Efferent Neurons
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Efferent Neurons
Efferent nerve fibers are axons (nerve fibers) of efferent neurons that exit a particular region. These terms have a slightly different meaning in the context of the peripheral nervous system (PNS) and central nervous system (CNS). The efferent fiber is a long process projecting far from the soma (biology), neuron's body that carries action potential, nerve impulses away from the central nervous system toward the peripheral effector organs (muscles and glands). A bundle of these fibers constitute an efferent nerve. The opposite direction of neural activity is afferent conduction, which carries impulses by way of the afferent nerve fibers of sensory neurons. In the nervous system, there is a "closed loop" system of sensation, decision, and reactions. This process is carried out through the activity of sensory neurons, interneurons, and motor neurons. In the CNS, afferent and efferent projections can be from the perspective of any given brain region. That is, each brain region h ...
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Spinal Cord
The spinal cord is a long, thin, tubular structure made up of nervous tissue that extends from the medulla oblongata in the lower brainstem to the lumbar region of the vertebral column (backbone) of vertebrate animals. The center of the spinal cord is hollow and contains a structure called the central canal, which contains cerebrospinal fluid. The spinal cord is also covered by meninges and enclosed by the neural arches. Together, the brain and spinal cord make up the central nervous system. In humans, the spinal cord is a continuation of the brainstem and anatomically begins at the occipital bone, passing out of the foramen magnum and then enters the spinal canal at the beginning of the cervical vertebrae. The spinal cord extends down to between the first and second lumbar vertebrae, where it tapers to become the cauda equina. The enclosing bony vertebral column protects the relatively shorter spinal cord. It is around long in adult men and around long in adult women. The diam ...
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Cell (biology)
The cell is the basic structural and functional unit of all life, forms of life. Every cell consists of cytoplasm enclosed within a Cell membrane, membrane; many cells contain organelles, each with a specific function. The term comes from the Latin word meaning 'small room'. Most cells are only visible under a light microscope, microscope. Cells Abiogenesis, emerged on Earth about 4 billion years ago. All cells are capable of Self-replication, replication, protein synthesis, and cell motility, motility. Cells are broadly categorized into two types: eukaryotic cells, which possess a Cell nucleus, nucleus, and prokaryotic, prokaryotic cells, which lack a nucleus but have a nucleoid region. Prokaryotes are single-celled organisms such as bacteria, whereas eukaryotes can be either single-celled, such as amoebae, or multicellular organism, multicellular, such as some algae, plants, animals, and fungi. Eukaryotic cells contain organelles including Mitochondrion, mitochondria, which ...
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Intrafusal Muscle Fiber
Intrafusal muscle fibers are skeletal muscle fibers that serve as specialized sensory organs ( proprioceptors). They detect the amount and rate of change in length of a muscle.Casagrand, Janet (2008) ''Action and Movement: Spinal Control of Motor Units and Spinal Reflexes.'' University of Colorado, Boulder. They constitute the muscle spindle, and are innervated by both sensory (afferent) and motor (efferent) fibers. Intrafusal muscle fibers are not to be confused with extrafusal muscle fibers, which contract, generating skeletal movement and are innervated by alpha motor neurons. Structure Types There are two types of intrafusal muscle fibers: nuclear bag fibers and nuclear chain fibers. They bear two types of sensory ending, known as annulospiral and flower-spray endings. Both ends of these fibers contract, but the central region only stretches and does not contract. Intrafusal muscle fibers are walled off from the rest of the muscle by an outer connective tissue ...
