Uveoparotitis
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Uveoparotitis is a symptom of
sarcoidosis Sarcoidosis (also known as ''Besnier-Boeck-Schaumann disease'') is a disease involving abnormal collections of inflammatory cells that form lumps known as granulomata. The disease usually begins in the lungs, skin, or lymph nodes. Less commonly a ...
. It describes a
chronic inflammation Chronic systemic inflammation (SI) is the result of release of pro-inflammatory cytokines from immune-related cells and the chronic activation of the innate immune system. It can contribute to the development or progression of certain conditions ...
of the
parotid gland The parotid gland is a major salivary gland in many animals. In humans, the two parotid glands are present on either side of the mouth and in front of both ears. They are the largest of the salivary glands. Each parotid is wrapped around the ma ...
(
parotitis Parotitis is an inflammation of one or both parotid glands, the major salivary glands located on either side of the face, in humans. The parotid gland is the salivary gland most commonly affected by inflammation. Etymology From Greek παρωτῖ ...
) and part of the eye called the
uvea The uvea (; Lat. ''uva'', "grape"), also called the ''uveal layer'', ''uveal coat'', ''uveal tract'', ''vascular tunic'' or ''vascular layer'' is the pigmented middle of the three concentric layers that make up an eye. History and etymolog ...
(
uveitis Uveitis () is inflammation of the uvea, the pigmented layer of the eye between the inner retina and the outer fibrous layer composed of the sclera and cornea. The uvea consists of the middle layer of pigmented vascular structures of the eye and in ...
). There is also a phenomenon called Waldenström's uveoparotitis, where the symptom is related to
Heerfordt's syndrome Heerfordt syndrome is a rare manifestation of sarcoidosis. The symptoms include inflammation of the eye (uveitis), swelling of the parotid gland, chronic fever, and in some cases, :wikt:palsy, palsy of the facial nerves. Causes The exact cause ...
. The condition was first described in 1909.


Signs and symptoms

Uveoparotitis is characterized by parotitis, uveitis and low grade fever. Parotitis leads to swelling and enlargement of the parotid glands, while uveitis causes eye redness, pain and blurred vision. Weakness of the facial muscles (cranial nerve palsy) may occur, which particularly affect the seventh cranial nerve.


References


Further reading

* * Eye diseases {{Symptom-stub