative Republic of Brazil (Portuguese: ), is the largest country in both South America and Latin America. At and with over 217 million people, Brazil is the world's fifth-largest country by area and the List of countries and dependencies by population, seventh most populous. Its capital is Brasília, and List of cities in Brazil by population, its most populous city is São Paulo. The federation is composed of the union of the 26 States of Brazil, states and the Federal District (Brazil), Federal District. It is the largest country to have Portuguese language, Portuguese as an List of territorial entities where Portuguese is an official language, official language and the only one in the Americas; one of the most Multiculturalism, multicultural and ethnically diverse nations, due to over a century of mass Immigration to Brazil, immigration from around the world; and the most populous Catholic Church by country, Roman Catholic-major ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kaingang People
The Kaingang (also spelled ''caingangue'' in Portuguese or ''kanhgág'' in the Kaingang language) people are an Indigenous Brazilian ethnic group spread out over the three southern Brazilian states of Paraná, Santa Catarina and Rio Grande do Sul and the southeastern state of São Paulo. They are also called Caingang and Aweikoma, though the Kaingang and Aweikoma ( Xokleng) are now considered separate groups. The Kaigang people were the original first inhabitants of the province of Misiones in Argentina. Their language and culture is quite distinct from the neighboring Guaraní. It has been stated that the Kaingang rarely live long in one place causing them to move a lot, but some sources, such as Juracilda Veiga and ethnographic registers (José Francisco Tomás do Nascimento 1886, Telêmaco Borba 1908 etc.), indicate that Kaingang groups have a crucial relation with the land where they were born and their ancestors were buried. The Kaingang language is a member of the J ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Indigenous Peoples Of The Americas
The Indigenous peoples of the Americas are the inhabitants of the Americas before the arrival of the European settlers in the 15th century, and the ethnic groups who now identify themselves with those peoples. Many Indigenous peoples of the Americas were traditionally hunter-gatherers and many, especially in the Amazon basin, still are, but many groups practiced aquaculture and agriculture. While some societies depended heavily on agriculture, others practiced a mix of farming, hunting, and gathering. In some regions, the Indigenous peoples created monumental architecture, large-scale organized cities, city-states, chiefdoms, states, Realm, kingdoms, republics, Confederation, confederacies, and empires. Some had varying degrees of knowledge of engineering, architecture, mathematics, astronomy, writing, physics, medicine, planting and irrigation, geology, mining, metallurgy, sculpture, and gold smithing. Many parts of the Americas are still populated by Indigenous peoples; ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Japanese People
The are an East Asian ethnic group native to the Japanese archipelago."人類学上は，旧石器時代あるいは縄文時代以来，現在の北海道〜沖縄諸島（南西諸島）に住んだ集団を祖先にもつ人々。" () Japanese people constitute 97.9% of the population of the country of Japan. Worldwide, approximately 129 million people are of Japanese descent; of these, approximately 122.5 million are residents of Japan. People of Japanese ancestry who live outside Japan are referred to as , the Japanese diaspora. Depending on the context, the term may be limited or not to mainland Japanese people, specifically the Yamato (as opposed to Ryukyuan and Ainu people). Japanese people are one of the largest ethnic groups in the world. In recent decades, there has also been an increase in the number of multiracial people with both Japanese and non-Japanese roots, including half Japanese people. History Theories of origins Archaeological evidence ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chinese People
The Chinese people or simply Chinese, are people or ethnic groups identified with China, usually through ethnicity, nationality, citizenship, or other affiliation. Chinese people are known as Zhongguoren () or as Huaren () by speakers of standard Chinese, including those living in Greater China as well as overseas Chinese. Although both terms both refer to Chinese people, their usage depends on the person and context. The former term is commonly used to refer to the citizens of the People's Republic of China - especially mainland China. The term Huaren is used to refer to ethnic Chinese, and is more often used for those who reside overseas or are non-citizens of China. The Han Chinese are the largest ethnic group in China, comprising approximately 92% of its Mainland population.CIA Factbook "Han Chinese 91.6%" out of a r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Native Americans In The United States
Native Americans, also known as American Indians, First Americans, Indigenous Americans, and other terms, are the Indigenous peoples of the mainland United States ( Indigenous peoples of Hawaii, Alaska and territories of the United States are generally known by other terms). There are 574 federally recognized tribes living within the US, about half of which are associated with Indian reservations. As defined by the United States Census, "Native Americans" are Indigenous tribes that are originally from the contiguous United States, along with Alaska Natives. Indigenous peoples of the United States who are not listed as American Indian or Alaska Native include Native Hawaiians, Samoan Americans, and the Chamorro people. The US Census groups these peoples as " Native Hawaiian and other Pacific Islanders". European colonization of the Americas, which began in 1492, resulted in a precipitous decline in Native American population because of new diseases, wars, ethni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mongoloid
Mongoloid () is an obsolete racial grouping of various peoples indigenous to large parts of Asia, the Americas, and some regions in Europe and Oceania. The term is derived from a now-disproven theory of biological race. In the past, other terms such as " Mongolian race", "yellow", "Asiatic" and " Oriental" have been used as synonyms. The concept of dividing humankind into the Mongoloid, Caucasoid, and Negroid races was introduced in the 1780s by members of the Göttingen School of History. It was further developed by Western scholars in the context of racist ideologies during the age of colonialism. The organization has since been renamed the American Association of Biological Anthropologists. With the rise of modern genetics, the concept of distinct human races in a biological sense has become obsolete. In 2019, the American Association of Biological Anthropologists stated: "The belief in 'races' as natural aspects of human biology, and the structures of inequality (racism) t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Serum
Serum () is the fluid and solute component of blood which does not play a role in clotting. It may be defined as blood plasma without the clotting factors, or as blood with all cells and clotting factors removed. Serum includes all proteins not used in blood clotting; all electrolytes, antibodies, antigens, hormones; and any exogenous substances (e.g., drugs or microorganisms). Serum does not contain white blood cells ( leukocytes), red blood cells (erythrocytes), platelets, or clotting factors. The study of serum is serology. Serum is used in numerous diagnostic tests as well as blood typing. Measuring the concentration of various molecules can be useful for many applications, such as determining the therapeutic index of a drug candidate in a clinical trial. To obtain serum, a blood sample is allowed to clot (coagulation). The sample is then centrifuged to remove the clot and blood cells, and the resulting liquid supernatant is serum. Clinical and laboratory uses Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ABO Blood Group System
The ABO blood group system is used to denote the presence of one, both, or neither of the A and B antigens on erythrocytes. For human blood transfusions, it is the most important of the 43 different blood type (or group) classification systems currently recognized by the International Society of Blood Transfusions (ISBT) as of June 2021. A mismatch (very rare in modern medicine) in this, or any other serotype, can cause a potentially fatal adverse reaction after a transfusion, or an unwanted immune response to an organ transplant. The associated anti-A and anti-B antibodies are usually IgM antibodies, produced in the first years of life by sensitization to environmental substances such as food, bacteria, and viruses. The ABO blood types were discovered by Karl Landsteiner in 1901; he received the Nobel Prize in Physiology or Medicine in 1930 for this discovery. ABO blood types are also present in other primates such as apes and Old World monkeys. History Discovery The ABO ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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