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Brain Death
Brain death is the permanent, irreversible, and complete loss of Electroencephalography, brain function, which may include cessation of involuntary activity (e.g., Control of ventilation#Control of respiratory rhythm, breathing) necessary to sustain life. It differs from persistent vegetative state, in which the person is alive and some autonomic functions remain. It is also distinct from comas as long as some brain and bodily activity and function remain, and it is also not the same as the condition locked-in syndrome. A differential diagnosis can medically distinguish these differing conditions. Brain death is used as an indicator of legal death in many jurisdictions, but it is Medical definition of death, defined inconsistently and often confused by the public. Various parts of the brain may keep functioning when others do not anymore, bringing questions about whether they should truly be considered dead. The term "brain death" has been used to refer to various combinations. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Death
Death is the end of life; the irreversible cessation of all biological functions that sustain a living organism. Death eventually and inevitably occurs in all organisms. The remains of a former organism normally begin to decompose shortly after death. Some organisms, such as '' Turritopsis dohrnii'', are biologically immortal; however, they can still die from means other than aging. Death is generally applied to whole organisms; the equivalent for individual components of an organism, such as cells or tissues, is necrosis. Something that is not considered an organism, such as a virus, can be physically destroyed but is not said ''to die'', as a virus is not considered alive in the first place. As of the early 21st century, 56 million people die per year. The most common reason is aging, followed by cardiovascular disease, which is a disease that affects the heart or blood vessels. As of 2022, an estimated total of almost 110 billion humans have died, or rou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lazarus Sign
The Lazarus sign or Lazarus reflex is a reflex movement in brain-dead or brainstem failure patients, which causes them to briefly raise their arms and drop them crossed on their chests (in a position similar to some Egyptian mummies). The phenomenon is named after Lazarus of Bethany, whom the Biblical Gospel of John says was raised from the dead by Jesus. Causes Like the knee jerk reflex, the Lazarus sign is an example of a reflex mediated by a reflex arc—a neural pathway which passes via the spinal column but not through the brain. As a consequence, the movement is possible in brain-dead patients whose organs have been kept functioning by life-support machines, precluding the use of complex involuntary motions as a test for brain activity. Some neurologists believe that hypoxia could lead to Lazarus sign but this theory lost strength as incidence of new cases in patients with normal oxygen level began to arise. It has been suggested by neurologists studying the phe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Locked-in Syndrome
Locked-in syndrome (LIS), also known as pseudocoma, is a condition in which a patient is aware but cannot move or communicate verbally due to complete paralysis of nearly all voluntary muscles in their body except for vertical eye movements and blinking. This is due to quadriplegia and bulbar palsy. The individual is conscious and sufficiently intact cognitively to be able to communicate with eye movements. Electroencephalography results are normal in locked-in syndrome as these individuals have retained brain activity such as sleep-wake cycles and attention that is detectable. Fred Plum and Jerome B. Posner coined the term for this disorder in 1966. Locked-in syndrome can be separated into different subcategories based on symptom severity. This consists of classic locked-in syndrome, characterized by the inability to move distal limbs and facial muscles, but retained ability to blink and move eyes vertically, with preserved cognition and consciousness. Incomplete locked-in s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Law
Medical law is the branch of law which concerns the prerogatives and responsibilities of medical professionals and the rights of the patient. It should not be confused with medical jurisprudence, which is a branch of medicine, rather than a branch of law. Branches Branches of medical law include: * the law of torts (i.e. medical malpractice); *criminal law in relation to medical practice and treatment; * the ethics of medical practice; * health law and regulation. Administrative law Health professional's fitness to practise is regulated by medical licensing. If concerns are raised regarding a health professional the licensing body may choose to suspend or reject their license. Education to work in medical law A career in Medical Law usually requires a bachelor's degree in bioethics, government, healthcare management or policy, public or global health, or (outside the US) law. Career descriptions in the field of medical law * Reviewing medical documents, files, and re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Jurisprudence
Medical jurisprudence or legal medicine is the branch of science and medicine involving the study and application of scientific and medical knowledge to legal problems, such as inquests, and in the field of law. As modern medicine is a legal creation, regulated by the state, and medicolegal cases involving death, rape, paternity, etc. require a medical practitioner to produce evidence and appear as an expert witness, these two fields have traditionally been interdependent. Forensic medicine, which includes forensic pathology, is a narrower frontline field which involves the collection, documentation, analysis and presentation of objective information (medical evidence) for use in the legal system. When investigating a death, forensic pathologists: * perform autopsies when required * may be appointed as coroners to investigate cases of suspicious death * determine the cause of death and all other factors that relate to the body directly * may attend crime scenes * frequently ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Operational Definition
