Vector NTI
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Vector NTI was a
commercial Commercial may refer to: * a dose of advertising conveyed through media (such as - for example - radio or television) ** Radio advertisement ** Television advertisement * (adjective for:) commerce, a system of voluntary exchange of products and s ...
bioinformatics software package used by many life scientists in the early 2000s to work, among other things, with
nucleic acids Nucleic acids are biopolymers, macromolecules, essential to all known forms of life. They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous base. The two main cl ...
and proteins '' in silico''. It allowed researchers to, for example, plan a
DNA cloning Molecular cloning is a set of experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. The use of the word ''cloning'' refers to the fact that the metho ...
experiment on the computer before actually performing it in the lab. It was originally created by InforMax Inc, North Bethesda, MD in 1993 and versions in the early 2000s were well reviewed at the time. However, in 2008 it was locked and turned into a commercial software after 2008 which created problems for locked in users who were forced to buy the software to continue accessing their data on newer computers. What was previously a single software package was subsequently split into Vector NTI Express, Advanced, and Express Designer. Vector NTI was discontinued by its corporate parent Thermo Fisher at the end of 2019 and support ceased a year later.


Features

* create, annotate, analyse, and share DNA/
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, res ...
sequences * perform and save
BLAST Blast or The Blast may refer to: *Explosion, a rapid increase in volume and release of energy in an extreme manner *Detonation, an exothermic front accelerating through a medium that eventually drives a shock front Film * ''Blast'' (1997 film), ...
searches * design primers for PCR,
cloning Cloning is the process of producing individual organisms with identical or virtually identical DNA, either by natural or artificial means. In nature, some organisms produce clones through asexual reproduction. In the field of biotechnology, c ...
, sequencing or hybridisation experiments * plan cloning and run
gels A gel is a semi-solid that can have properties ranging from soft and weak to hard and tough. Gels are defined as a substantially dilute cross-linked system, which exhibits no flow when in the steady-state, although the liquid phase may still dif ...
'' in silico'' * align multiple protein or DNA sequences * search NCBI's
Entrez The Entrez (pronounced ''ɒnˈtreɪ'') Global Query Cross-Database Search System is a federated search engine, or web portal that allows users to search many discrete health sciences databases at the National Center for Biotechnology Information ...
, view, and save DNAs, proteins, and citations * edit chromatogram data, assemble into contigs


See also

* Bioinformatics * Cloning vector * Computational biology *
Expression vector An expression vector, otherwise known as an expression construct, is usually a plasmid or virus designed for gene expression in cells. The vector is used to introduce a specific gene into a target cell, and can commandeer the cell's mechanism for ...
*
List of open source bioinformatics software This is a list of computer software which is made for bioinformatics and released under open-source software licenses with articles in Wikipedia. See also * List of sequence alignment software * List of open-source healthcare software * List o ...
* Restriction map *
Vector (molecular biology) In molecular cloning, a vector is any particle (e.g., plasmids, cosmids, Lambda phages) used as a vehicle to artificially carry a foreign nucleic sequence – usually DNA – into another cell, where it can be replicated and/or expressed. A ...
*
Vector DNA In molecular cloning, a vector is any particle (e.g., plasmids, cosmids, Lambda phages) used as a vehicle to artificially carry a foreign nucleic sequence – usually DNA – into another cell, where it can be replicated and/or expressed. A ve ...


References

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External links

Description of software
Vector NTI homepage at Invitrogen.com

Vector NTI at openwetware.org


Tutorials
Vector NTI tutorial at NorthWestern.edu




Other
description of Vector NTI Viewer
Bioinformatics software