Tetrindole was a drug candidate that functions by
reversibly inhibiting monoamine oxidase A
Monoamine oxidase A, also known as MAO-A, is an enzyme that in humans is encoded by the ''MAOA'' gene. This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, ...
; it was first synthesized in Moscow in the early 1990s. Tetrindole is similar in its chemical structure to
pirlindole (Pyrazidol), and
metralindole.
References
Carbazoles
Reversible inhibitors of MAO-A
Abandoned drugs
Monoamine oxidase inhibitors
Russian drugs
Cyclohexyl compounds
Substances discovered in the 1990s
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