RefSeq (protein)



Location (UCSC) Chr 5: 150.89 – 150.9 Mb n/a PubMed search [2] n/a Wikidata
View/Edit Human

Zinc finger protein 300 is a protein that in humans is encoded by the ZNF300 gene.[3][4] The protein encoded by this gene is a C2H2-type zinc finger DNA binding protein and a likely transcription factor.

It is antisense to the human gene, C16orf71, indicating possibility of regulated alternative expression.[5]

Clinical relevance

It is associated with Crohn's disease.[6]


  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000145908 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". 
  3. ^ Gou D, Wang J, Gao L, Sun Y, Peng X, Huang J, Li W (January 2004). "Identification and functional analysis of a novel human KRAB/C2H2 zinc finger gene ZNF300". Biochim. Biophys. Acta. 1676 (2): 203–9. doi:10.1016/j.bbaexp.2003.11.011. PMID 14746915. 
  4. ^ "Entrez Gene: zinc finger protein 300". 
  5. ^ mieg@ncbi.nlm.nih.gov, Danielle Thierry-Mieg and Jean Thierry-Mieg, NCBI/NLM/NIH,. "AceView: Gene:C16orf71, a comprehensive annotation of human, mouse and worm genes with mRNAs or ESTsAceView". www.ncbi.nlm.nih.gov. Retrieved 2017-05-20. 
  6. ^ Prescott NJ, Dominy KM, Kubo M, Lewis CM, Fisher SA, Redon R, Huang N, Stranger BE, Blaszczyk K, Hudspith B, Parkes G, Hosono N, Yamazaki K, Onnie CM, Forbes A, Dermitzakis ET, Nakamura Y, Mansfield JC, Sanderson J, Hurles ME, Roberts RG, Mathew CG (May 2010). "Independent and population-specific association of risk variants at the IRGM locus with Crohn's disease". Hum. Mol. Genet. 19 (9): 1828–39. doi:10.1093/hmg/ddq041. PMC 2850616Freely accessible. PMID 20106866. 

Further reading