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Gamma Motor Neuron
A gamma motor neuron (γ motor neuron), also called gamma motoneuron, or fusimotor neuron, is a type of lower motor neuron that takes part in the process of muscle contraction, and represents about 30% of ( Aγ) fibers going to the muscle. Like alpha motor neurons, their cell bodies are located in the anterior grey column of the spinal cord. They receive input from the reticular formation of the pons in the brainstem. Their axons are smaller than those of the alpha motor neurons, with a diameter of only 5  μm. Unlike the alpha motor neurons, gamma motor neurons do not directly adjust the lengthening or shortening of muscles. However, their role is important in keeping muscle spindles taut, thereby allowing the continued firing of alpha neurons, leading to muscle contraction. These neurons also play a role in adjusting the sensitivity of muscle spindles. The presence of myelination in gamma motor neurons allows a conduction velocity of 4 to 24 meters per second, si ...
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Extrafusal Muscle Fiber
Extrafusal muscle fibers are the standard skeletal muscle fibers that are innervated by alpha motor neurons and generate tension by contracting, thereby allowing for skeletal movement. They make up the large mass of skeletal striated muscle tissue and are attached to bone by fibrous tissue extensions (tendons). Each alpha motor neuron and the extrafusal muscle fibers innervated by it make up a motor unit. The connection between the alpha motor neuron and the extrafusal muscle fiber is a neuromuscular junction, where the neuron's signal, the action potential, is transduced to the muscle fiber by the neurotransmitter acetylcholine. Extrafusal muscle fibers are not to be confused with intrafusal muscle fibers, which are innervated by sensory nerve endings in central noncontractile parts and by gamma motor neurons in contractile ends and thus serve as a sensory proprioceptor. Extrafusal muscle fibers can be generated in vitro (in a dish) from pluripotent stem cells through d ...
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Alpha Motor Neuron
Alpha (α) motor neurons (also called alpha motoneurons), are large, multipolar neuron, multipolar lower motor neurons of the brainstem and spinal cord. They innervate extrafusal muscle fibers of skeletal muscle and are directly responsible for initiating their muscle contraction, contraction. Alpha motor neurons are distinct from gamma motor neurons, which innervate intrafusal muscle fibers of muscle spindles. While their cell body, cell bodies are found in the central nervous system (CNS), α motor neurons are also considered part of the somatic nervous system—a branch of the peripheral nervous system (PNS)—because their axons extend into the periphery to innervate skeletal muscles. An alpha motor neuron and the muscle fibers it innervates comprise a motor unit. A motor neuron pool contains the cell bodies of all the alpha motor neurons involved in contracting a single muscle. Location Alpha motor neurons (α-MNs) innervating the head and neck are found in the brainstem; t ...
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Special Visceral Efferent Fiber
Special visceral efferent fibers (SVE) are the efferent nerve fibers that provide motor innervation to the muscles of the pharyngeal arches in humans, and the branchial arches in fish. Some sources prefer the term "branchiomotor" or "branchial efferent". The only nerves containing SVE fibers are cranial nerves: the trigeminal nerve (V), the facial nerve (VII), the glossopharyngeal nerve (IX), the vagus nerve (X) and the accessory nerve (XI).Drake et al. (2010), Gray's Anatomy for Students, 2nd Ed., Churchill Livingstone. See also * General somatic efferent fiber (GSE) * General visceral efferent fiber General visceral efferent fibers (GVE), visceral efferents or autonomic efferents are the efferent nerve fibers of the autonomic nervous system (also known as the ''visceral efferent nervous system'') that provide motor innervation to smooth musc ... (GVE) References Neuroanatomy {{Neuroanatomy-stub ...
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General Visceral Efferent Fiber
General visceral efferent fibers (GVE), visceral efferents or autonomic efferents are the efferent nerve fibers of the autonomic nervous system (also known as the ''visceral efferent nervous system'') that provide motor innervation to smooth muscle, cardiac muscle, and glands (contrast with special visceral efferent (SVE) fibers) through postganglionic varicosities. GVE fibers may be either sympathetic or parasympathetic. Cranial and sacral spinal fibers are parasympathetic GVE fibers, while thoracic and lumbar spinal cord give rise to sympathetic GVE fibers. The cranial nerves containing GVE fibers include the oculomotor nerve (CN III), the facial nerve (CN VII), the glossopharyngeal nerve (CN IX) and the vagus nerve (CN X).Mehta, Samir et al. Step-Up: A High-Yield, Systems-Based Review for the USMLE Step 1. Baltimore, MD: LWW, 2003. Additional images File:Gray840.png, Sympathetic connections of the ciliary and superior cervical ganglia. File:Gray839.png, Autonomic nervous ...
