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David Jack (scientist)
Sir David Jack (22 February 1924 – 8 November 2011) was a Scottish pharmacologist and medicinal chemist who specialised in the development of drugs for treating asthma. He was head of research and development at Glaxo from 1978 until 1987. Early life and education Jack was born the sixth and youngest child of a coal miner, in Markinch, Fife, Scotland. He attended Buckhaven High School before turning down a place at Edinburgh University to become an apprentice pharmacist. In 1944, having completed his apprenticeship, he began a BSc course in chemistry and pharmacy at the Royal Technical College, Glasgow. He won a number of undergraduate prizes and graduated with first class honours. Career He turned down an offer to study for a doctorate and instead worked as an assistant lecturer at the University of Glasgow. In 1951 he joined the pharmaceutical company Glaxo Laboratories, moving to Smith Kline and French in 1953. In 1961 he became director of research at Allen and Hanbu ...
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Markinch
Markinch (, Scottish Gaelic: Marc Innis) is both a village and a parish in the heart of Fife, Scotland. According to an estimate taken in 2008, the village has a population of 2,420. The civil parish had a population of 16,530 (in 2011).Census of Scotland 2011, Table KS101SC – Usually Resident Population, publ. by National Records of Scotland. Web site http://www.scotlandscensus.gov.uk/ retrieved March 2016. See “Standard Outputs”, Table KS101SC, Area type: Civil Parish 1930 Markinch is east of Fife's administrative centre, Glenrothes, and preceded Cupar as Fife's place of warranty and justice prior to the 13th century. History The earliest indications of human activity around Markinch are Balfarg henge and Balbirnie Stone Circle, in an area now incorporated into the new town of Glenrothes, but formerly part of Markinch Parish. They are said to date back to 3,000 BC from the Neolithic period.Fiet ''Old Markinch'' pp.3-4.Fife Council ''Glenrothes and Surrounding Villa ...
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The Daily Telegraph
''The Daily Telegraph'', known online and elsewhere as ''The Telegraph'', is a British daily broadsheet conservative newspaper published in London by Telegraph Media Group and distributed in the United Kingdom and internationally. It was founded by Arthur B. Sleigh in 1855 as ''The Daily Telegraph and Courier''. ''The Telegraph'' is considered a newspaper of record in the UK. The paper's motto, "Was, is, and will be", was included in its emblem which was used for over a century starting in 1858. In 2013, ''The Daily Telegraph'' and ''The Sunday Telegraph'', which started in 1961, were merged, although the latter retains its own editor. It is politically conservative and supports the Conservative Party (UK), Conservative Party. It was moderately Liberalism, liberal politically before the late 1870s.Dictionary of Nineteenth Century Journalismp 159 ''The Telegraph'' has had a number of news scoops, including the outbreak of World War II by rookie reporter Clare Hollingworth, desc ...
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Allen And Hanburys
Allen and Hanburys Ltd was a British pharmaceutical manufacturer, absorbed by Glaxo Laboratories in 1958. GlaxoSmithKline, its successor company, used the Allen and Hanburys name for the specialist respiratory division until beginning to phase it out in 2013. In 2021, the name was trademarked in the United States as part of the formation of Allen & Hanburys Inc., an American pharmaceutical and consumer products company focused on Pediatrics, Dermatology and Respiratory Care exclusively within the United States. History The business was founded in 1715 in Old Plough Court, Lombard Street, London, by Silvanus Bevan, a Welshman, apothecary and a Quaker. Bevan and his brother, Timothy, who became his partner and later succeeded him, were known for their just dealings and the integrity and quality of their drugs. The company grew into a respected pharmaceutical centre and had established a strong reputation with American doctors by the late 18th century. The West Indies was also ...
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Glaxo Laboratories
GSK plc (an acronym from its former name GlaxoSmithKline plc) is a British multinational pharmaceutical and biotechnology company with headquarters in London. It was established in 2000 by a merger of Glaxo Wellcome and SmithKline Beecham, which was itself a merger of a number of pharmaceutical companies around the Smith, Kline & French firm. GSK is the tenth largest pharmaceutical company and No. 294 on the 2022 ''Fortune'' Global 500, ranked behind other pharmaceutical companies China Resources, Sinopharm, Johnson & Johnson, Pfizer, Roche, AbbVie, Novartis, Bayer, and Merck Sharp & Dohme. The company has a primary listing on the London Stock Exchange and is a constituent of the FTSE 100 Index. As of February 2024, it had a market capitalisation of £69 billion, the eighth largest on the London Stock Exchange. The company developed the first malaria vaccine, RTS,S, which it said in 2014, it would make available for five per cent above cost. Legacy products developed a ...
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Glasgow
Glasgow is the Cities of Scotland, most populous city in Scotland, located on the banks of the River Clyde in Strathclyde, west central Scotland. It is the List of cities in the United Kingdom, third-most-populous city in the United Kingdom and the 27th-most-populous city in Europe, and comprises Wards of Glasgow, 23 wards which represent the areas of the city within Glasgow City Council. Glasgow is a leading city in Scotland for finance, shopping, industry, culture and fashion, and was commonly referred to as the "second city of the British Empire" for much of the Victorian era, Victorian and Edwardian eras. In , it had an estimated population as a defined locality of . More than 1,000,000 people live in the Greater Glasgow contiguous urban area, while the wider Glasgow City Region is home to more than 1,800,000 people (its defined functional urban area total was almost the same in 2020), around a third of Scotland's population. The city has a population density of 3,562 p ...
