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Broca's Area
Broca's area, or the Broca area (, also , ), is a region in the frontal lobe of the dominant Cerebral hemisphere, hemisphere, usually the left, of the Human brain, brain with functions linked to speech production. Language processing in the brain, Language processing has been linked to Broca's area since Pierre Paul Broca reported impairments in two patients. They had lost the ability to speak after injury to the posterior inferior frontal gyrus (pars triangularis) (BA45) of the brain. Since then, the approximate region he identified has become known as Broca's area, and the deficit in language production as Broca's aphasia, also called expressive aphasia. Broca's area is now typically defined in terms of the pars opercularis and pars triangularis of the inferior frontal gyrus, represented in Korbinian Brodmann, Brodmann's Brodmann area, cytoarchitectonic map as Brodmann area 44 and Brodmann area 45 of the dominant hemisphere. Functional magnetic resonance imaging (fMRI) has show ...
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Brodmann Area 44
Brodmann area 44, or BA44, is part of the frontal cortex in the human brain. Situated just anterior to premotor cortex ( BA6) and on the lateral surface, inferior to BA9. This area is also known as pars opercularis (of the inferior frontal gyrus), and it refers to a subdivision of the cytoarchitecturally defined frontal region of cerebral cortex. In the human it corresponds approximately to the opercular part of the inferior frontal gyrus. Thus, it is bounded caudally by the inferior precentral sulcus (H) and rostrally by the anterior ascending limb of lateral sulcus (H). It surrounds the diagonal sulcus (H). In the depth of the lateral sulcus it borders on the insula. Cytoarchitectonically it is bounded caudally and dorsally by the agranular frontal area 6, dorsally by the granular frontal area 9 and rostrally by the triangular part of inferior frontal gyrus ( Brodmann area 45 BA 45). Functions Together with left-hemisphere BA45, the left hemisphere BA44 comprises Br ...
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Pars Opercularis
The inferior frontal gyrus (IFG; also gyrus frontalis inferior) is the lowest positioned gyrus of the frontal gyri, of the frontal lobe, and is part of the prefrontal cortex. Its superior border is the inferior frontal sulcus (which divides it from the middle frontal gyrus), its inferior border is the lateral sulcus (which divides it from the superior temporal gyrus) and its posterior border is the inferior precentral sulcus. Above it is the middle frontal gyrus, behind it is the precentral gyrus. The inferior frontal gyrus contains Broca's area, which is involved in language processing and speech production. Structure The inferior frontal gyrus is highly convoluted and has three cytoarchitecturally diverse regions. The three subdivisions are an opercular part, a triangular part, and an orbital part. These divisions are marked by two rami arising from the lateral sulcus. The ascending ramus separates the opercular and triangular parts. The anterior (horizontal) ramus separate ...
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Talairach Coordinates
Jean Talairach (January 15, 1911 – March 15, 2007) was a psychiatrist and neurosurgery, neurosurgeon who practiced at the Sainte-Anne Hospital Center in Paris, and who is noted for the Talairach coordinates, which are relevant in stereotactic surgery, stereotactic neurosurgery. Early life Talairach was the son of a pianist, and learned the cello to a professional level. However, instead of pursuing a musical career, he then developed a passion for geometry and architecture, and was particularly interested in the lecture halls in the medieval medical college in Montpellier. This interest, in turn, led him to become interested in medicine, especially psychiatry. In 1938 he traveled to Paris to study medicine. He completed his doctoral studies at Ste. Anne's Hospital, one of the oldest and most renowned hospitals in France. World War II During the German occupation of France in the second World War, Talairach joined the French resistance. He created a detailed map of the tunne ...
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Sulcus (neuroanatomy)
In neuroanatomy, a sulcus (Latin: "furrow"; : sulci) is a shallow Sulcus (morphology), depression or groove in the cerebral cortex. One or more sulci surround a gyrus (pl. gyri), a ridge on the surface of the cortex, creating the characteristic folded appearance of the brain in humans and most other mammals. The larger sulci are also called Sulcus (morphology)#Brain, fissures. The cortex develops in the fetal stage of corticogenesis, preceding the cortical folding stage known as gyrification. The large fissures and main sulci are the first to develop. Mammals that have a folded cortex are known as ''gyrencephalic'', and the small-brained mammals that have a smooth cortex, such as rats and mice are termed lissencephaly, lissencephalic. Structure Sulci, the grooves, and gyri, the folds or ridges, make up the gyrification, folded surface of the cerebral cortex. Larger or deeper sulci are also often termed fissures. The folded cortex creates a larger surface area for the brain in h ...
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Topography
Topography is the study of the forms and features of land surfaces. The topography of an area may refer to the landforms and features themselves, or a description or depiction in maps. Topography is a field of geoscience and planetary science and is concerned with local detail in general, including not only relief, but also natural, artificial, and cultural features such as roads, land boundaries, and buildings. In the United States, topography often means specifically relief, even though the USGS topographic maps record not just elevation contours, but also roads, populated places, structures, land boundaries, and so on. Topography in a narrow sense involves the recording of relief or terrain, the three-dimensional quality of the surface, and the identification of specific landforms; this is also known as geomorphometry. In modern usage, this involves generation of elevation data in digital form ( DEM). It is often considered to include the graphic representation of t ...
