Arsenophonus Arthropodicus
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Arsenophonus Arthropodicus
''Candidatus'' Arsenophonus arthropodicus is a Gram-negative and intracellular secondary (S) endosymbiont that belongs to the genus '' Arsenophonus''. This bacterium is found in the Hippoboscid louse fly, ''Pseudolynchia canariensis''. S-endosymbionts are commonly found in distinct tissues. Strains of recovered ''Arsenophonus'' found in arthropods share 99% sequence identification in the 16S rRNA gene across all species. ''Arsenophonus''-host interactions involve parasitism and mutualism, including a popular mechanism of "male-killing" found commonly in a related species, ''Arsenophonus nasoniae''. This species is considered "''Ca.'' A. arthropodicus" due it being as of yet uncultured. Isolation and genome identification Isolation Amplified 16S rRNA gene sequences of ''Phoenix canariensis'' pupal DNA showed ''Arsenophonus'' detection in hemocytes, gut, fat body, and reproductive tissues indicating distribution of bacterium throughout hosts tissues. Lab cultured bacteria found i ...
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Bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the fixation of nitrogen from the atmosphere. The nutrient cycle includes the decomposition of dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulphide and methane, to energy. Bacteria also live in symbiotic and parasitic relationsh ...
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Pseudomonadota
Pseudomonadota (synonym Proteobacteria) is a major phylum of Gram-negative bacteria. The renaming of phyla in 2021 remains controversial among microbiologists, many of whom continue to use the earlier names of long standing in the literature. The phylum Proteobacteria includes a wide variety of pathogenic genera, such as ''Escherichia'', '' Salmonella'', ''Vibrio'', ''Yersinia'', ''Legionella'', and many others.Slonczewski JL, Foster JW, Foster E. Microbiology: An Evolving Science 5th Ed. WW Norton & Company; 2020. Others are free-living (nonparasitic) and include many of the bacteria responsible for nitrogen fixation. Carl Woese established this grouping in 1987, calling it informally the "purple bacteria and their relatives". Because of the great diversity of forms found in this group, it was later informally named Proteobacteria, after Proteus, a Greek god of the sea capable of assuming many different shapes (not after the Proteobacteria genus ''Proteus''). In 2021 the Internat ...
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Gammaproteobacteria
Gammaproteobacteria is a class of bacteria in the phylum Pseudomonadota (synonym Proteobacteria). It contains about 250 genera, which makes it the most genera-rich taxon of the Prokaryotes. Several medically, ecologically, and scientifically important groups of bacteria belong to this class. It is composed by all Gram-negative microbes and is the most phylogenetically and physiologically diverse class of Proteobacteria. These microorganisms can live in several terrestrial and marine environments, in which they play various important roles, including ''extreme environments'' such as hydrothermal vents. They generally have different shapes - rods, curved rods, cocci, spirilla, and filaments and include free living bacteria, biofilm formers, commensals and symbionts, some also have the distinctive trait of being bioluminescent. Metabolisms found in the different genera are very different; there are both aerobic and anaerobic (obligate or facultative) species, chemolithoautotrophic ...
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Enterobacterales
Enterobacterales is an order of Gram-negative, non-spore forming, facultatively anaerobic, rod-shaped bacteria with the class Gammaproteobacteria. The type genus of this order is ''Enterobacter.'' The name Enterobacterales is derived from the Latin term ''Enterobacter'', referring the type genus of the order and the suffix "-ales", an ending used to denote an order. Together, Enterobacterales refers to an order whose nomenclatural type is the genus ''Enterobacter''. Historical Identification and Systematics Enterobacterales was proposed in 2005 under the name "Enterobacteriales". However, the name "Enterobacteriales" was not validated according to the rules of the ''International Code of Nomenclature of Prokaryotes,'' thus it lacked standing in nomenclature, so the name was written in parentheses. "Enterobacteriales" was a monotypic order, containing only the family '' Enterobacteriaceae'', and shared its type genus ''Escherichia''.NCBEnterobacteralesaccessed 9 Mar 2013 The ...
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Morganellaceae
The Morganellaceae are a family of Gram-negative bacteria that include some important human pathogens formerly classified as Enterobacteriaceae. This family is a member of the order Enterobacterales in the class Gammaproteobacteria of the phylum Pseudomonadota. Genera in this family include the type genus '' Morganella'', along with '' Arsenophonus, Cosenzaea, Moellerella, Photorhabdus, Proteus, Providencia'' and ''Xenorhabdus''. The name ''Morganellaceae'' is derived from the Latin term ''Morganella'', referring the type genus of the family and the suffix "-aceae", an ending used to denote a family. Together, ''Morganellaceae'' refers to a family whose nomenclatural type is the genus ''Morganella''. Human pathogens A number of Morganellaceae bacterial species are opportunistic human pathogens, including ''Proteus'', '' Providencia'', and occasionally '' Morganella'' in nosocomial settings. ''Proteus'' Three ''Proteus'' species '' P. vulgaris'', '' P. mirabilis'', and ...
