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Blood Pressure
Blood pressure (BP) is the pressure of Circulatory system, circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system. When used without qualification, the term "blood pressure" refers to the pressure in a brachial artery, where it is most commonly measured. Blood pressure is usually expressed in terms of the systolic pressure (maximum pressure during one Cardiac cycle, heartbeat) over diastolic pressure (minimum pressure between two heartbeats) in the cardiac cycle. It is measured in Millimetre of mercury, millimetres of mercury (mmHg) above the surrounding atmospheric pressure, or in Pascal (unit), kilopascals (kPa). The difference between the systolic and diastolic pressures is known as pulse pressure, while the average pressure during a cardiac cycle is known as mean arterial pressure. Blood pressure is one of the vital signs—together with respiratory rate, heart rate, Oxygen saturation (me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sphygmomanometer
A sphygmomanometer ( ), also known as a blood pressure monitor, blood pressure machine, or blood pressure gauge, is a device used to measure blood pressure, composed of an inflatable cuff to collapse and then release the artery under the cuff in a controlled manner, and a mercury or aneroid manometer to measure the pressure. Manual sphygmomanometers are used with a stethoscope when using the auscultatory technique. A sphygmomanometer consists of an inflatable cuff, a measuring unit (the mercury manometer, or aneroid gauge), and a mechanism for inflation which may be a manually operated bulb and valve or a pump operated electrically. Etymology The word ''sphygmomanometer'' uses the combining form of '' sphygmo-'' + '' manometer''. The roots involved are as follows: Greek ''sphygmos'' "pulse", plus the scientific term '' manometer'' (from French ''manomètre''), i.e. "pressure meter", itself coined from ''manos'' "thin, sparse", and ''metron'' "measure". Most sphygmom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxygen Saturation (medicine)
Oxygen saturation is the fraction of oxygen-saturated haemoglobin relative to total haemoglobin (unsaturated + saturated) in the blood. The human body requires and regulates a very precise and specific balance of oxygen in the blood. Normal arterial blood oxygen saturation levels in humans are 96–100 percent. If the level is below 90 percent, it is considered low and called hypoxemia. Arterial blood oxygen levels below 80 percent may compromise organ function, such as the brain and heart, and should be promptly addressed. Continued low oxygen levels may lead to respiratory or cardiac arrest. Oxygen therapy may be used to assist in raising blood oxygen levels. Oxygenation occurs when oxygen molecules () enter the tissues of the body. For example, blood is oxygenated in the lungs, where oxygen molecules travel from the air and into the blood. Oxygenation is commonly used to refer to medical oxygen saturation. Definition In medicine, oxygen saturation, commonly referred to as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baroreceptor
Baroreceptors (or archaically, pressoreceptors) are stretch receptors that sense blood pressure. Thus, increases in the pressure of blood vessel triggers increased action potential generation rates and provides information to the central nervous system. This sensory information is used primarily in autonomic reflexes that in turn influence the heart cardiac output and vascular smooth muscle to influence vascular resistance. Baroreceptors act immediately as part of a negative feedback system called the baroreflex as soon as there is a change from the usual mean arterial blood pressure, returning the pressure toward a normal level. These reflexes help regulate short-term blood pressure. The solitary nucleus in the medulla oblongata of the brain recognizes changes in the firing rate of action potentials from the baroreceptors, and influences cardiac output and systemic vascular resistance. Baroreceptors can be divided into two categories based on the type of blood vessel in whic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homeostasis
In biology, homeostasis (British English, British also homoeostasis; ) is the state of steady internal physics, physical and chemistry, chemical conditions maintained by organism, living systems. This is the condition of optimal functioning for the organism and includes many variables, such as body temperature and fluid balance, being kept within certain pre-set limits (homeostatic range). Other variables include the pH of extracellular fluid, the concentrations of sodium, potassium, and calcium ions, as well as the blood sugar level, and these need to be regulated despite changes in the environment, diet, or level of activity. Each of these variables is controlled by one or more regulators or homeostatic mechanisms, which together maintain life. Homeostasis is brought about by a natural resistance to change when already in optimal conditions, and equilibrium is maintained by many regulatory mechanisms; it is thought to be the central motivation for all organic action. All home ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arterial Stiffness
Arterial stiffness occurs as a consequence of biological aging, arteriosclerosis and genetic disorders, such as Marfan, Williams, and Ehlers-Danlos syndromes. Inflammation plays a major role in arteriosclerosis and arterial stiffness. Increased arterial stiffness is associated with an increased risk of cardiovascular events such as myocardial infarction, hypertension, heart failure, and stroke. The World Health Organization identified cardiovascular disease as the leading cause of death globally in 2019. Degenerative changes that occur with age in the walls of large elastic arteries are thought to contribute to increased stiffening over time, including the disruption of lamellar elastin structures within the wall, possibly due to repeated cycles of mechanical stress; inflammation; changes in arterial collagen proteins, partially as a compensatory mechanism against the loss of arterial elastin and partially due to fibrosis; and crosslinking of adjacent collagen fibers by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Systemic Vascular Resistance
