3',4'-Dimethoxy-α-pyrrolidinopentiophenone
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3',4'-Dimethoxy-α-pyrrolidinopentiophenone
3',4'-Dimethoxy-α-pyrrolidinopentiophenone (also known as O-2512, 3,4-dimethoxy-α-PVP, 3,4-DMPV, DMPVP) is a synthetic stimulant drug of the cathinone class that has been sold online as a designer drug. It is a relatively weak inhibitor of serotonin reuptake and has little affinity ''in vitro'' for dopamine or noradrenaline transporters. See also * 4Cl-PVP * 4F-PVP * 4-Et-PVP * Alpha-Pyrrolidinobutiophenone, α-PBP * Alpha-Pyrrolidinohexiophenone, α-PHP * Alpha-Pyrrolidinopropiophenone, α-PPP * Alpha-Pyrrolidinopentiophenone, α-PVP * Alpha-Pyrrolidinopentiothiophenone, α-PVT * MFPVP * 4'-Methoxy-α-pyrrolidinopentiophenone, MOPVP * MDPV * O-2390 * Pyrovalerone References

Alpha-Propylphenethylamines Designer drugs Methoxyphenethylamines Norepinephrine–dopamine reuptake inhibitors Propyl compounds Pyrrolidinophenones Stimulants {{nervous-system-drug-stub ...
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4-Et-PVP
4-Ethyl-alpha-Pyrrolidinovalerophenone (4-Et-PVP) is a recreational designer drug from the substituted cathinone family, with stimulant effects. It was first identified in Hungary in March 2019. See also * 3,4-EtPV * 3F-PVP * 4-EMC * 4-Ethylamphetamine * 4F-PVP * 4Cl-PVP * 4'-Methoxy-α-pyrrolidinopentiophenone, MOPVP * 3',4'-Dimethoxy-α-pyrrolidinopentiophenone, DMPVP * MDPV * Pyrovalerone * RTI-83 References

Alpha-Propylphenethylamines Pyrrolidinophenones Designer drugs Serotonin-norepinephrine-dopamine releasing agents {{nervous-system-drug-stub ...
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4'-Methoxy-α-pyrrolidinopentiophenone
4'-Methoxy-α-pyrrolidinopentiophenone (also known as O-2417, 4-MeO-α-PVP and MOPVP) is a stimulant drug of the cathinone class that has been sold online as a designer drug. Legal Status As of October 2015 4-MeO-α-PVP is a controlled substance in China. See also * 4Cl-PVP * 4F-PVP * 4-Et-PVP * alpha-Pyrrolidinopentiophenone * 4'-Methoxy-α-pyrrolidinopropiophenone * DMPVP * MDPV * Pyrovalerone (Centroton, 4-Methyl-β-keto-prolintane, Thymergix, O-2371) is a central nervous system (CNS) stimulant that acts as a norepinephrine–dopamine reuptake inhibitor (NDRI). It was developed in the 1980s and had briefly been approved in Spain an ... References Alpha-Propylphenethylamines Designer drugs Methoxyphenethylamines Norepinephrine–dopamine reuptake inhibitors Pyrrolidinophenones Propyl compounds 4-Methoxyphenyl compounds {{nervous-system-drug-stub ...
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MFPVP
MFPVP (3-Methyl-4-fluoro-α-pyrrolidinovalerophenone) is a psychoactive agent new psychoactive drugs/medications from the substituted cathinone family, with stimulant effects. It was first identified in Sweden in April 2020 and was among the most widely encountered substituted cathinone derivatives in 2021, though it since appears to have declined in prevalence. It is illegal in Virginia. See also * 3F-PVP * 4F-PVP * 4F-PHP * 4Cl-PVP * 4-Cl-3-MMC * MOPVP * DMPVP * MDPV * O-2390 * Pyrovalerone (Centroton, 4-Methyl-β-keto-prolintane, Thymergix, O-2371) is a central nervous system (CNS) stimulant that acts as a norepinephrine–dopamine reuptake inhibitor (NDRI). It was developed in the 1980s and had briefly been approved in Spain an ... References Alpha-Propylphenethylamines Pyrrolidinophenones Designer drugs {{nervous-system-drug-stub ...