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Arsenophonus
''Arsenophonus'' is a genus of Morganellaceae, of the Gammaproteobacteria. Members of the ''Arsenophonus'' genus are increasingly discovered bacterial symbionts of arthropods that are estimated to infect over 5% of arthropod species globally and form a variety of relationships with hosts across the mutualism parasitism continuum. ''Arsenophonus'' bacteria have been identified in a diversity of insect taxa, including economically important species such as the Western honey bee and the rice pest ''Nilaparvata lugens''. The majority of work on ''Arsenophonus'' has been done on the type species '' Arsenophonus nasoniae'' for which genetic manipulation has been successful in achieving ''in vivo'' tracking of the bacterium. '' Arsenophonus nasoniae'' infects ''Nasonia'' parasitic wasps, is vertically transmitted through eggs, and has a male-killing phenotype. Infection with '' Arsenophonus nasoniae'' triggers the death of approximately 80% of the wasps male offspring. Killing male of ...
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Gram-negative
Gram-negative bacteria are bacteria that do not retain the crystal violet stain used in the Gram staining method of bacterial differentiation. They are characterized by their cell envelopes, which are composed of a thin peptidoglycan cell wall sandwiched between an inner cytoplasmic cell membrane and a bacterial outer membrane. Gram-negative bacteria are found in virtually all environments on Earth that support life. The gram-negative bacteria include the model organism ''Escherichia coli'', as well as many pathogenic bacteria, such as ''Pseudomonas aeruginosa'', ''Chlamydia trachomatis'', and ''Yersinia pestis''. They are a significant medical challenge as their outer membrane protects them from many antibiotics (including penicillin), detergents that would normally damage the inner cell membrane, and lysozyme, an antimicrobial enzyme produced by animals that forms part of the innate immune system. Additionally, the outer leaflet of this membrane comprises a complex lipo ...
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Endosymbiont
An ''endosymbiont'' or ''endobiont'' is any organism that lives within the body or cells of another organism most often, though not always, in a mutualistic relationship. (The term endosymbiosis is from the Greek: ἔνδον ''endon'' "within", σύν ''syn'' "together" and βίωσις ''biosis'' "living".) Examples are nitrogen-fixing bacteria (called rhizobia), which live in the root nodules of legumes, single-cell algae inside reef-building corals and bacterial endosymbionts that provide essential nutrients to insects. There are two types of symbiont transmissions. In horizontal transmission, each new generation acquires free living symbionts from the environment. An example is the nitrogen-fixing bacteria in certain plant roots. Vertical transmission takes place when the symbiont is transferred directly from parent to offspring. It is also possible for both to be involved in a mixed-mode transmission, where symbionts are transferred vertically for some generation bef ...
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Pseudolynchia Canariensis
''Pseudolynchia canariensis'', the pigeon louse fly or pigeon fly, is a species of biting fly in the family of louse flies, Hippoboscidae. Distribution ''Pseudolynchia canariensis'' are species-specific (Columbidae) obligate ectoparasites potentially found in many parts of world where domestic pigeons are kept. Known from wild or feral hosts in continental Africa, the Mediterranean Sub-region, Afghanistan, India, Bangladesh, Nepal, Thailand, Taiwan, Ryukyu Islands, the Philippines, Malaya, and Indonesia, as well as North America and South America in warmer latitudes. Hosts In 1931, G. Robert Coatney conducted an experiment to determine if pigeon louse flies would bite humans and survive on human blood and he found they could not. The only wild hosts are pigeons and doves (Columbidae). In domestic settings they have been recorded from 33 genera, 13 families and 8 orders of birds. Disease vector ''Pseudolynchia canariensis'' is the definitive host (sexual reproduction takes place ...
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Arthropod
Arthropods (, (gen. ποδός)) are invertebrate animals with an exoskeleton, a Segmentation (biology), segmented body, and paired jointed appendages. Arthropods form the phylum Arthropoda. They are distinguished by their jointed limbs and Arthropod cuticle, cuticle made of chitin, often Mineralization (biology), mineralised with calcium carbonate. The arthropod body plan consists of segments, each with a pair of appendages. Arthropods are bilaterally symmetrical and their body possesses an exoskeleton, external skeleton. In order to keep growing, they must go through stages of moulting, a process by which they shed their exoskeleton to reveal a new one. Some species have wings. They are an extremely diverse group, with up to 10 million species. The haemocoel, an arthropod's internal cavity, through which its haemolymph – analogue of blood – circulates, accommodates its interior Organ (anatomy), organs; it has an open circulatory system. Like their exteriors, the internal or ...
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Vancomycin
Vancomycin is a glycopeptide antibiotic medication used to treat a number of bacterial infections. It is recommended intravenously as a treatment for complicated skin infections, bloodstream infections, endocarditis, bone and joint infections, and meningitis caused by methicillin-resistant ''Staphylococcus aureus''. Blood levels may be measured to determine the correct dose. Vancomycin is also taken by mouth as a treatment for severe ''Clostridium difficile'' colitis. When taken by mouth it is poorly absorbed. Common side effects include pain in the area of injection and allergic reactions. Occasionally, hearing loss, low blood pressure, or bone marrow suppression occur. Safety in pregnancy is not clear, but no evidence of harm has been found, and it is likely safe for use when breastfeeding. It is a type of glycopeptide antibiotic and works by blocking the construction of a cell wall. Vancomycin was approved for medical use in the United States in 1958. It is on the World ...
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