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Edward Jenner
Edward Jenner (17 May 1749 – 26 January 1823) was an English physician and scientist who pioneered the concept of vaccines and created the smallpox vaccine, the world's first vaccine. The terms ''vaccine'' and ''vaccination'' are derived from ''Variolae vaccinae'' ('pustules of the cow'), the term devised by Jenner to denote cowpox. He used it in 1798 in the title of his ''Inquiry into the Variolae vaccinae known as the Cow Pox'', in which he described the protective effect of cowpox against smallpox. Jenner is often called "the father of immunology", and his work is said to have saved "more lives than any other man". In Jenner's time, smallpox killed around 10% of the global population, with the number as high as 20% in towns and cities where infection spread more easily. In 1821, he was appointed physician to King George IV, and was also made mayor of Berkeley and justice of the peace. He was a member of the Royal Society. In the field of zoology, he was among the firs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Berkeley, Gloucestershire
Berkeley ( ) is a market town and civil parishes in England, civil parish in the Stroud (district), Stroud District in Gloucestershire, England. It lies in the Vale of Berkeley between the east bank of the River Severn and the M5 motorway. The town is noted for Berkeley Castle, where the imprisoned Edward II of England, King Edward II is believed to have been murdered, as well as the birthplace of the physician Edward Jenner, pioneer of the smallpox vaccine, the world's first vaccine. Geography Berkeley lies midway between Bristol and Gloucester, on a small hill in the Vale of Berkeley. The town is on the Little Avon River, which flows into the Severn at Pil (placename), Berkeley Pill. The Little Avon was tidal, and so navigable, for some distance inland (as far as Berkeley itself and the Sea Mills at Ham) until a 'tidal reservoir' was implemented at Berkeley Pill in the late 1960s. Governance An Wards and electoral divisions of the United Kingdom, electoral ward in the same n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aristotle
Aristotle (; 384–322 BC) was an Ancient Greek philosophy, Ancient Greek philosopher and polymath. His writings cover a broad range of subjects spanning the natural sciences, philosophy, linguistics, economics, politics, psychology, and the arts. As the founder of the Peripatetic school of philosophy in the Lyceum (classical), Lyceum in Athens, he began the wider Aristotelianism, Aristotelian tradition that followed, which set the groundwork for the development of modern science. Little is known about Aristotle's life. He was born in the city of Stagira (ancient city), Stagira in northern Greece during the Classical Greece, Classical period. His father, Nicomachus (father of Aristotle), Nicomachus, died when Aristotle was a child, and he was brought up by a guardian. At around eighteen years old, he joined Plato's Platonic Academy, Academy in Athens and remained there until the age of thirty seven (). Shortly after Plato died, Aristotle left Athens and, at the request ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chipping Sodbury
Chipping Sodbury is a market town and civil parish in the unitary authority area of South Gloucestershire, in the county of Gloucestershire, England. It is situated 13 miles (21 km) north-east of Bristol and directly east of Yate. The town was founded in the 12th century by William le Gros. It is the main settlement in the civil parish of Sodbury, which also includes the village of Old Sodbury. At the 2011 census the population of Chipping Sodbury was 5,045, but the town has since become part of a larger built-up area due to the rapid expansion of nearby neighbouring town, Yate. The two towns are contiguous with one another. Governance An electoral ward in the same name (not Sodbury) exists. This ward starts in the north at Chipping Sodbury Golf Course and stretches south to Dodington. The total population of the ward taken at the 2011 census was 6,834. In 1931 the parish had a population of 973. On 1 April 1946 the parish was abolished to form Sodbury. Transport Eas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surgeon
In medicine, a surgeon is a medical doctor who performs surgery. Even though there are different traditions in different times and places, a modern surgeon is a licensed physician and received the same medical training as physicians before specializing in surgery. In some countries and jurisdictions, the title of 'surgeon' is restricted to maintain the integrity of the craft group in the medical profession. A specialist regarded as a legally recognized surgeon includes podiatry, dentistry, and veterinary medicine. It is estimated that surgeons perform over 300 million surgical procedures globally each year. History The first person to document a surgery was the 6th century BC Indian physician-surgeon, Sushruta. He specialized in cosmetic plastic surgery and even documented an open rhinoplasty procedure.Papel, Ira D. and Frodel, John (2008) ''Facial Plastic and Reconstructive Surgery''. Thieme Medical Pub. His Masterpiece, magnum opus ''Suśruta-saṃhitā'' is one of the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Smallpox