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Hydrochloride
In chemistry, a hydrochloride is an acid salt resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic base (e.g. an amine). An alternative name is chlorhydrate, which comes from French. An archaic alternative name is muriate, derived from hydrochloric acid's ancient name: muriatic acid. Uses Converting amines into their hydrochlorides is a common way to improve their water solubility, which can be desirable for substances used in medications. The European Pharmacopoeia lists more than 200 hydrochlorides as active ingredients in medications. These hydrochlorides, compared to free bases, may more readily dissolve in the gastrointestinal tract and be absorbed into the bloodstream more quickly. Additionally, many hydrochlorides of amines have a longer shelf-life than their respective free bases. Amine hydrochlorides represent latent forms of a more reactive free base. In this regard, formation of an amine hydrochloride confers protection ...
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Propyl Compounds
In organic chemistry, a propyl group is a three-carbon alkyl substituent with chemical formula for the linear form. This substituent form is obtained by removing one hydrogen atom attached to the terminal carbon of propane. A propyl substituent is often represented in organic chemistry with the symbol Pr (not to be confused with the element praseodymium). An isomeric form of propyl is obtained by moving the point of attachment from a terminal carbon atom to the central carbon atom, named isopropyl or 1-methylethyl. To maintain four substituents on each carbon atom, one hydrogen atom has to be moved from the middle carbon atom to the carbon atom which served as attachment point in the ''n''-propyl variant, written as . Linear propyl is sometimes termed normal and hence written with a prefix ''n''- (i.e., ''n-''propyl), as the absence of the prefix ''n''- does not indicate which attachment point is chosen, i.e. absence of prefix does not automatically exclude the possibility of i ...
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Methoxyphenethylamines
Methoxyphenethylamine, or monomethoxyphenethylamine, may refer to: * 2-Methoxyphenethylamine (2-MPEA) * 3-Methoxyphenethylamine (3-MPEA) * 4-Methoxyphenethylamine (4-MPEA) See also * Substituted methoxyphenethylamine * Dimethoxyphenethylamine * Trimethoxyphenethylamine * Methoxyamphetamine * Dimethoxyamphetamine * Trimethoxyamphetamine {{Chemistry index Methoxyphenethylamines ...
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Designer Drugs
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. Designer drugs include psychoactive substances that have been designated by the European Union, Australia, and New Zealand, as new psychoactive substances (NPS) as well as analogs of performance-enhancing drugs such as designer steroids. Some of these designer drugs were originally synthesized by academic or industrial researchers in an effort to discover more potent derivatives with fewer side effects and shorter duration (and possibly also because it is easier to apply for patents for new molecules) and were later co-opted for recreational use. Other designer drugs were prepared for the first time in clandestine laboratories. Because the efficacy and safety of these substances have not been thoroughly evaluated in animal and human tr ...
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Pyrovalerone
(Centroton, 4-Methyl-β-keto-prolintane, Thymergix, O-2371) is a central nervous system (CNS) stimulant that acts as a norepinephrine–dopamine reuptake inhibitor (NDRI). It was developed in the 1980s and had briefly been approved in Spain and France for chronic fatigue or lethargy and as an appetite suppressant, but was withdrawn from both markets around 2001 due to safety concerns including problems with abuse and dependence. It is closely related on a structural level to a number of other cathinone stimulants, such as α-PVP, MDPV and prolintane. Side effects of pyrovalerone include decreased appetite, anxiety, fragmented sleep or insomnia, and trembling, shaking, or muscle tremors. Withdrawal symptoms following abuse upon discontinuation often results in depression. The ''R''-enantiomer In chemistry, an enantiomer (Help:IPA/English, /ɪˈnænti.əmər, ɛ-, -oʊ-/ Help:Pronunciation respelling key, ''ih-NAN-tee-ə-mər''), also known as an optical isomer, an ...
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O-2390
O-2390 (3,4-Dichloro-alpha-PVP, DCPVP) is a recreational designer drug from the substituted cathinone family, which acts as a potent inhibitor of dopamine and noradrenaline reuptake ''in vitro'', with weaker but still significant inhibition of serotonin reuptake. See also * 3F-PVP * 4F-PVP * 4Cl-PVP * 3,4-DCMP * Chlorosipentramine * Cilobamine * Dichloropane * LR-5182 * MDPV * MFPVP * Naphyrone * Sertraline Sertraline, sold under the brand name Zoloft among others, is an Antidepressant, antidepressant medication of the selective serotonin reuptake inhibitor (SSRI) class used to treat major depressive disorder, generalized anxiety disorder, socia ... * TH-PVP References Alpha-Propylphenethylamines Designer drugs Pyrrolidinophenones Serotonin-norepinephrine-dopamine releasing agents {{nervous-system-drug-stub ...
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