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Jennifer Doudna
Jennifer Anne Doudna (; born February 19, 1964) is an American biochemist who has pioneered work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a method for genome editing." She is the Li Ka-shing, Li Ka Shing Chancellor, Chancellor's Professor, Chair Professor in the department of chemistry and the department of molecular and cell biology at the University of California, Berkeley. She has been an investigator with the Howard Hughes Medical Institute since 1997. In 2012, Doudna and Emmanuelle Charpentier were the first to propose that CRISPR-Cas9 (enzymes from bacteria that control microbial immunity) could be used for programmable editing of genomes, which has been called one of the most significant discoveries in the history of biology. Since then, Doudna has been a leading figure in what is referred to as the "CRISPR revolution" ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Awards And Honors Received By Jennifer Doudna
This list of awards and honors received by Jennifer Doudna comprehensively shows the awards, honors, honorary degrees, fellowships and other recognition received by Jennifer Doudna, an American biochemist at the University of California, Berkeley. She has received many prestigious awards and fellowships for her numerous contributions to biochemistry and genetics, and is most famous for her work on CRISPR-Cas9 genome editing technology. Doudna and Emmanuelle Charpentier were awarded the 2020 Nobel Prize in Chemistry "for the development of a method for genome editing." Awards * 1996 Beckman Young Investigators Award * 1999 NAS Award for Initiatives in Research * 2000 Alan T. Waterman Award ''for innovative research that led to the development of a technique that facilitates crystallization of large RNA molecules; for determining the crystal structures of catalytic RNA molecules and an RNA molecule that forms the ribonucleoprotein core of the signal recognition particle; and for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Colorado, Boulder
The University of Colorado Boulder (CU Boulder, CU, or Colorado) is a public research university in Boulder, Colorado, United States. Founded in 1876, five months before Colorado became a state, it is the flagship university of the University of Colorado system. CU Boulder is a member of the Association of American Universities, considered a Public Ivy and is classified among R1: Doctoral Universities – Very high research activity. The university consists of nine colleges and schools and offers over 150 academic programs, enrolling more than 35,000 students as of January 2022. In 2021, the university attracted the support of over $634 million for research and spent $536 million on research and development according to the National Science Foundation, ranking it 50th in the nation. It receives the most NASA astrophysics technology grants of all academic institutions and is the only university in the world that has sent instruments to all planets in the Solar System. The Col ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emmanuelle Charpentier
Emmanuelle Marie Charpentier (; born 11 December 1968) is a French professor and researcher in microbiology, genetics, and biochemistry. As of 2015, she has been a director at the Max Planck Institute for Infection Biology in Berlin. In 2018, she founded an independent research institute, the Max Planck Unit for the Science of Pathogens. In 2020, Charpentier and American biochemist Jennifer Doudna of the University of California, Berkeley, were awarded the Nobel Prize in Chemistry "for the development of a method for genome editing" (through CRISPR gene editing, CRISPR). This was the first science Nobel Prize ever won by two women only. Early life and education Charpentier's paternal grandfather, surnamed Sinanian, was an Armenians, Armenian who escaped to France during the Armenian Genocide and met his wife in Marseille. She was born in 1968 in Juvisy-sur-Orge in France and studied biochemistry, microbiology, and genetics at the Pierre and Marie Curie University (which became ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CRISPR Gene Editing
CRISPR gene editing (; pronounced like "crisper"; an abbreviation for "clustered regularly interspaced short palindromic repeats") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified. It is based on a simplified version of the bacterial CRISPR-Cas9 antiviral defense system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing existing genes to be removed or new ones added ''in vivo''. The technique is considered highly significant in biotechnology and medicine as it enables editing genomes ''in vivo'' and is precise, cost-effective, and efficient. It can be used in the creation of new medicines, agriculture, agricultural products, and genetically modified organisms, or as a means of controlling pathogens and pest control, pests. It also offers potential in the treatment of inherited genetic diseases as well as diseases arisi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biochemist
Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of "biological chemist." Biochemists also research how certain chemical reactions happen in cells and Tissue (biology), tissues and observe and record the effects of Product (chemistry), products in food additives and Medication, medicines. Biochemist researchers focus on playing and constructing research experiments, mainly for developing new products, updating existing products and analyzing said products. It is also the responsibility of a biochemist to present their research findings and create Grant writing, grant proposals to obtain Funding of science, funds for future research. Biochemists study aspects of the immune system, the expressions of genes, isolating, analyzing, and synthesizing different products, mutations that lead to ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Encyclopædia Britannica Online
An encyclopedia is a reference work or compendium providing summaries of knowledge, either general or special, in a particular field or discipline. Encyclopedias are divided into articles or entries that are arranged alphabetically by article name or by thematic categories, or else are hyperlinked and searchable. Encyclopedia entries are longer and more detailed than those in most dictionaries. Generally speaking, encyclopedia articles focus on ''factual information'' concerning the subject named in the article's title; this is unlike dictionary entries, which focus on linguistic information about words, such as their etymology, meaning, pronunciation, use, and grammatical forms.Béjoint, Henri (2000)''Modern Lexicography'', pp. 30–31. Oxford University Press. Encyclopedias have existed for around 2,000 years and have evolved considerably during that time as regards language (written in a major international or a vernacular language), size (few or many volumes), intent ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lei Stanley Qi
