Diagram of deodorization tower (Causes of Yusho disease) 01

was a mass poisoning by

polychlorinated biphenyl Polychlorinated biphenyls (PCBs) are highly carcinogenic chemical compounds, formerly used in industrial and consumer products, whose production was banned in the United States by the Toxic Substances Control Act of 1976, Toxic Substances Contro ...

s (PCBs) which occurred in northern

Kyūshū is the third-largest island of Japan's five main islands and the most southerly of the four largest islands ( i.e. excluding Okinawa). In the past, it has been known as , and . The historical regional name referred to Kyushu and its surround ...

Japan Japan ( ja, 日本, or , and formally , ''Nihonkoku'') is an island country in East Asia. It is situated in the northwest Pacific Ocean, and is bordered on the west by the Sea of Japan, while extending from the Sea of Okhotsk in the n ...

, in 1968. In January 1968, rice bran oil produced by Kanemi Company in Kyushu was contaminated with PCBs and polychlorinated dibenzofurans (PCDFs) during production. For deodorization, the oil was heated using PCB as the heating medium, circulating through pipes. Due to holes in the pipes the PCB leaked into the rice bran oil. The contaminated rice bran oil was then sold to poultry farmers for use as a feed supplement and to consumers for use in cooking. In February to March 1968, farmers started reporting that their poultry were dying due to apparent difficulty in breathing; altogether 400,000 birds died. About 14,000 people who had consumed the contaminated rice oil were affected in Japan. More than 500 died. Common symptoms included dermal and

ocular Eyes are organs of the visual system. They provide living organisms with vision, the ability to receive and process visual detail, as well as enabling several photo response functions that are independent of vision. Eyes detect light and conv ...

lesion A lesion is any damage or abnormal change in the tissue of an organism, usually caused by disease or trauma. ''Lesion'' is derived from the Latin "injury". Lesions may occur in plants as well as animals. Types There is no designated classif ...

s, irregular

menstrual cycle The menstrual cycle is a series of natural changes in hormone production and the structures of the uterus and ovaries of the female reproductive system that make pregnancy possible. The ovarian cycle controls the production and release of eggs ...

s and a lowered

immune response An immune response is a reaction which occurs within an organism for the purpose of defending against foreign invaders. These invaders include a wide variety of different microorganisms including viruses, bacteria, parasites, and fungi which coul ...

.PCB Baby Studies Part 2
Other symptoms included fatigue, headache, cough, and unusual skin sores.
Additionally, in children, there were reports of poor cognitive development. Although a decade had passed, an almost identical case occurred in

Taiwan Taiwan, officially the Republic of China (ROC), is a country in East Asia, at the junction of the East and South China Seas in the northwestern Pacific Ocean, with the People's Republic of China (PRC) to the northwest, Japan to the no ...

in 1979. Again, rice oil had been heated by pipes that leaked. On this occasion, the condition there was known as Yu-cheng disease (). Similar symptoms and effects of the PCBs and PCDFs were shown, especially in children. There have been studies undertaken on animals to understand the mechanisms of PCBs and PCDFs and their effects. Scientists discovered that low levels of PCBs could kill fish and other wildlife and as such their use in manufacturing was reduced. In 2008, a dioxin poisoning event caused the

2008 Irish pork crisis The Irish pork crisis of 2008 was a dioxin contamination incident in Ireland that led to an international recall of pork products from Ireland produced between September and early December of that year. It was disclosed in early December 2008 t ...

in which Irish pork was recalled worldwide.

See also

References

Further reading