Vascular resistance is the resistance that must be overcome for blood to flow through the circulatory system. The resistance offered by the systemic circulation is known as the systemic vascular resistance or may sometimes be called by another term total peripheral resistance, while the resistance caused by the pulmonary circulation is known as the pulmonary vascular resistance. Vasoconstriction (i.e., decrease in the diameter of arteries and arterioles) increases resistance, whereas vasodilation (increase in diameter) decreases resistance. Blood flow and cardiac output are related to blood pressure and inversely related to vascular resistance. Measurement The measurement of vascular resistance is challenging in most situations. The standard method is by the use of a Pulmonary artery catheter. This is common in ICU settings but impractical is most other settings. Units for measuring Units for measuring vascular resistance are dyn·s·cm−5, pascal seconds per cubic metre (Pa·s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiac Output
In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols Q, \dot Q, or \dot Q_ , edited by Catherine E. Williamson, Phillip Bennett is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single Ventricle (heart), ventricle of the heart, per unit time (usually measured per minute). Cardiac output (CO) is the product of the heart rate (HR), i.e. the number of heartbeats per minute (bpm), and the stroke volume (SV), which is the volume of blood pumped from the left ventricle per beat; thus giving the formula: :CO = HR \times SV Values for cardiac output are usually denoted as L/min. For a healthy individual weighing 70 kg, the cardiac output at rest averages about 5 L/min; assuming a heart rate of 70 beats/min, the stroke volume would be approximately 70 mL. Because cardiac output is related to the quantity of blood delivered to various parts of the body, it is an important com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Standard Deviation
In statistics, the standard deviation is a measure of the amount of variation of the values of a variable about its Expected value, mean. A low standard Deviation (statistics), deviation indicates that the values tend to be close to the mean (also called the expected value) of the set, while a high standard deviation indicates that the values are spread out over a wider range. The standard deviation is commonly used in the determination of what constitutes an outlier and what does not. Standard deviation may be abbreviated SD or std dev, and is most commonly represented in mathematical texts and equations by the lowercase Greek alphabet, Greek letter Sigma, σ (sigma), for the population standard deviation, or the Latin script, Latin letter ''s'', for the sample standard deviation. The standard deviation of a random variable, Sample (statistics), sample, statistical population, data set, or probability distribution is the square root of its variance. (For a finite population, v ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ambulatory Blood Pressure
Ambulatory blood pressure, as opposed to office blood pressure and home blood pressure, is the blood pressure over the course of the full 24-hour sleep-wake cycle. Ambulatory blood pressure monitoring (ABPM) measures blood pressure at regular intervals throughout the day and night. It avoids the white coat hypertension effect in which a patient's blood pressure is elevated during the examination process due to nervousness and anxiety caused by being in a clinical setting. ABPM can also detect the reverse condition, masked hypertension, where the patient has normal blood pressure during the examination but uncontrolled blood pressure outside the clinical setting, masking a high 24-hour average blood pressure. Out-of-office measurements are highly recommended as an adjunct to office measurements by almost all hypertension organizations. Blood pressure variability 24-hour, non-invasive ambulatory blood pressure (BP) monitoring allows estimates of cardiac risk factors including exces ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mercury (element)
Mercury is a chemical element; it has Symbol (chemistry), symbol Hg and atomic number 80. It is commonly known as quicksilver. A Heavy metal element, heavy, silvery d-block element, mercury is the only metallic element that is known to be liquid at standard temperature and pressure; the only other element that is liquid under these conditions is the halogen bromine, though metals such as caesium, gallium, and rubidium melt just above room temperature. Mercury occurs in deposits throughout the world mostly as cinnabar (mercuric sulfide). The red pigment vermilion is obtained by Mill (grinding), grinding natural cinnabar or synthetic mercuric sulfide. Exposure to mercury and mercury-containing organic compounds is toxic to the nervous system, immune system and kidneys of humans and other animals; mercury poisoning can result from exposure to water-soluble forms of mercury (such as mercuric chloride or methylmercury) either directly or through mechanisms of biomagnification. Mercu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aneroid Gauge
Pressure measurement is the measurement of an applied force by a fluid (liquid or gas) on a surface. Pressure is typically measured in units of force per unit of surface area. Many techniques have been developed for the measurement of pressure and vacuum. Instruments used to measure and display pressure mechanically are called pressure gauges, vacuum gauges or compound gauges (vacuum & pressure). The widely used Bourdon gauge is a mechanical device, which both measures and indicates and is probably the best known type of gauge. A vacuum gauge is used to measure pressures lower than the ambient atmospheric pressure, which is set as the zero point, in negative values (for instance, −1 bar or −760 mmHg equals total vacuum). Most gauges measure pressure relative to atmospheric pressure as the zero point, so this form of reading is simply referred to as "gauge pressure". However, anything greater than total vacuum is technically a form of pressure. For very low pressu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Artery
An artery () is a blood vessel in humans and most other animals that takes oxygenated blood away from the heart in the systemic circulation to one or more parts of the body. Exceptions that carry deoxygenated blood are the pulmonary arteries in the pulmonary circulation that carry blood to the lungs for oxygenation, and the umbilical arteries in the fetal circulation that carry deoxygenated blood to the placenta. It consists of a multi-layered artery wall wrapped into a tube-shaped channel. Arteries contrast with veins, which carry deoxygenated blood back towards the heart; or in the pulmonary and fetal circulations carry oxygenated blood to the lungs and fetus respectively. Structure The anatomy of arteries can be separated into gross anatomy, at the macroscopic scale, macroscopic level, and histology, microanatomy, which must be studied with a microscope. The arterial system of the human body is divided into systemic circulation, systemic arteries, carrying blood from the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
