U46619 is a stable synthetic
analog
Analog or analogue may refer to:
Computing and electronics
* Analog signal, in which information is encoded in a continuous variable
** Analog device, an apparatus that operates on analog signals
*** Analog electronics, circuits which use analo ...
of the endoperoxide
prostaglandin
The prostaglandins (PG) are a group of physiologically active lipid compounds called eicosanoids having diverse hormone-like effects in animals. Prostaglandins have been found in almost every tissue in humans and other animals. They are derive ...
PGH
2 first prepared in 1975, and acts as a thromboxane A
2 (TP) receptor agonist. It potently stimulates TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various in vitro preparations and exhibits many properties similar to thromboxane A
2, including shape change and aggregation of platelets and smooth muscle contraction. U46619 is a
vasoconstrictor that mimics the hydroosmotic effect of
vasopressin.
References
Prostaglandins
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