Lei "Stanley" Qi () is an associate professor in the department of bioengineering, and the department of chemical and systems biology at Stanford University. Qi led the development of the first catalytically dead Cas9 lacking endonuclease activity (dCas9), which is the basis for CRISPR interference (CRISPRi). His laboratory subsequently developed CRISPR-Genome Organization (CRISPR-GO) based on dCas9 and CRISPR-Transcriptome Organization (CRISPR-TO) based on dCas13. Qi is a co-inventor of the University of California patent on the CRISPR gene-editing technology. Early life and education Qi obtained his B.S. in physics and math from Tsinghua University, China, Master in physics from UC Berkeley, and PhD in bioengineering from UC Berkeley. During his PhD work at Berkeley, he studied synthetic biology with Adam Arkin, and was the first to explore engineering the CRISPR for targeted gene editing and gene regulation with Jennifer Doudna Jennifer Anne Doudna (; born February 19, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Janice Chen
Janice Chen is the co-founder and chief technology officer of Mammoth Biosciences, a Brisbane, California-based company, founded in 2018, that is developing diagnostic tests using CRISPR. She received her B.S. degree from Johns Hopkins University and her Ph.D. in Molecular and Cell Biology. from the University of California, Berkeley, where she worked in the lab of CRISPR pioneer Jennifer Doudna. Awards and honors Along with two of her co-founders at Mammoth Biosciences, Chen was named to the 2019 Forbes 30 Under 30 Healthcare list and 2020 Business Insider's 30 Under 40 in Healthcare. She was also selected to the 2020 Endpoints Top 20 Women in Biopharma, and 35 Innovators Under 35 in MIT Technology Review in 2021. Personal life Chen grew up in Salt Lake City, Utah, and is one of five siblings. Her youngest brother is Olympic figure skater Nathan Chen. Their parents had immigrated to the United States from China in 1988. Chen competed in chess tournaments, where she was oft ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rachel Haurwitz
Rachel Elizabeth Haurwitz (born May 20, 1985) is an American biochemist and structural biologist. She is the co-founder, chief executive officer, and president of Caribou Biosciences, a genome editing company. Early life and education Haurwitz was born on May 20, 1985. She grew up in Austin, Texas. Her mother is an elementary school teacher and her father, an environmental journalist. Haurwitz began researching RNA during her undergraduate years. She attended Harvard College where she earned an undergraduate degree. In 2007, she began doctoral studies at University of California, Berkeley. At the age of 21, Haurwitz began working as a graduate student in Jennifer Doudna's laboratory, in 2008 where she completed her doctorate in molecular and cell biology. Haurwitz originally intended on becoming an intellectual property lawyer for biotechnology patents but later chose to continue in science. Career In 2011, Haurwitz and Doudna co-founded Caribou Biosciences, a gene editing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thomas Cech
Thomas Robert Cech (born 8 December 1947) is an American chemist who shared the 1989 Nobel Prize in Chemistry with Sidney Altman for their discovery of the catalytic properties of RNA. Cech discovered that RNA could itself cut strands of RNA, suggesting that life might have started as RNA. He found that RNA can not only transmit instructions, but can act as a catalyst to speed up the necessary reactions. He has also studied telomeres, and his lab discovered an enzyme, TERT (telomerase reverse transcriptase), which is part of the process of restoring telomeres after they are shortened during cell division. As president of Howard Hughes Medical Institute (2000-2008) he promoted science education, and he teaches an undergraduate chemistry course at the University of Colorado. Early life and career Cech was born to parents of Czech origin (his grandfather was Czech, his other grandparents were first-generation Americans) in Chicago. He grew up in Iowa City, Iowa. In junio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jack Szostak
Jack William Szostak (born November 9, 1952) is a Canadian American biologist of Polish British descent, Nobel Prize laureate, university professor at the University of Chicago, former professor of genetics at Harvard Medical School, and Alexander Rich Distinguished Investigator at Massachusetts General Hospital, Boston. Szostak has made significant contributions to the field of genetics. His achievement helped scientists to map the location of genes in mammals and to develop techniques for manipulating genes. His research findings in this area are also instrumental to the Human Genome Project. He was awarded the 2009 Nobel Prize for Physiology or Medicine, along with Elizabeth Blackburn and Carol W. Greider, for the discovery of how chromosomes are protected by telomeres. Early life and education Szostak grew up in Montreal and Ottawa. Although Szostak does not speak Polish, he stated in an interview with Wprost weekly that he remembers his Polish roots. He attended Riverda ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, San Francisco
The University of California, San Francisco (UCSF) is a Public university, public Land-grant university, land-grant research university in San Francisco, California, United States. It is part of the University of California system and is dedicated entirely to health science and life science. It conducts research and teaching in Medicine, medical and biology, biological sciences. UCSF was founded as Toland Medical College in 1864. In 1873, it became affiliated with the University of California as its Medical Department. In the same year, it incorporated the California College of Pharmacy and in 1881 it established a dentistry school. Its facilities were located in both Berkeley, California, Berkeley and San Francisco. In 1964, the school gained full administrative independence as a campus of the UC system, headed by its own chancellor, and in 1970 it gained its current name. Historically based at List of neighborhoods in San Francisco#Parnassus, Parnassus Heights with satellite ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
