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Combinatorial Chemistry
Combinatorial chemistry comprises chemical synthetic methods that make it possible to prepare a large number (tens to thousands or even millions) of compounds in a single process. These compound libraries can be made as mixtures, sets of individual compounds or chemical structures generated by computer software. Combinatorial chemistry can be used for the synthesis of small molecules and for peptides. Strategies that allow identification of useful components of the libraries are also part of combinatorial chemistry. The methods used in combinatorial chemistry are applied outside chemistry, too. Introduction The basic principle of combinatorial chemistry is to prepare libraries of a very large number of compounds and identify those which are useful as potential drugs or agrochemicals. This relies on high-throughput screening which is capable of assessing the output at sufficient scale. Although combinatorial chemistry has only really been taken up by industry since the 1990s, its ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Synthesis
Chemical synthesis (chemical combination) is the artificial execution of chemical reactions to obtain one or several products. This occurs by physical and chemical manipulations usually involving one or more reactions. In modern laboratory uses, the process is reproducible and reliable. A chemical synthesis involves one or more compounds (known as '' reagents'' or ''reactants'') that will experience a transformation under certain conditions. Various reaction types can be applied to formulate a desired product. This requires mixing the compounds in a reaction vessel, such as a chemical reactor or a simple round-bottom flask. Many reactions require some form of processing (" work-up") or purification procedure to isolate the final product. The amount produced by chemical synthesis is known as the '' reaction yield''. Typically, yields are expressed as a mass in grams (in a laboratory setting) or as a percentage of the total theoretical quantity that could be produced based ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cycle 3,4 Vágott
Cycle, cycles, or cyclic may refer to: Anthropology and social sciences * Cyclic history, a theory of history * Cyclical theory, a theory of American political history associated with Arthur Schlesinger, Sr. * Social cycle, various cycles in social sciences ** Business cycle, the downward and upward movement of gross domestic product (GDP) around its ostensible, long-term growth trend Arts, entertainment, and media Films * ''Cycle'' (2008 film), a Malayalam film * ''Cycle'' (2017 film), a Marathi film Literature * ''Cycle'' (magazine), an American motorcycling enthusiast magazine * Literary cycle, a group of stories focused on common figures Music Musical terminology * Cycle (music), a set of musical pieces that belong together ** Cyclic form, a technique of construction involving multiple sections or movements ** Interval cycle, a collection of pitch classes generated from a sequence of the same interval class ** Song cycle, individually complete songs desig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oligopeptides
An oligopeptide ('' oligo-'', "a few"), is a peptide consisting of two to twenty amino acids, including dipeptides, tripeptides, tetrapeptides, and other polypeptides. Some of the major classes of naturally occurring oligopeptides include aeruginosins, cyanopeptolins, microcystins, microviridins, microginins, anabaenopeptins, and cyclamides. Microcystins are best studied because of their potential toxicity impact in drinking water. A review of some oligopeptides found that the largest class are the cyanopeptolins (40.1%), followed by microcystins (13.4%). Production Oligopeptide classes are produced by nonribosomal peptides synthases (NRPS), except cyclamides and microviridins are synthesized through ribosomic pathways. Examples Examples of oligopeptides include: * Amanitins - Cyclic peptides taken from carpophores of several different mushroom species. They are potent inhibitors of RNA polymerases in most eukaryotic species, the prevent the production of mRNA and protein ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Example Of A Solid-phase Supported Dye Indicating Ligand Binding
Example may refer to: * ''exempli gratia'' (e.g.), usually read out in English as "for example" * .example, reserved as a domain name that may not be installed as a top-level domain of the Internet ** example.com, example.net, example.org, and example.edu: second-level domain names reserved for use in documentation as examples * HMS ''Example'' (P165), an Archer-class patrol and training vessel of the Royal Navy Arts * ''The Example'', a 1634 play by James Shirley * ''The Example'' (comics), a 2009 graphic novel by Tom Taylor and Colin Wilson * Example (musician), the British dance musician Elliot John Gleave (born 1982) * ''Example'' (album), a 1995 album by American rock band For Squirrels See also * Exemplar (other), a prototype or model which others can use to understand a topic better * Exemplum, medieval collections of short stories to be told in sermons * Eixample The Eixample (, ) is a district of Barcelona between the old city (Ciutat Vella) a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Use Of A Solid-supported Polyamine That Is Used To Scavenge Excess Reagent
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Use may refer to: * Use (law), an obligation on a person to whom property has been conveyed * Use (liturgy), subset of a Christian liturgical ritual family used by a particular group or diocese * Use–mention distinction, the distinction between using a word and mentioning it * Consumption (economics) ** Resource depletion, use to the point of lack of supply ** Psychological manipulation, in a form that treats a person is as a means to an end * Rental utilization, quantification of the use of assets to be continuously let See also * Use case, in software and systems engineering * User story, in software development and product management * USE (other) * Used (other) * User (other) Ancient Egyptian roles * User (ancient Egyptian official), an ancient Egyptian nomarch (governor) of the Eighth Dynasty * Useramen, an ancient Egyptian vizier also called "User" Other uses * User (computing), a person (or software) using an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromatography
In chemical analysis, chromatography is a laboratory technique for the Separation process, separation of a mixture into its components. The mixture is dissolved in a fluid solvent (gas or liquid) called the ''mobile phase'', which carries it through a system (a column, a capillary tube, a plate, or a sheet) on which a material called the ''stationary phase'' is fixed. Because the different constituents of the mixture tend to have different affinities for the stationary phase and are retained for different lengths of time depending on their interactions with its surface sites, the constituents travel at different apparent velocities in the mobile fluid, causing them to separate. The separation is based on the differential partitioning between the mobile and the stationary phases. Subtle differences in a compound's partition coefficient result in differential retention on the stationary phase and thus affect the separation. Chromatography may be ''preparative'' or ''analytical' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Insoluble Polymer
In chemistry, solubility is the ability of a chemical substance, substance, the solute, to form a solution (chemistry), solution with another substance, the solvent. Insolubility is the opposite property, the inability of the solute to form such a solution. The extent of the solubility of a substance in a specific solvent is generally measured as the concentration of the solute in a wikt:saturated#Chemistry, saturated solution, one in which no more solute can be dissolved. At this point, the two substances are said to be at the solubility equilibrium. For some solutes and solvents, there may be no such limit, in which case the two substances are said to be "miscibility, miscible in all proportions" (or just "miscible"). The solute can be a solid, a liquid, or a gas, while the solvent is usually solid or liquid. Both may be pure substances, or may themselves be solutions. Gases are always miscible in all proportions, except in very extreme situations,J. de Swaan Arons and G. A. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