Smallpox was an infectious disease caused by Variola virus (often called Smallpox virus), which belongs to the genus '' Orthopoxvirus''. The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, making smallpox the only human disease to have been eradicated to date. The initial symptoms of the disease included fever and vomiting. This was followed by formation of ulcers in the mouth and a skin rash. Over a number of days, the skin rash turned into the characteristic fluid-filled blisters with a dent in the center. The bumps then scabbed over and fell off, leaving scars. The disease was transmitted from one person to another primarily through prolonged face-to-face contact with an infected person or rarely via contaminated objects. Prevention was achieved mainly through the smallpox vaccine. Once the disease had developed, certain antiviral medications could poten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Variolation
Variolation was the method of inoculation first used to immunize individuals against smallpox (''Variola'') with material taken from a patient or a recently variolated individual, in the hope that a mild, but protective, infection would result. Only 1–2% of those variolated died from the intentional infection compared to 30% who contracted smallpox naturally. Variolation is no longer used today. It was replaced by the smallpox vaccine, a safer alternative. This in turn led to the development of the many vaccines now available against other diseases. The procedure was most commonly carried out by inserting/rubbing powdered smallpox scabs or fluid from pustules into superficial scratches made in the skin. The virus was normally spread through the air, infecting first the mouth, nose, or respiratory tract, before spreading throughout the body via the lymphatic system. In contrast, infection of the skin usually led to a milder, localized infection, but, crucially, still induced immun ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inoculation
Inoculation is the act of implanting a pathogen or other microbe or virus into a person or other organism. It is a method of artificially inducing immunity against various infectious diseases. The term "inoculation" is also used more generally to refer to intentionally depositing microbes into any growth medium, as into a Petri dish used to culture the microbe, or into food ingredients for making cultured foods such as yoghurt and fermented beverages such as beer and wine. This article is primarily about the use of inoculation for producing immunity against infection. Inoculation has been used to eradicate smallpox and to markedly reduce other infectious diseases such as polio. Although the terms "inoculation", "vaccination", and "immunization" are often used interchangeably, there are important differences. Inoculation is the act of implanting a pathogen or microbe into a person or other recipient; vaccination is the act of implanting or giving someone a vaccine specifical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cirencester
Cirencester ( , ; see #Pronunciation, below for more variations) is a market town and civil parish in the Cotswold District of Gloucestershire, England. Cirencester lies on the River Churn, a tributary of the River Thames. It is the List of settlements in Gloucestershire by population, eighth largest settlement in Gloucestershire and the largest town within the Cotswolds. It is the home of the Royal Agricultural University, the oldest agricultural college in the English-speaking world, founded in 1840. The town had a population of 20,229 in 2021. The town is northwest of Swindon, southeast of Gloucester, west of Oxford and northeast of Bristol. The Roman name for the town was Corinium, which is thought to have been associated with the ancient British tribe of the ''Dobunni'', having the same root word as the River Churn. The earliest known reference to the town was by Ptolemy in AD 150. The town's Corinium Museum has an extensive Roman Britain, Roman collection. Cirences ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wotton-under-Edge
Wotton-under-Edge is a market town and civil parish in the Stroud district of Gloucestershire, England. Near the southern fringe of the Cotswolds The Cotswolds ( ) is a region of central South West England, along a range of rolling hills that rise from the meadows of the upper River Thames to an escarpment above the Severn Valley and the Vale of Evesham. The area is defined by the bedroc ..., the Cotswold Way long-distance footpath passes through the town. History The first record of the town is in an Anglo-Saxon Royal Charter of Edmund I of England, King Edmund I, who in AD 940 leased Hide (unit), four hides of land in ''Wudetun'' to Eadric. The name ''Wudetun'' means the enclosure, homestead or village (''tun'') in or near the wood (''wude''). The "Edge" refers to the limestone escarpment of the Cotswold Edge which includes the hills of Wotton Hill and Tor Hill that flank the town. In the 1086 Domesday Book listing, Wotton was in the Hundred (county division), hundred ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
