Nuclear Organization
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Nuclear Organization
Nuclear organization refers to the spatial organization and dynamics of chromatin within a cell nucleus during interphase. There are many different levels and scales of nuclear organization. At the smallest scale, DNA is packaged into units called nucleosomes, which compacts DNA about 7-fold. In addition, nucleosomes protect DNA from damage and carry epigenetic information. Positions of nucleosomes determine accessibility of DNA to transcription factors. At the intermediate scale, DNA looping can physically bring together DNA elements that would otherwise be separated by large distances. These interactions allow regulatory signals to cross over large genomic distances—for example, from enhancers to promoters. At a larger scale, chromosomes are organized into two compartments labelled A ("active") and B ("inactive"), which are further subdivided into sub-compartments. At the largest scale, entire chromosomes segregate into distinct regions called chromosome terr ...
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Nuclear Technology
Nuclear technology is technology that involves the nuclear reactions of atomic nucleus, atomic nuclei. Among the notable nuclear technologies are nuclear reactors, nuclear medicine and nuclear weapons. It is also used, among other things, in smoke detectors and gun sights. History and scientific background Discovery The vast majority of common, natural phenomena on Earth only involve gravity and electromagnetism, and not nuclear reactions. This is because atomic nuclei are generally kept apart because they contain positive electrical charges and therefore repel each other. In 1896, Henri Becquerel was investigating phosphorescence in uranium salts when he discovered a new phenomenon which came to be called radioactivity. He, Pierre Curie and Marie Curie began investigating the phenomenon. In the process, they isolated the element radium, which is highly radioactive. They discovered that radioactive materials produce intense, penetrating rays of three distinct sorts, which ...
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