The Translational Genomics Research Institute (TGen) is a

non-profit A nonprofit organization (NPO) or non-profit organisation, also known as a non-business entity, not-for-profit organization, or nonprofit institution, is a legal entity organized and operated for a collective, public or social benefit, in co ...

genomics Genomics is an interdisciplinary field of biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dim ...

research institute A research institute, research centre, research center or research organization, is an establishment founded for doing research. Research institutes may specialize in basic research or may be oriented to applied research. Although the term often i ...

based in Arizona, United States.

History and activities

TGen was established in 2002 by

Jeffrey Trent Jeffrey M. Trent is the founding president and director of the Translational Genomics Research Institute. He has been Vice President and Research Director of the Van Andel Institute since 2009. He was the founding director of NIH's National Human ...

Phoenix, Arizona Phoenix ( ; nv, Hoozdo; es, Fénix or , yuf-x-wal, Banyà:nyuwá) is the List of capitals in the United States, capital and List of cities and towns in Arizona#List of cities and towns, most populous city of the U.S. state of Arizona, with 1 ...

, United States. The Institute began with a investment from Arizona public- and private-sector investors. TGen conducts research on a number of human disorders including

Alzheimer's disease Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in remembering recent events. As ...

autism The autism spectrum, often referred to as just autism or in the context of a professional diagnosis autism spectrum disorder (ASD) or autism spectrum condition (ASC), is a neurodevelopmental condition (or conditions) characterized by difficulti ...

Parkinson's Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...

diabetes Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ...

, and numerous forms of

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...

and a variety of other complex human diseases. This internationally recognized institute has helped to generate a strong foundation for Arizona's growing role in scientific research and cutting edge

biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used ...

. The emerging field of translational genomics research harnesses the power of new discoveries resulting from the

Human Genome Project The Human Genome Project (HGP) was an international scientific research project with the goal of determining the base pairs that make up human DNA, and of identifying, mapping and sequencing all of the genes of the human genome from both ...

and applying them to the development of improved diagnostics,

prognostics Prognostics is an engineering discipline focused on predicting the time at which a system or a component will no longer perform its intended function. This lack of performance is most often a failure beyond which the system can no longer be used to ...

, and therapies for cancer,

neurological Neurology (from el, νεῦρον (neûron), "string, nerve" and the suffix -logia, "study of") is the branch of medicine dealing with the diagnosis and treatment of all categories of conditions and disease involving the brain, the spinal c ...

disorders, diabetes and other complex

disease A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...

TGen Administration

* Jeffrey M. Trent, Ph.D.,

President President most commonly refers to: *President (corporate title) * President (education), a leader of a college or university * President (government title) President may also refer to: Automobiles * Nissan President, a 1966–2010 Japanese ...

& Scientific Director * Sunil Sharma, MD FACP, Deputy Director * Michael Bassoff, President, TGen Foundation *

Daniel Von Hoff Daniel D. Von Hoff is the physician in chief and director of translational research at Translational Genomics Research Institute (TGen), and current Virginia G. Piper Distinguished Chair for Innovative Cancer Research at HonorHealth Clinical Resea ...

, M.D., F.A.C.P., Executive Vice President, Physician-in-Chief * Tess Burleson, MBA, CPA, Chief Operating Officer and President, TGen Accelerators * Chuck Coleson, Chief Financial Officer * Galen Perry, Vice President, Marketing and Communications * Brady Young, Vice President, Human Resources * Kendall Van Keuren-Jensen, co-Director

References

External links

* {{authority control Genetics or genomics research institutions Bioinformatics organizations Research institutes in Arizona Research institutes established in 2002 Organizations based in Arizona 2002 establishments in Arizona