USS ''Colorado'' may refer to:
* , a three-masted steam screw frigate in commission from 1858–1876
* , a ''Pennsylvania''-class armored cruiser in commission from 1905–1927
* , a ''Colorado''-class battleship in commission from 1923–1947
* , a ''Virginia''-class nuclear-powered fast attack submarine commissioned in 2018, in active service
In fiction:
* USS ''Colorado'' (SSBN-753), a fictional ''Ohio''-class submarine featured in the 2012 TV series
''Last Resort''
{{DEFAULTSORT:Colorado, Uss
United States Navy ship names