Moonlighting Proteins
Protein moonlighting is a phenomenon by which a protein can perform more than one function. It is an example ogene sharing Ancestral moonlighting proteins originally possessed a single function but, through evolution, acquired additional functions. Many proteins that moonlight are enzymes; others are receptors, ion channels or Chaperone (protein), chaperones. The most common primary function of moonlighting proteins is enzyme catalysis, enzymatic catalysis, but these enzymes have acquired secondary non-enzymatic roles. Some examples of functions of moonlighting proteins secondary to catalysis include signal transduction, transcriptional regulation, apoptosis, motility, and structural. Protein moonlighting occurs widely in nature. Protein moonlighting through gene sharing differs from the use of a single gene to generate different proteins by alternative splicing, alternative RNA splicing, DNA rearrangement, or posttranslational modification, post-translational processing. It is ...
[...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]