Umeclidinium bromide (trade name Incruse Ellipta) is a long-acting

muscarinic antagonist A muscarinic receptor antagonist (MRA) is a type of anticholinergic agent that blocks the activity of the muscarinic acetylcholine receptor. The muscarinic receptor is a protein involved in the transmission of signals through certain parts of the ...

approved for the maintenance treatment of

chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by long-term respiratory symptoms and airflow limitation. The main symptoms include shortness of breath and a cough, which may or may not produce ...

(COPD). It is also approved for this indication in combination with

vilanterol Vilanterol ( INN, USAN) is an ultra-long-acting β2 adrenoreceptor agonist (ultra-LABA), which was approved in May 2013 in combination with fluticasone furoate for sale as Breo Ellipta by GlaxoSmithKline for the treatment of chronic obstructive ...

(as

umeclidinium bromide/vilanterol Umeclidinium bromide/vilanterol, sold under the brand name Anoro Ellipta, among others, is a fixed-dose combination medication for the treatment of chronic obstructive pulmonary disease Chronic obstructive pulmonary disease (COPD) is a type o ...

) and also as a triple-therapy combination as

fluticasone furoate/umeclidinium bromide/vilanterol Fluticasone furoate/umeclidinium bromide/vilanterol, sold under the brand name Trelegy Ellipta among others, is a fixed-dose combination inhaled medication that is used for the maintenance treatment of chronic obstructive pulmonary disease (COPD ...

. It is on the

World Health Organization's List of Essential Medicines The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health s ...

. In 2020, it was the 245th most commonly prescribed medication in the United States, with more than 1million prescriptions.

References

External links

* * Bromides Drugs acting on the respiratory system GSK plc brands Muscarinic antagonists Quaternary ammonium compounds Quinuclidines Bronchodilators {{respiratory-system-drug-stub