A tranquilizer is a drug that is designed for the treatment of anxiety, fear, tension, agitation, and disturbances of

the mind The mind is the set of faculties responsible for all mental phenomena. Often the term is also identified with the phenomena themselves. These faculties include thought, imagination, memory, will, and sensation. They are responsible for vari ...

, specifically to reduce states of

anxiety Anxiety is an emotion which is characterized by an unpleasant state of inner turmoil and includes feelings of dread over anticipated events. Anxiety is different than fear in that the former is defined as the anticipation of a future threat wh ...

and tension.

Etymology

Tranquilizer, as a term, was first used by F.F. Yonkman (1953), from the conclusions of investigative studies using the drug

reserpine Reserpine is a drug that is used for the treatment of high blood pressure, usually in combination with a thiazide diuretic or vasodilator. Large clinical trials have shown that combined treatment with reserpine plus a thiazide diuretic reduces ...

, which showed the drug had a calming effect on all animals to which it was administered. Reserpine is a centrally acting

Rauwolfia ''Rauvolfia'' (sometimes spelled ''Rauwolfia'') is a genus of evergreen trees and shrubs, commonly known as devil peppers, in the family Apocynaceae. The genus is named to honor Leonhard Rauwolf. The genus can mainly be found in tropical r ...

alkaloid Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of simila ...

. The word directly refers to the state of tranquillity in a person and other animals. The term is considered ''popular'' or ''common'', meaning it is not generally in use in the field of medicine. Specifically, it is used in reference to

antipsychotic Antipsychotics, also known as neuroleptics, are a class of psychotropic medication primarily used to manage psychosis (including delusions, hallucinations, paranoia or disordered thought), principally in schizophrenia but also in a range of ...

or neuroleptic medications. The term is generally used as a synonym for

sedative A sedative or tranquilliser is a substance that induces sedation by reducing irritability or excitement. They are CNS depressants and interact with brain activity causing its deceleration. Various kinds of sedatives can be distinguished, but ...

. When used by health care professionals, it is usually qualified or replaced with more precise terms: * minor tranquilizer usually refers to

anxiolytic An anxiolytic (; also antipanic or antianxiety agent) is a medication or other intervention that reduces anxiety. This effect is in contrast to anxiogenic agents which increase anxiety. Anxiolytic medications are used for the treatment of anxiet ...

s. * major tranquilizer might refer to

Mood stabilizer A mood stabilizer is a psychiatric medication used to treat mood disorders characterized by intense and sustained mood shifts, such as bipolar disorder and the bipolar type of schizoaffective disorder. Uses Mood stabilizers are best known for ...

s might also be considered to belong to the classification of tranquilizing agents.

Use on non-human animals

Tranquilizers are administered to animals via dart gun. If the animal only needs to be safely approached, the dart will contain a minor tranquilizer. Minor tranquilizers relieve tension and anxiety without affecting consciousness. If the animal needs to be completely still and unable to feel pain, a major tranquilizer will be used.

Police use

Tranquilizer darts are not generally included in police

less-than-lethal Non-lethal weapons, also called nonlethal weapons, less-lethal weapons, less-than-lethal weapons, non-deadly weapons, compliance weapons, or pain-inducing weapons are weapons intended to be less likely to kill a living target than conventional ...

arsenals because a human can easily be wrestled to the ground, the pain induced by the dart may cause a suspect to pull out a weapon or panic and run until they are far away resulting in the officer having to track down the unconscious suspect, a human can have a deadly allergic reaction to a tranquilizer, and because effective use requires an estimate of the target's weight —- too little tranquilizer will have no effect, and too much tranquilizer will result in death, which can lead to being convicted of second-degree unintentional murder if the target is a human. "If you shot somebody that was small, it could kill them. If you shot somebody who was big or had drugs in their system, it might not do anything." says Newett, of the Justice Department.

References

{{Reflist Drug classes defined by psychological effects

Etymology

Use on non-human animals

Police use

See also

References