An operational definition specifies concrete, replicable procedures designed to represent a construct. In the words of American psychologist S.S. Stevens (1935), "An operation is the performance which we execute in order to make known a concept." For example, an operational definition of "fear" (the construct) often includes measurable physiologic responses that occur in response to a perceived threat. Thus, "fear" might be operationally defined as specified changes in heart rate, electrodermal activity, pupil dilation, and blood pressure. Overview An operational definition is designed to model or represent a concept or theoretical definition, also known as a construct. Scientists should describe the operations (procedures, actions, or processes) that define the concept with enough specificity such that other investigators can replicate their research. Operational definitions are also used to define system states in terms of a specific, publicly accessible process of preparatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Organ Donation
Organ donation is the process when a person authorizes an organ (anatomy), organ of their own to be removed and organ transplantation, transplanted to another person, #Legislation and global perspectives, legally, either by consent while the donor is alive, through a Authorization, legal authorization for deceased donation made prior to death, or for deceased donations through the authorization by the De jure, legal next of Kinship, kin. Donation may be for research or, more commonly, healthy transplantable organs and tissues may be donated to be transplanted into another person. Common transplantations include kidney transplantation, kidneys, heart transplantation, heart, liver transplantation, liver, pancreas transplantation, pancreas, intestine transplantation, intestines, lung transplantation, lungs, bone transplantation, bones, bone marrow transplantation, bone marrow, skin transplantation, skin, and cornea transplantation, corneas. Some organs and tissues can be donated ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ventilation (physiology)
Breathing (spiration or ventilation) is the rhythmical process of moving air into ( inhalation) and out of ( exhalation) the lungs to facilitate gas exchange with the internal environment, mostly to flush out carbon dioxide and bring in oxygen. All aerobic creatures need oxygen for cellular respiration, which extracts energy from the reaction of oxygen with molecules derived from food and produces carbon dioxide as a waste product. Breathing, or external respiration, brings air into the lungs where gas exchange takes place in the alveoli through diffusion. The body's circulatory system transports these gases to and from the cells, where cellular respiration takes place. The breathing of all vertebrates with lungs consists of repetitive cycles of inhalation and exhalation through a highly branched system of tubes or airways which lead from the nose to the alveoli. The number of respiratory cycles per minute is the breathing or respiratory rate, and is one of the fou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brainstem Death
Brainstem death is a clinical syndrome defined by the absence of reflexes with pathways through the brainstem – the "stalk" of the brain, which connects the spinal cord to the mid-brain, cerebellum and cerebral hemispheres – in a deeply comatose, ventilator-dependent patient. Identification of this state carries a very grave prognosis for survival; cessation of heartbeat often occurs within a few days, although it may continue for weeks if intensive support is maintained.A Code of Practice for the Diagnosis and Confirmation of Death. Academy of Medical Royal Colleges, London, 2008 In the United Kingdom, death can be certified on the basis of a formal diagnosis of brainstem death, so long as this is done in accordance with a procedure established in "A Code of Practice for the Diagnosis and Confirmation of Death", published in 2008 by the Academy of Medical Royal Colleges. The premise of this is that a person is dead when consciousness and the ability to breathe are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brainstem
The brainstem (or brain stem) is the posterior stalk-like part of the brain that connects the cerebrum with the spinal cord. In the human brain the brainstem is composed of the midbrain, the pons, and the medulla oblongata. The midbrain is continuous with the thalamus of the diencephalon through the tentorial notch, and sometimes the diencephalon is included in the brainstem. The brainstem is very small, making up around only 2.6 percent of the brain's total weight. It has the critical roles of regulating heart and respiratory system, respiratory function, helping to control heart rate and breathing rate. It also provides the main motor and sensory nerve supply to the face and neck via the cranial nerves. Ten pairs of cranial nerves come from the brainstem. Other roles include the regulation of the central nervous system and the body's sleep cycle. It is also of prime importance in the conveyance of motor and sensory pathways from the rest of the brain to the body, and from the b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Subject Headings
Medical Subject Headings (MeSH) is a comprehensive controlled vocabulary for the purpose of indexing Academic journal, journal articles and books in the Life science, life sciences. It serves as a thesaurus of index terms that facilitates searching. Created and updated by the United States National Library of Medicine (NLM), it is used by the MEDLINE/PubMed article database and by NLM's catalog of book holdings. MeSH is also used by ClinicalTrials.gov registry to classify which diseases are studied by trials registered in ClinicalTrials. MeSH was introduced in the 1960s, with the NLM's own index catalogue and the subject headings of the Quarterly Cumulative Index Medicus (1940 edition) as precursors. The yearly printed version of MeSH was discontinued in 2007; MeSH is now available only online. It can be browsed and downloaded free of charge through PubMed. Originally in English, MeSH has been translated into numerous other languages and allows retrieval of documents from differ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cerebrum
The cerebrum (: cerebra), telencephalon or endbrain is the largest part of the brain, containing the cerebral cortex (of the two cerebral hemispheres) as well as several subcortical structures, including the hippocampus, basal ganglia, and olfactory bulb. In the human brain, the cerebrum is the uppermost region of the central nervous system. The cerebrum prenatal development, develops prenatally from the forebrain (prosencephalon). In mammals, the Dorsum (biology), dorsal telencephalon, or Pallium (neuroanatomy), pallium, develops into the cerebral cortex, and the ventral telencephalon, or Pallium (neuroanatomy), subpallium, becomes the basal ganglia. The cerebrum is also divided into approximately symmetric Lateralization of brain function, left and right cerebral hemispheres. With the assistance of the cerebellum, the cerebrum controls all voluntary actions in the human body. Structure The cerebrum is the largest part of the brain. Depending upon the position of the animal, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