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General Somatic Efferent Fiber
The general (spinal) somatic efferent neurons (GSE, somatomotor, or somatic motor fibers) arise from motor neuron cell bodies in the ventral horns of the gray matter within the spinal cord. They exit the spinal cord through the ventral roots, carrying motor impulses to skeletal muscle through a neuromuscular junction. Of the somatic efferent neurons, there exist subtypes. * Alpha motor neurons (α) target extrafusal muscle fibers. * Gamma motor neurons (γ) target intrafusal muscle fibres Cranial nerves also supply their own somatic efferent neurons to the extraocular muscles and some of the muscles of the tongue. See also * Nerve fiber * Efferent nerve * General visceral efferent fiber General visceral efferent fibers (GVE), visceral efferents or autonomic efferents are the efferent nerve fibers of the autonomic nervous system (also known as the ''visceral efferent nervous system'') that provide motor innervation to smooth musc ... (GVE) * Special visceral efferent fi ...
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Effector
Effector may refer to: *Effector (biology), a molecule that binds to a protein and thereby alters the activity of that protein * ''Effector'' (album), a music album by the Experimental Techno group Download * ''EFFector'', a publication of the Electronic Frontier Foundation See also * Effexor, a brand name for the antidepressant venlafaxine * Bacterial effector protein, proteins secreted by bacterial pathogens into the cells of their host *Effector cell * End effector, the device at the end of a robotic arm *Affect (other) Affect may refer to: * Affect (education) * Affect (linguistics), attitude or emotion that a speaker brings to an utterance * Affect (philosophy) * Affect (psychology), the experience of feeling or emotion ** Affect display, signs of emotion, su ...
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Medulla Oblongata
The medulla oblongata or simply medulla is a long stem-like structure which makes up the lower part of the brainstem. It is anterior and partially inferior to the cerebellum. It is a cone-shaped neuronal mass responsible for autonomic (involuntary) functions, ranging from vomiting to sneezing. The medulla contains the cardiovascular center, the respiratory center, vomiting and vasomotor centers, responsible for the autonomic functions of breathing, heart rate and blood pressure as well as the sleep–wake cycle. "Medulla" is from Latin, ‘pith or marrow’. And "oblongata" is from Latin, ‘lengthened or longish or elongated'. During embryonic development, the medulla oblongata develops from the myelencephalon. The myelencephalon is a secondary brain vesicle which forms during the maturation of the rhombencephalon, also referred to as the hindbrain. The bulb is an archaic term for the medulla oblongata. In modern clinical usage, the word bulbar (as in bulbar palsy) is r ...
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Grey Matter
Grey matter, or gray matter in American English, is a major component of the central nervous system, consisting of neuronal cell bodies, neuropil ( dendrites and unmyelinated axons), glial cells ( astrocytes and oligodendrocytes), synapses, and capillaries. Grey matter is distinguished from white matter in that it contains numerous cell bodies and relatively few myelinated axons, while white matter contains relatively few cell bodies and is composed chiefly of long-range myelinated axons. The colour difference arises mainly from the whiteness of myelin. In living tissue, grey matter actually has a very light grey colour with yellowish or pinkish hues, which come from capillary blood vessels and neuronal cell bodies. Structure Grey matter refers to unmyelinated neurons and other cells of the central nervous system. It is present in the brain, brainstem and cerebellum, and present throughout the spinal cord. Grey matter is distributed at the surface of the cerebral hemisp ...
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