UBP-302
   HOME

TheInfoList



OR:

UBP-302 is a highly selective kainate receptor
antagonist An antagonist is a character in a story who is presented as the chief foe of the protagonist. Etymology The English word antagonist comes from the Greek ἀνταγωνιστής – ''antagonistēs'', "opponent, competitor, villain, enemy, riv ...
used in the study of many
neurological Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal ...
processes. It is active at
micromolar Molar concentration (also called molarity, amount concentration or substance concentration) is a measure of the concentration of a chemical species, in particular of a solute in a solution, in terms of amount of substance per unit volume of sol ...
concentration within an ''
in vitro ''In vitro'' (meaning in glass, or ''in the glass'') studies are performed with microorganisms, cells, or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in biology an ...
'' preparation and specifically targets the GluK1 ( iGluR5) subunit of the receptor. This compound was developed at the
University of Bristol , mottoeng = earningpromotes one's innate power (from Horace, ''Ode 4.4'') , established = 1595 – Merchant Venturers School1876 – University College, Bristol1909 – received royal charter , type ...
. UBP-310 and UBP-316 (ACET) are related N3-substituted willardiine derivatives.


References

Benzoic acids Pyrimidines Amino acids Kainate receptor antagonists {{nervous-system-drug-stub