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Pharmacist
A pharmacist, also known as a chemist in English in the Commonwealth of Nations, Commonwealth English, is a healthcare professional who is knowledgeable about preparation, mechanism of action, clinical usage and legislation of medications in order to dispense them safely to the public and to provide consultancy services. A pharmacist also often serves as a primary care provider in the community and offers services, such as health screenings and immunizations. Pharmacists undergo university or graduate-level education to understand the biochemical mechanisms and actions of drugs, drug uses, therapeutic roles, side effects, potential drug interactions, and monitoring parameters. In developing countries, a diploma course from approved colleges qualifies one for pharmacist role. This is mated to anatomy, physiology, and pathophysiology. Pharmacists interpret and communicate this specialized knowledge to patients, physicians, and other health care providers. Among other licensing ...
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Edinburgh University
The University of Edinburgh (, ; abbreviated as ''Edin.'' in post-nominals) is a public research university based in Edinburgh, Scotland. Founded by the town council under the authority of a royal charter from King James VI in 1582 and officially opened in 1583, it is one of Scotland's four ancient universities and the sixth-oldest university in continuous operation in the English-speaking world. The university played a crucial role in Edinburgh becoming a leading intellectual centre during the Scottish Enlightenment and contributed to the city being nicknamed the " Athens of the North". The three main global university rankings ( ARWU, THE, and QS) place the University of Edinburgh within their respective top 40. It is a member of several associations of research-intensive universities, including the Coimbra Group, League of European Research Universities, Russell Group, Una Europa, and Universitas 21. In the fiscal year ending 31 July 2024, the university had a total ...
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Buckhaven High School
Buckhaven High School was a six-year co-educational non-denominational comprehensive school in Buckhaven, Fife, Scotland. In the past, Buckhaven was Levenmouth's high school for pupils who passed their qualifying exam. The school's motto was ''Perseverando''. The school's origins dated back to the 1860s and for many years it occupied a site in College Street, Buckhaven. The most recent building was in use from 1957 until 2016, and in 1976 an extension was completed. The catchments for the school were Buckhaven Primary, Methilhill Primary, East Wemyss Primary, Coaltown of Wemyss Primary, Parkhill Primary, Kirkton of Largo Primary and Kennoway Primary. They also received pupils from out with the catchments who submitted placing requests. Merger In June 2012 Fife Council proposed that the school should merge with neighbouring Kirkland High School and Community College to create Levenmouth Academy. The plans were approved in April 2014 and the new school opened to pupils on 17 Au ...
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The Times
''The Times'' is a British Newspaper#Daily, daily Newspaper#National, national newspaper based in London. It began in 1785 under the title ''The Daily Universal Register'', adopting its modern name on 1 January 1788. ''The Times'' and its sister paper ''The Sunday Times'' (founded in 1821), are published by Times Media, since 1981 a subsidiary of News UK, in turn wholly owned by News Corp. ''The Times'' and ''The Sunday Times'' were founded independently and have had common ownership only since 1966. It is considered a newspaper of record in the UK. ''The Times'' was the first newspaper to bear that name, inspiring numerous other papers around the world. In countries where these other titles are popular, the newspaper is often referred to as or , although the newspaper is of national scope and distribution. ''The Times'' had an average daily circulation of 365,880 in March 2020; in the same period, ''The Sunday Times'' had an average weekly circulation of 647,622. The two ...
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Scotland
Scotland is a Countries of the United Kingdom, country that is part of the United Kingdom. It contains nearly one-third of the United Kingdom's land area, consisting of the northern part of the island of Great Britain and more than 790 adjacent Islands of Scotland, islands, principally in the archipelagos of the Hebrides and the Northern Isles. To the south-east, Scotland has its Anglo-Scottish border, only land border, which is long and shared with England; the country is surrounded by the Atlantic Ocean to the north and west, the North Sea to the north-east and east, and the Irish Sea to the south. The population in 2022 was 5,439,842. Edinburgh is the capital and Glasgow is the most populous of the cities of Scotland. The Kingdom of Scotland emerged as an independent sovereign state in the 9th century. In 1603, James VI succeeded to the thrones of Kingdom of England, England and Kingdom of Ireland, Ireland, forming a personal union of the Union of the Crowns, three kingdo ...
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Asthma
Asthma is a common long-term inflammatory disease of the airways of the lungs. It is characterized by variable and recurring symptoms, reversible airflow obstruction, and easily triggered bronchospasms. Symptoms include episodes of wheezing, coughing, chest tightness, and shortness of breath. A sudden worsening of asthma symptoms sometimes called an 'asthma attack' or an 'asthma exacerbation' can occur when allergens, pollen, dust, or other particles, are inhaled into the lungs, causing the bronchioles to constrict and produce mucus, which then restricts oxygen flow to the alveoli. These may occur a few times a day or a few times per week. Depending on the person, asthma symptoms may become worse at night or with exercise. Asthma is thought to be caused by a combination of genetic and environmental factors. Environmental factors include exposure to air pollution and allergens. Other potential triggers include medications such as aspirin and beta blockers. Diag ...
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Medicinal Chemist
Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs, their biological properties, and their quantitative structure-activity relationships (QSAR). Medicinal chemistry is a highly interdisciplinary science combining organic chemistry with biochemistry, computational chemistry, pharmacology, molecular biology, statistics, and physical chemistry. Compounds used as medicines are most often organic compounds, which are often divided into the broad classes of small organic molecules (e.g., atorvastatin, fluticasone, clopidogrel) and "biologics" (infliximab, erythropoietin, insulin glargine), the latter of which are most often medicinal preparations of proteins (natural and recombinant antibodi ...
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