Timepidium bromide (

INN Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they also provided accommo ...

) is an anticholinergic. It is used in the symptomatic treatment of visceral spasms. It is also used to relieve pain associated with various gastrointestinal disorders. The quaternary nitrogen prevents it from crossing the

blood brain barrier Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the Cell (biology), cells, and transports Metabolic waste, metabolic waste products away from th ...

, so it is peripherally acting with no central side effects. The same compound ''sans'' the quaternary methyl group and the methoxy ether is called

tipepidine Tipepidine (INN) (brand names Asverin, Antupex, Asvelik, Asvex, Bitiodin, Cofdenin A, Hustel, Nodal, Sotal), also known as tipepidine hibenzate (JAN), is a synthetic, non-opioid antitussive and expectorant of the thiambutene class. It acts as an ...

References

Muscarinic antagonists Thiophenes Quaternary ammonium compounds Piperidines Ethers Alkene derivatives Bromides Peripherally selective drugs {{gastrointestinal-drug-stub