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Brodmann Cytoarchitectonics 45
Brodmann is a German surname. Notable people with the surname include: *Ines Brodmann (born 1985), Swiss orienteer *Korbinian Brodmann (1868–1918), German neurologist *Mario Brodmann (born 1966), Swiss former ice hockey forward *René Brodmann (1933–2000), Swiss football defender See also *Brodmann area A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. The concept was first introduced by the German anatomist Korbinian B ..., a region in the brain cortex * Michael L. Brodman, American gynecologist and obstetrician {{surname, Brodmann German-language surnames ...
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Brain Tumor
A brain tumor (sometimes referred to as brain cancer) occurs when a group of cells within the Human brain, brain turn cancerous and grow out of control, creating a mass. There are two main types of tumors: malignant (cancerous) tumors and benign tumor, benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and metastasis, secondary tumors, which most commonly have spread from tumors located outside the brain, known as brain metastasis tumors. All types of brain tumors may produce symptoms that vary depending on the size of the tumor and the part of the brain that is involved. Where symptoms exist, they may include headaches, seizures, problems with visual perception, vision, vomiting and cognition, mental changes. Other symptoms may include difficulty walking, speaking, with sensations, or unconsciousness. The cause of most brain tumors is unknown, though up to 4% of brain cancers may be caused by CT scan radiation. Uncommo ...
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Brodmann Area 6
Brodmann area 6 (BA6) is part of the frontal cortex in the human brain. Situated just anterior to the primary motor cortex ( BA4), it is composed of the premotor cortex and, medially, the supplementary motor area (SMA). This large area of the frontal cortex is believed to play a role in planning complex, coordinated movements. Brodmann area 6 is also called agranular frontal area 6 in humans because it lacks an internal granular cortical layer (layer IV). It is a subdivision of the cytoarchitecturally defined precentral region of cerebral cortex. In the human brain, it is located on the portions of the precentral gyrus that are not occupied by Brodmann area 4; furthermore, BA6 extends onto the caudal portions of the superior frontal and middle frontal gyri. It extends from the cingulate sulcus on the medial aspect of the hemisphere to the lateral sulcus on the lateral aspect. It is bounded rostrally by the granular frontal region and caudally by the gigantopyramidal area 4 (Br ...
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Orbital Part Of Inferior Frontal Gyrus
The orbital part of inferior frontal gyrus also known as the pars orbitalis is the orbital part of the inferior frontal gyrus. In humans, this region is bordered by the triangular part of the inferior frontal gyrus (pars triangularis) and, surrounding the anterior horizontal limb of the lateral sulcus, a portion of the opercular part of inferior frontal gyrus The inferior frontal gyrus (IFG; also gyrus frontalis inferior) is the lowest positioned gyrus of the frontal gyri, of the frontal lobe, and is part of the prefrontal cortex. Its superior border is the inferior frontal sulcus (which divides it ... (pars opercularis). Bounded caudally by the anterior ascending limb of the lateral sulcus, it borders on the insula in the depth of the lateral sulcus. It is bordered anteriorly/inferiorly by the lateral orbital sulcus. Cytoarchitectonically it is most closely represented by Brodmann area 47 (BA47).Brodmann, K. (1909). Vergleichende Lokalisationslehre der Grosshirnrind ...
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Functional Magnetic Resonance Imaging
Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area of the brain is in use, blood flow to that region also increases. The primary form of fMRI uses the blood-oxygen-level dependent (BOLD) contrast, discovered by Seiji Ogawa in 1990. This is a type of specialized brain and body scan used to map neuron, neural activity in the brain or spinal cord of humans or other animals by imaging the change in blood flow (hemodynamic response) related to energy use by brain cells. Since the early 1990s, fMRI has come to dominate brain mapping research because it does not involve the use of injections, surgery, the ingestion of substances, or exposure to ionizing radiation. This measure is frequently corrupted by noise from various sources; hence, statistical procedures are used to extract the underlying si ...
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Brodmann Area
A Brodmann area is a region of the cerebral cortex, in the human or other primate brain, defined by its cytoarchitecture, or histological structure and organization of cells. The concept was first introduced by the German anatomist Korbinian Brodmann in the early 20th century. Brodmann mapped the human brain based on the varied cellular structure across the cortex and identified 52 distinct regions, which he numbered 1 to 52. These regions, or Brodmann areas, correspond with diverse functions including sensation, motor control, and cognition. History Brodmann areas were originally defined and numbered by the German anatomist Korbinian Brodmann based on the cytoarchitectural organization of neurons he observed in the cerebral cortex using the Nissl method of cell staining. Brodmann published his maps of cortical areas in humans, monkeys, and other species in 1909, along with many other findings and observations regarding the general cell types and laminar organization of t ...
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